DE69528644D1 - Verfahren zu Feststellung von DNA-Mulationen in einer Probe eines Patienten - Google Patents

Verfahren zu Feststellung von DNA-Mulationen in einer Probe eines Patienten

Info

Publication number
DE69528644D1
DE69528644D1 DE69528644T DE69528644T DE69528644D1 DE 69528644 D1 DE69528644 D1 DE 69528644D1 DE 69528644 T DE69528644 T DE 69528644T DE 69528644 T DE69528644 T DE 69528644T DE 69528644 D1 DE69528644 D1 DE 69528644D1
Authority
DE
Germany
Prior art keywords
mulations
patient
sample
procedure
detecting dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69528644T
Other languages
English (en)
Other versions
DE69528644T2 (de
Inventor
M Dunn
K Stevens
Denis Capatos
David E Matthews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Healthcare LLC
Original Assignee
Visible Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Visible Genetics Inc filed Critical Visible Genetics Inc
Publication of DE69528644D1 publication Critical patent/DE69528644D1/de
Application granted granted Critical
Publication of DE69528644T2 publication Critical patent/DE69528644T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69528644T 1994-07-08 1995-07-07 Verfahren zu Feststellung von DNA-Mulationen in einer Probe eines Patienten Expired - Fee Related DE69528644T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/271,946 US5545527A (en) 1994-07-08 1994-07-08 Method for testing for mutations in DNA from a patient sample
PCT/US1995/008606 WO1996007761A2 (en) 1994-07-08 1995-07-07 Method for testing for mutations in dna from a patient sample

Publications (2)

Publication Number Publication Date
DE69528644D1 true DE69528644D1 (de) 2002-11-28
DE69528644T2 DE69528644T2 (de) 2003-04-03

Family

ID=23037764

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69528644T Expired - Fee Related DE69528644T2 (de) 1994-07-08 1995-07-07 Verfahren zu Feststellung von DNA-Mulationen in einer Probe eines Patienten

Country Status (7)

Country Link
US (3) US5545527A (de)
EP (1) EP0760011B1 (de)
JP (1) JPH10504897A (de)
AU (1) AU690795B2 (de)
CA (1) CA2191233A1 (de)
DE (1) DE69528644T2 (de)
WO (1) WO1996007761A2 (de)

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US20090269814A1 (en) * 1998-05-22 2009-10-29 Murphy Patricia D Method of Analyzing a BRCA2 Gene in a Human Subject
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US6355422B1 (en) * 1998-06-24 2002-03-12 City Of Hope Single tube PCR assay for detection of chromosomal mutations: application to the inversion hotspot in the factor VIII gene including optional use of subcycling PCR
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EP1001037A3 (de) * 1998-09-28 2003-10-01 Whitehead Institute For Biomedical Research Vorselektion und Isolierung eines Einzelnukleotidpolymorphismus
US6197510B1 (en) 1998-10-01 2001-03-06 Bio-Id Diagnostic Inc. Multi-loci genomic analysis
JP3855492B2 (ja) * 1998-10-08 2006-12-13 株式会社日立製作所 混合核酸断片分析法
US6503718B2 (en) 1999-01-10 2003-01-07 Exact Sciences Corporation Methods for detecting mutations using primer extension for detecting disease
US6280947B1 (en) 1999-08-11 2001-08-28 Exact Sciences Corporation Methods for detecting nucleotide insertion or deletion using primer extension
US6235479B1 (en) 1999-04-13 2001-05-22 Bio Merieux, Inc. Methods and devices for performing analysis of a nucleic acid sample
US7209835B1 (en) * 1999-04-30 2007-04-24 Centralized Laboratory Services, Inc. Algorithmic testing in laboratory medicine
EP1130112A1 (de) 2000-02-24 2001-09-05 Epidauros Biotechnologie AG Verfahren zur Detektion wenigstens eines Allels einer Deletionsmutante
US7054758B2 (en) * 2001-01-30 2006-05-30 Sciona Limited Computer-assisted means for assessing lifestyle risk factors
WO2003065042A1 (en) * 2001-02-16 2003-08-07 Immunivest Corporation Methods and reagents for the rapid and efficient isolation of circulating cancer cells
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US7776524B2 (en) 2002-02-15 2010-08-17 Genzyme Corporation Methods for analysis of molecular events
CA2407903A1 (en) * 2002-07-29 2004-01-29 Kirk Vandezande Systems for determining optimal test order for disease diagnosis
EP1681983A4 (de) * 2003-10-14 2008-12-10 Monogram Biosciences Inc Rezeptor-tyrosin-kinase-signalpfad-analyse für diagnose und therapie
US8338578B1 (en) * 2004-03-05 2012-12-25 Quest Diagnostics Investments Incorporated Cystic fibrosis gene mutations
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US7981607B2 (en) 2004-08-27 2011-07-19 Esoterix Genetic Laboratories LLC Method for detecting recombinant event
US9109256B2 (en) 2004-10-27 2015-08-18 Esoterix Genetic Laboratories, Llc Method for monitoring disease progression or recurrence
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US8785130B2 (en) * 2005-07-07 2014-07-22 Bio-Id Diagnostic Inc. Use of markers including nucleotide sequence based codes to monitor methods of detection and identification of genetic material
US9150906B2 (en) 2006-06-28 2015-10-06 Bio-Id Diagnostic Inc. Determination of variants produced upon replication or transcription of nucleic acid sequences
JP2010506595A (ja) * 2006-10-17 2010-03-04 ライフ テクノロジーズ コーポレーション 対立遺伝子タイピングの方法
US7725466B2 (en) * 2006-10-24 2010-05-25 Tarique Mustafa High accuracy document information-element vector encoding server
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US8349557B2 (en) * 2008-06-06 2013-01-08 The Hospital For Sick Children Compositions and methods for diagnosis of autophagic vacuolar myopathy
US20150127378A1 (en) * 2012-02-11 2015-05-07 Yougene Corp. Systems for storing, processing and utilizing proprietary genetic information
JP2016538882A (ja) 2013-10-30 2016-12-15 グリーン ライフ バイオテック，エルエルシー カンキツグリーニング病のための病因定量システム及び治療方法
WO2017145739A1 (ja) * 2016-02-24 2017-08-31 富士フイルム株式会社 染色体数定量方法
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US20210032698A1 (en) * 2019-07-30 2021-02-04 The Cleveland Clinic Foundation Hsd3b1 gene and 3beta-hsd1 protein variant detection for determining corticosteroid responsiveness

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Also Published As

Publication number Publication date
WO1996007761A2 (en) 1996-03-14
DE69528644T2 (de) 2003-04-03
CA2191233A1 (en) 1996-03-14
AU4321696A (en) 1996-03-27
EP0760011A1 (de) 1997-03-05
US5545527A (en) 1996-08-13
US6270963B1 (en) 2001-08-07
WO1996007761A3 (en) 1996-03-28
EP0760011B1 (de) 2002-10-23
US5552283A (en) 1996-09-03
AU690795B2 (en) 1998-04-30
JPH10504897A (ja) 1998-05-12

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: BAYER HEALTHCARE LLC (N.D.GES.D. STAATES DELAWARE)

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee