DE69524981T2 - Pharmazeutische Zubereitungen enthaltend Raloxifen, einen oberflächenaktiven Stoff und ein wasserlösliches Verdünnungsmittel - Google Patents
Pharmazeutische Zubereitungen enthaltend Raloxifen, einen oberflächenaktiven Stoff und ein wasserlösliches VerdünnungsmittelInfo
- Publication number
- DE69524981T2 DE69524981T2 DE69524981T DE69524981T DE69524981T2 DE 69524981 T2 DE69524981 T2 DE 69524981T2 DE 69524981 T DE69524981 T DE 69524981T DE 69524981 T DE69524981 T DE 69524981T DE 69524981 T2 DE69524981 T2 DE 69524981T2
- Authority
- DE
- Germany
- Prior art keywords
- surfactant
- water
- pharmaceutical preparations
- preparations containing
- soluble diluent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US20491594A | 1994-03-02 | 1994-03-02 | |
SG1997000220A SG65636A1 (en) | 1994-03-02 | 1997-01-30 | Orally administrable pharmaceutical formulations |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69524981D1 DE69524981D1 (de) | 2002-02-21 |
DE69524981T2 true DE69524981T2 (de) | 2002-08-29 |
Family
ID=26665140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69524981T Expired - Lifetime DE69524981T2 (de) | 1994-03-02 | 1995-02-28 | Pharmazeutische Zubereitungen enthaltend Raloxifen, einen oberflächenaktiven Stoff und ein wasserlösliches Verdünnungsmittel |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0670162B1 (de) |
JP (1) | JP3574210B2 (de) |
CN (1) | CN1098684C (de) |
AT (1) | ATE211910T1 (de) |
AU (1) | AU684882B2 (de) |
BR (1) | BR9500758A (de) |
CA (1) | CA2143263C (de) |
CZ (1) | CZ286119B6 (de) |
DE (1) | DE69524981T2 (de) |
DK (1) | DK0670162T3 (de) |
ES (1) | ES2166799T3 (de) |
FI (1) | FI117042B (de) |
HU (1) | HU225418B1 (de) |
IL (1) | IL112746A (de) |
NO (1) | NO314286B1 (de) |
NZ (1) | NZ270588A (de) |
PL (1) | PL178858B1 (de) |
PT (1) | PT670162E (de) |
RU (1) | RU2118540C1 (de) |
SG (1) | SG65636A1 (de) |
SI (1) | SI0670162T1 (de) |
ZA (1) | ZA951497B (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
CA2223595C (en) | 1995-06-07 | 2008-08-05 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies with tamoxifen analogues |
EP0910369B1 (de) * | 1996-03-26 | 2010-04-21 | Eli Lilly And Company | Benzothiophene und denen enthaltende zusammensetzungen |
US6458811B1 (en) | 1996-03-26 | 2002-10-01 | Eli Lilly And Company | Benzothiophenes formulations containing same and methods |
YU42397A (sh) * | 1996-10-30 | 2000-10-30 | Eli Lilly And Company | Korišćenje raloksifena za pripremu leka |
ZA979720B (en) | 1996-10-30 | 1999-04-29 | Lilly Co Eli | Prophylaxis of breast cancer |
AU6959898A (en) | 1997-04-11 | 1998-11-11 | David J. Grainger | Compounds and therapies for the prevention of vascular and non-vascular pathol ogies |
US6413533B1 (en) * | 1998-05-07 | 2002-07-02 | The University Of Tennessee Research Corporation | Method for chemoprevention of prostate cancer |
JP4798924B2 (ja) * | 1999-12-13 | 2011-10-19 | 中外製薬株式会社 | ヒドロキシカルボニル−ハロゲノアルキル側鎖を有する化合物 |
KR100576149B1 (ko) | 1999-12-13 | 2006-05-03 | 추가이 세이야쿠 가부시키가이샤 | 하이드록시카보닐-할로게노알킬 측쇄를 갖는 화합물 |
AR029538A1 (es) * | 2000-07-06 | 2003-07-02 | Wyeth Corp | Composiciones farmaceuticas de agentes estrogenicos |
CZ20033119A3 (cs) * | 2001-04-24 | 2005-01-12 | Merck Patent Gmbh | Kombinovaná terapie za použití antiangiogenových činidel a TNF alfa |
CA2499819A1 (en) | 2002-09-30 | 2004-04-08 | A/S Gea Farmaceutisk Fabrik | Novel raloxifene acid addition salts and/or solvates thereof, improved method for purification of said raloxifene acid addition salts and/or solvates thereof and pharmaceutical compositions comprising these |
US20050008704A1 (en) * | 2003-07-11 | 2005-01-13 | Ray Anup Kumar | Pharmaceutical composition for solubility enhancement of hydrophobic drugs |
CA2653384C (en) | 2006-06-30 | 2017-03-14 | Iceutica Pty Ltd | Methods for the preparation of biologically active compounds in nanoparticulate form |
US20110065751A1 (en) * | 2007-10-16 | 2011-03-17 | Pharmathen S.A. | Improved pharmaceutical composition containing a selective estrogen receptor modulator and method for the preparation thereof |
CL2008003799A1 (es) * | 2007-12-21 | 2009-12-18 | Synthon Bv | Composicion farmaceutica que comprende raloxifeno en forma de tableta de liberacion inmediata; util para el tratamiento y/o prevencion de la osteoporosis. |
AU2010239081C1 (en) | 2009-04-24 | 2014-11-06 | Iceutica Pty Ltd | A novel formulation of indomethacin |
WO2011000581A2 (en) | 2009-07-02 | 2011-01-06 | Synthon B.V. | Raloxifene composition |
WO2011099942A1 (en) | 2010-02-09 | 2011-08-18 | Silverstone Pharma | New addition salts of raloxifene, process for the preparation thereof and use thereof in therapy |
CN103006570B (zh) * | 2012-10-08 | 2013-12-25 | 孙维会 | 一种阿佐昔芬速释微丸及其制备方法 |
ES2864096T3 (es) | 2012-11-30 | 2021-10-13 | Pharmathen Sa | Método nuevo para mejorar la biodisponibilidad de fármacos de baja solubilidad acuosa |
CN103830197A (zh) * | 2014-03-14 | 2014-06-04 | 崔书豪 | 一种盐酸雷洛昔芬分散片及其制备方法 |
US9526734B2 (en) | 2014-06-09 | 2016-12-27 | Iceutica Pty Ltd. | Formulation of meloxicam |
KR102612983B1 (ko) * | 2016-09-30 | 2023-12-13 | 한미약품 주식회사 | 용출율이 향상된 라록시펜, 및 비타민 d 또는 그 유도체를 포함하는 복합 캡슐제 및 이의 제조방법 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
TW366342B (en) * | 1992-07-28 | 1999-08-11 | Lilly Co Eli | The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss |
-
1995
- 1995-02-23 CA CA002143263A patent/CA2143263C/en not_active Expired - Lifetime
- 1995-02-23 BR BR9500758A patent/BR9500758A/pt not_active Application Discontinuation
- 1995-02-23 ZA ZA951497A patent/ZA951497B/xx unknown
- 1995-02-23 IL IL11274695A patent/IL112746A/xx not_active IP Right Cessation
- 1995-02-24 RU RU95102924A patent/RU2118540C1/ru not_active IP Right Cessation
- 1995-02-24 CZ CZ1995499A patent/CZ286119B6/cs not_active IP Right Cessation
- 1995-02-27 CN CN95100822A patent/CN1098684C/zh not_active Expired - Lifetime
- 1995-02-28 ES ES95301291T patent/ES2166799T3/es not_active Expired - Lifetime
- 1995-02-28 DE DE69524981T patent/DE69524981T2/de not_active Expired - Lifetime
- 1995-02-28 EP EP95301291A patent/EP0670162B1/de not_active Expired - Lifetime
- 1995-02-28 SI SI9530581T patent/SI0670162T1/xx unknown
- 1995-02-28 NZ NZ270588A patent/NZ270588A/en unknown
- 1995-02-28 DK DK95301291T patent/DK0670162T3/da active
- 1995-02-28 AT AT95301291T patent/ATE211910T1/de active
- 1995-02-28 PT PT95301291T patent/PT670162E/pt unknown
- 1995-03-01 NO NO19950799A patent/NO314286B1/no not_active IP Right Cessation
- 1995-03-01 AU AU13548/95A patent/AU684882B2/en not_active Expired
- 1995-03-01 PL PL95307491A patent/PL178858B1/pl not_active IP Right Cessation
- 1995-03-01 JP JP4177395A patent/JP3574210B2/ja not_active Expired - Lifetime
- 1995-03-01 FI FI950947A patent/FI117042B/fi not_active IP Right Cessation
- 1995-03-01 HU HU9500635A patent/HU225418B1/hu not_active IP Right Cessation
-
1997
- 1997-01-30 SG SG1997000220A patent/SG65636A1/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69524981T2 (de) | Pharmazeutische Zubereitungen enthaltend Raloxifen, einen oberflächenaktiven Stoff und ein wasserlösliches Verdünnungsmittel | |
DK0698393T3 (da) | 3-/-menthoxypropan-1,2-diol som solubiliseringsmiddel og præparat til udvortes brug, der indeholder samme | |
GB2341801B (en) | Formulation | |
DK0399902T3 (da) | Porøs farmaceutisk tilberedningsform og fremstilling deraf | |
DK0642530T3 (da) | Dolastatinderivater | |
DK0482097T3 (da) | Tensidpræparater og fremgangsmåder | |
NO913035D0 (no) | (2r)-2-(di(2-propyl)fosfonylmetoksy)-3-p-toluensulfonyloksy-1-trimetylacetoksypropan, fremgangsmaate for fremstilling og anvendelse derav. | |
ATE149360T1 (de) | Zahnseide mit chemotherapeutischen wirkstoffen | |
SE9101687L (sv) | Dikloranilinfoerening | |
NO901169L (no) | Azol-1-alkanamider som anti-arrytmiske midler og fremstilling derav. | |
MY117590A (en) | Orally administerable pharmaceutical formulations | |
ITRM930085A0 (it) | Tensioattivi poco schiumogeni, loro preparazione e loro impiego in procedimenti di tintura. (caso 150-5603) | |
ITPR910054A0 (it) | Miscelatore per autorespiratore ad uso medicale,particolarmente per camera iperbarica. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336 |
|
8328 | Change in the person/name/address of the agent |
Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN |
|
R082 | Change of representative |
Ref document number: 670162 Country of ref document: EP Representative=s name: GRAF VON STOSCH PATENTANWALTSGESELLSCHAFT MBH, 805 |
|
R082 | Change of representative |
Ref document number: 670162 Country of ref document: EP Representative=s name: GRAF VON STOSCH PATENTANWALTSGESELLSCHAFT MBH, DE |
|
R081 | Change of applicant/patentee |
Ref document number: 670162 Country of ref document: EP Owner name: DAIICHI SANKYO EUROPE GMBH, DE Free format text: FORMER OWNER: ELI LILLY AND CO., INDIANAPOLIS, US Effective date: 20120918 |
|
R082 | Change of representative |
Ref document number: 670162 Country of ref document: EP Representative=s name: GRAF VON STOSCH PATENTANWALTSGESELLSCHAFT MBH, DE Effective date: 20120918 |