DE69523610T2 - Säule für kapillarchromatographische Trennverfahren - Google Patents

Säule für kapillarchromatographische Trennverfahren

Info

Publication number
DE69523610T2
DE69523610T2 DE69523610T DE69523610T DE69523610T2 DE 69523610 T2 DE69523610 T2 DE 69523610T2 DE 69523610 T DE69523610 T DE 69523610T DE 69523610 T DE69523610 T DE 69523610T DE 69523610 T2 DE69523610 T2 DE 69523610T2
Authority
DE
Germany
Prior art keywords
column
chromatographic separation
separation processes
capillary chromatographic
capillary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69523610T
Other languages
English (en)
Other versions
DE69523610D1 (de
Inventor
Monika Dittmann
Gerard Rozing
Hans-Peter Zimmermann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agilent Technologies Inc
Original Assignee
Agilent Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agilent Technologies Inc filed Critical Agilent Technologies Inc
Application granted granted Critical
Publication of DE69523610D1 publication Critical patent/DE69523610D1/de
Publication of DE69523610T2 publication Critical patent/DE69523610T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/603—Construction of the column end pieces retaining the stationary phase, e.g. Frits
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/28—Control of physical parameters of the fluid carrier
    • G01N2030/285—Control of physical parameters of the fluid carrier electrically driven carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6065—Construction of the column body with varying cross section
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6073—Construction of the column body in open tubular form
    • G01N30/6078—Capillaries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6082—Construction of the column body transparent to radiation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/74—Optical detectors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
DE69523610T 1995-12-14 1995-12-14 Säule für kapillarchromatographische Trennverfahren Expired - Fee Related DE69523610T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95119699A EP0779512B1 (de) 1995-12-14 1995-12-14 Säule für kapillarchromatographische Trennverfahren

Publications (2)

Publication Number Publication Date
DE69523610D1 DE69523610D1 (de) 2001-12-06
DE69523610T2 true DE69523610T2 (de) 2003-04-03

Family

ID=8219886

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69523610T Expired - Fee Related DE69523610T2 (de) 1995-12-14 1995-12-14 Säule für kapillarchromatographische Trennverfahren

Country Status (3)

Country Link
US (1) US5908552A (de)
EP (1) EP0779512B1 (de)
DE (1) DE69523610T2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112004000231B4 (de) 2003-02-07 2022-07-14 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) In situ-Fritte und Verfahren zum Herstellen einer Chromatographievorrichtung

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DE69321110T2 (de) * 1993-07-12 1999-03-04 Hewlett Packard Gmbh Verfahren zur Herstellung einer Kapillarrohres, Kapillarrohr für eine Elektrophoresevorrichtung und Elektrophoresevorrichtung mit einem solchen Kapillarrohr
US6136187A (en) * 1997-12-09 2000-10-24 The Board Of Trustees Of The Leland Stanford Junior University Separation column containing porous matrix and method of packing column
US6068767A (en) * 1998-10-29 2000-05-30 Sandia Corporation Device to improve detection in electro-chromatography
US6749814B1 (en) 1999-03-03 2004-06-15 Symyx Technologies, Inc. Chemical processing microsystems comprising parallel flow microreactors and methods for using same
CA2290731A1 (en) 1999-11-26 2001-05-26 D. Jed Harrison Apparatus and method for trapping bead based reagents within microfluidic analysis system
US6432290B1 (en) 1999-11-26 2002-08-13 The Governors Of The University Of Alberta Apparatus and method for trapping bead based reagents within microfluidic analysis systems
US6267884B1 (en) * 2000-01-04 2001-07-31 Waters Investments Limited Capillary columns employing monodispersed particles
EP1126275A3 (de) 2000-02-18 2002-12-18 The Board Of Trustees Of The Leland Stanford Junior University Kapillarsäule aus geschmolzenem Siliziumdioxid mit Photopolymerbestandteilen
US6875348B2 (en) 2000-02-18 2005-04-05 The Board Of Trustees Of The Leland Stanford Junior University Separation column having a photopolymerized sol-gel component and associated methods
US6866785B2 (en) 2001-08-13 2005-03-15 The Board Of Trustees Of The Leland Stanford Junior University Photopolymerized sol-gel column and associated methods
FR2808089B1 (fr) * 2000-04-25 2002-07-05 Sebia Sa Dispositif perfectionne d'analyse d'echantillons par electrophorese multicapillaire a thermo-regulation solide/solide
US20020176800A1 (en) * 2001-05-09 2002-11-28 Henry Richard A. Curved miniature liquid chromatography column
US20030108664A1 (en) * 2001-10-05 2003-06-12 Kodas Toivo T. Methods and compositions for the formation of recessed electrical features on a substrate
US20030217923A1 (en) * 2002-05-24 2003-11-27 Harrison D. Jed Apparatus and method for trapping bead based reagents within microfluidic analysis systems
KR20050088476A (ko) 2002-12-30 2005-09-06 더 리전트 오브 더 유니버시티 오브 캘리포니아 병원균 검출과 분석을 위한 방법과 기구
JP4931584B2 (ja) * 2003-07-14 2012-05-16 ウオーターズ・テクノロジーズ・コーポレイシヨン 一体型ガードカラムをもつ分離装置
US7799553B2 (en) * 2004-06-01 2010-09-21 The Regents Of The University Of California Microfabricated integrated DNA analysis system
US20070248958A1 (en) 2004-09-15 2007-10-25 Microchip Biotechnologies, Inc. Microfluidic devices
US7749365B2 (en) 2006-02-01 2010-07-06 IntegenX, Inc. Optimized sample injection structures in microfluidic separations
CA2641271A1 (en) 2006-02-03 2008-03-13 Microchip Biotechnologies, Inc. Microfluidic devices
WO2007104354A1 (en) * 2006-03-13 2007-09-20 Agilent Technologies, Inc Elastic porous column material
US7766033B2 (en) * 2006-03-22 2010-08-03 The Regents Of The University Of California Multiplexed latching valves for microfluidic devices and processors
EP1879026A1 (de) * 2006-06-24 2008-01-16 Agilent Technologies, Inc. Fokussierung einer Probe auf einer analytischen Säule
EP2044427A1 (de) 2006-07-17 2009-04-08 Agilent Technologies, Inc. Äquilibrierung eines temperaturprofils in einer säule
WO2008009311A1 (en) * 2006-07-17 2008-01-24 Agilent Technologies, Inc. Temperature adjustment of a fluidic sample within a fluidic device
EP1916522A1 (de) * 2006-10-25 2008-04-30 Agilent Technologies, Inc. Säule mit getrennten Abschnitten stationärer Phase
WO2008052138A2 (en) * 2006-10-25 2008-05-02 The Regents Of The University Of California Inline-injection microdevice and microfabricated integrated dna analysis system using same
KR20100028526A (ko) 2007-02-05 2010-03-12 마이크로칩 바이오테크놀로지스, 인크. 마이크로유체 및 나노유체 장치, 시스템 및 응용
WO2009108260A2 (en) 2008-01-22 2009-09-03 Microchip Biotechnologies, Inc. Universal sample preparation system and use in an integrated analysis system
DE102008012798A1 (de) * 2008-03-05 2009-09-10 Dionex Softron Gmbh Kapillarartige Verbindung für die Flüssigkeitschromatographie, insbesondere für die Hochleistungsflüssigkeitschromatographie mit verminderter Dispersion und verbesserten thermischen Eigenschaften
WO2009132330A2 (en) * 2008-04-25 2009-10-29 Biotrove, Inc. Separation cartridges and methods for fabrication and use thereof
EP2384429A1 (de) 2008-12-31 2011-11-09 Integenx Inc. Instrument mit mikrofluidischem chip
CN102459565A (zh) 2009-06-02 2012-05-16 尹特根埃克斯有限公司 具有隔膜阀的流控设备
RU2559541C2 (ru) 2009-06-05 2015-08-10 Интедженкс Инк. Универсальная система подготовки образцов и применение в интегрированной системе анализа
US8584703B2 (en) 2009-12-01 2013-11-19 Integenx Inc. Device with diaphragm valve
US8512538B2 (en) 2010-05-28 2013-08-20 Integenx Inc. Capillary electrophoresis device
EP2606154B1 (de) 2010-08-20 2019-09-25 Integenx Inc. Integriertes analysesystem
US8763642B2 (en) 2010-08-20 2014-07-01 Integenx Inc. Microfluidic devices with mechanically-sealed diaphragm valves
US20150136604A1 (en) 2011-10-21 2015-05-21 Integenx Inc. Sample preparation, processing and analysis systems
US10865440B2 (en) 2011-10-21 2020-12-15 IntegenX, Inc. Sample preparation, processing and analysis systems
US10073068B2 (en) 2013-09-18 2018-09-11 Agilent Technologies, Inc. Liquid chromatography columns with structured walls
WO2015073999A1 (en) 2013-11-18 2015-05-21 Integenx Inc. Cartridges and instruments for sample analysis
US10208332B2 (en) 2014-05-21 2019-02-19 Integenx Inc. Fluidic cartridge with valve mechanism
CN113092563B (zh) 2014-10-22 2024-06-07 尹特根埃克斯有限公司 用于样品制备、处理和分析的系统和方法
GB201819984D0 (en) * 2018-12-07 2019-01-23 Ge Healthcare Bio Sciences Ab Chromatography column and method of assembling the same
BE1027013B1 (nl) * 2019-01-31 2020-09-01 Pharmafluidics N V Filter voor chemische reactoren

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US3782078A (en) * 1972-02-14 1974-01-01 J Jerpe Apparatus for chromatographic separations
US4293415A (en) * 1979-04-27 1981-10-06 Hewlett-Packard Company Silica chromatographic column
US4793920A (en) * 1985-12-11 1988-12-27 Lee Scientific, Inc. Chromatography columns with cast porous plugs and methods of fabricating same
DE68924284T2 (de) * 1988-02-12 1996-02-29 Perkin Elmer Corp Säule für Hochdruck-Flüssigkeitschromatographie.
US5061361A (en) * 1989-03-06 1991-10-29 Hewlett-Packard Company Capillary zone electrophoresis cell system
US5246577A (en) * 1990-05-29 1993-09-21 Millipore Corporation Apparatus for effecting capillary electrophoresis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112004000231B4 (de) 2003-02-07 2022-07-14 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) In situ-Fritte und Verfahren zum Herstellen einer Chromatographievorrichtung

Also Published As

Publication number Publication date
US5908552A (en) 1999-06-01
EP0779512B1 (de) 2001-10-31
EP0779512A1 (de) 1997-06-18
DE69523610D1 (de) 2001-12-06

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Legal Events

Date Code Title Description
8332 No legal effect for de
8327 Change in the person/name/address of the patent owner

Owner name: AGILENT TECHNOLOGIES, INC. (N.D.GES.D.STAATES DELA

8370 Indication of lapse of patent is to be deleted
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AGILENT TECHNOLOGIES, INC. (N.D.GES.D. STAATES, US

8339 Ceased/non-payment of the annual fee