DE69526581D1 - Synthese von conduritolepoxiden und aziridinen und verfahren zur synthese höherer disaccharide und deren verwendung - Google Patents

Synthese von conduritolepoxiden und aziridinen und verfahren zur synthese höherer disaccharide und deren verwendung

Info

Publication number
DE69526581D1
DE69526581D1 DE69526581T DE69526581T DE69526581D1 DE 69526581 D1 DE69526581 D1 DE 69526581D1 DE 69526581 T DE69526581 T DE 69526581T DE 69526581 T DE69526581 T DE 69526581T DE 69526581 D1 DE69526581 D1 DE 69526581D1
Authority
DE
Germany
Prior art keywords
synthesis
aziridines
conduritolepoxides
disaccharides
cyclitol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69526581T
Other languages
English (en)
Other versions
DE69526581T2 (de
Inventor
Tomas Hudlicky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Virginia Tech Intellectual Properties Inc
Original Assignee
Virginia Tech Intellectual Properties Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virginia Tech Intellectual Properties Inc filed Critical Virginia Tech Intellectual Properties Inc
Publication of DE69526581D1 publication Critical patent/DE69526581D1/de
Application granted granted Critical
Publication of DE69526581T2 publication Critical patent/DE69526581T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D203/26—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69526581T 1994-06-17 1995-06-14 Synthese von conduritolepoxiden und aziridinen und verfahren zur synthese höherer disaccharide und deren verwendung Expired - Lifetime DE69526581T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26158694A 1994-06-17 1994-06-17
PCT/US1995/007601 WO1995035303A1 (en) 1994-06-17 1995-06-14 Synthesis of conduritol epoxides and aziridines and methods of using such to synthesize higher disaccharides

Publications (2)

Publication Number Publication Date
DE69526581D1 true DE69526581D1 (de) 2002-06-06
DE69526581T2 DE69526581T2 (de) 2002-12-19

Family

ID=22993964

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69526581T Expired - Lifetime DE69526581T2 (de) 1994-06-17 1995-06-14 Synthese von conduritolepoxiden und aziridinen und verfahren zur synthese höherer disaccharide und deren verwendung

Country Status (6)

Country Link
EP (1) EP0765336B1 (de)
JP (1) JP4064451B2 (de)
AT (1) ATE217004T1 (de)
CA (1) CA2193097C (de)
DE (1) DE69526581T2 (de)
WO (1) WO1995035303A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5627280A (en) * 1995-02-16 1997-05-06 Virginia Tech Intellectual Properties, Inc. Synthesis of (+)-pancratistatin
US5777137A (en) * 1995-11-01 1998-07-07 University Of Florida Pancratistatins and processes for their production

Also Published As

Publication number Publication date
EP0765336A1 (de) 1997-04-02
EP0765336B1 (de) 2002-05-02
CA2193097A1 (en) 1995-12-28
CA2193097C (en) 2007-12-04
ATE217004T1 (de) 2002-05-15
WO1995035303A1 (en) 1995-12-28
JPH10502059A (ja) 1998-02-24
JP4064451B2 (ja) 2008-03-19
DE69526581T2 (de) 2002-12-19

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