DE69521104T2 - Spezifische Bindungstests und Reagenzien dafür - Google Patents

Spezifische Bindungstests und Reagenzien dafür

Info

Publication number
DE69521104T2
DE69521104T2 DE69521104T DE69521104T DE69521104T2 DE 69521104 T2 DE69521104 T2 DE 69521104T2 DE 69521104 T DE69521104 T DE 69521104T DE 69521104 T DE69521104 T DE 69521104T DE 69521104 T2 DE69521104 T2 DE 69521104T2
Authority
DE
Germany
Prior art keywords
specific binding
analyte
binding tests
amount
assay
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69521104T
Other languages
English (en)
Other versions
DE69521104D1 (de
Inventor
David Kiaei
Laurie Ann Livshin
Uri Piran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Publication of DE69521104D1 publication Critical patent/DE69521104D1/de
Application granted granted Critical
Publication of DE69521104T2 publication Critical patent/DE69521104T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125—Digestion or removing interfering materials
DE69521104T 1994-11-15 1995-11-13 Spezifische Bindungstests und Reagenzien dafür Expired - Fee Related DE69521104T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/339,870 US5639626A (en) 1994-11-15 1994-11-15 Reagents for specific binding assays

Publications (2)

Publication Number Publication Date
DE69521104D1 DE69521104D1 (de) 2001-07-05
DE69521104T2 true DE69521104T2 (de) 2001-09-13

Family

ID=23330986

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69521104T Expired - Fee Related DE69521104T2 (de) 1994-11-15 1995-11-13 Spezifische Bindungstests und Reagenzien dafür

Country Status (9)

Country Link
US (2) US5639626A (de)
EP (2) EP1085322A1 (de)
JP (1) JPH08240590A (de)
KR (1) KR960018584A (de)
AT (1) ATE201771T1 (de)
AU (1) AU713482B2 (de)
CA (1) CA2151197A1 (de)
DE (1) DE69521104T2 (de)
PL (1) PL178150B1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10211818A1 (de) * 2002-03-16 2003-10-09 Pe Diagnostik Gmbh Verfahren zur quantitativen Bestimmung mehrerer Analyten

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050069923A1 (en) * 1996-07-08 2005-03-31 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
US5895765A (en) * 1997-06-30 1999-04-20 Bayer Corporation Method for the detection of an analyte by immunochromatography
DE19748489A1 (de) 1997-11-03 1999-05-06 Roche Diagnostics Gmbh Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
JPH11287802A (ja) * 1998-04-03 1999-10-19 Nippon Kayaku Co Ltd 表面保護剤
US6379909B1 (en) * 1998-06-24 2002-04-30 Alk-Abello A/S Method of detecting an antibody in a liquid sample
US6194224B1 (en) 1998-07-27 2001-02-27 Avitar, Inc. Diagnostic membrane containing fatty acid sarcosinate surfactant for testing oral fluid
DE60017017T2 (de) 1999-01-27 2006-04-13 Bayer Corp. Immuntest unter verwendung von partikeln mit kaseinumhüllungen
AU4289799A (en) * 1999-06-25 2001-01-31 Kyowa Medex Co., Ltd. Immunoassay supports and immunoasssay solid phases with the use thereof
US6743585B2 (en) 1999-09-16 2004-06-01 Agilent Technologies, Inc. Methods for preparing conjugates
WO2002027316A2 (en) * 2000-09-25 2002-04-04 Abbott Laboratories Methods and kits for decreasing interferences of assays samples containing plasma or serum in specific binding assays by using a large polycation
US20040248093A1 (en) * 2000-11-27 2004-12-09 Coombs James Howard Magneto-optical bio-discs and systems including related methods
US20030003464A1 (en) * 2000-11-27 2003-01-02 Phan Brigitte C. Dual bead assays including optical biodiscs and methods relating thereto
US20020172980A1 (en) * 2000-11-27 2002-11-21 Phan Brigitte Chau Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems
US7501157B2 (en) * 2001-06-26 2009-03-10 Accelr8 Technology Corporation Hydroxyl functional surface coating
US6844028B2 (en) * 2001-06-26 2005-01-18 Accelr8 Technology Corporation Functional surface coating
US20050233473A1 (en) * 2002-08-16 2005-10-20 Zyomyx, Inc. Methods and reagents for surface functionalization
EP1681568A1 (de) * 2003-10-29 2006-07-19 Hidechika Okada Künstlicher antikörper mit komplementärem peptid
WO2005094381A2 (en) * 2004-04-01 2005-10-13 Rules-Based Medicine, Inc. Universal shotgun assay
US7618777B2 (en) * 2005-03-16 2009-11-17 Agilent Technologies, Inc. Composition and method for array hybridization
JP4697944B2 (ja) * 2005-06-10 2011-06-08 キヤノン株式会社 非特異吸着を低減するプローブ固定担体の製造方法
FR2888937B1 (fr) 2005-07-21 2012-10-26 Biomerieux Sa Procede de detection des fcpa utilisant un agent d'agregation des fcpa et un agent de capture des agregats formes
US20080108147A1 (en) * 2006-11-03 2008-05-08 Tie Wei Reduction of non-specific binding in immunoassays
US20080207960A1 (en) * 2007-02-28 2008-08-28 Eric Lin Methods, compositions, and kits for post-hybridization processing of arrays
US8617820B2 (en) * 2007-08-28 2013-12-31 Ortho-Clinical Diagnostics, Inc. Use of glycosaminoglycans to reduce non-specific binding in immunoassays
WO2009137713A2 (en) * 2008-05-07 2009-11-12 The Regents Of The University Of California Particle-based electrostatic sensing and detection
US10267789B2 (en) * 2010-03-31 2019-04-23 Sekisui Medical Co., Ltd. Method of reducing interference from component outside of measurement system
WO2016191603A1 (en) * 2015-05-26 2016-12-01 OncoGenesis Inc. System, method and kit for detection of analytes by production of electrochemical species
EP3574324A2 (de) 2017-01-27 2019-12-04 Roche Diagnostics GmbH Verfahren zur modulierung der signalintensität in interaktionsassays
CN112129946A (zh) * 2020-08-16 2020-12-25 陆修委 无糖链型惰性蛋白封闭剂的制备方法及应用
CN116027019B (zh) * 2022-12-23 2023-10-03 宁波瑞源生物科技有限公司 一种用于化学发光免疫分析的添加剂及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281061A (en) * 1979-07-27 1981-07-28 Syva Company Double antibody for enhanced sensitivity in immunoassay
GB8317855D0 (en) * 1983-06-30 1983-08-03 Iq Bio Ltd Biochemical detection method
DE3327642A1 (de) * 1983-07-30 1985-02-14 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung eines partners einer immunreaktion sowie reagens zur durchfuehrung dieses verfahrens
US4689309A (en) * 1985-09-30 1987-08-25 Miles Laboratories, Inc. Test device, method of manufacturing same and method of determining a component in a sample
US4810630A (en) * 1987-03-30 1989-03-07 E. I. Du Pont De Nemours And Company Use of polyoxyethylene ethers to improve the performance of immunoassays employing peroxidase conjugates
US4971904A (en) * 1987-06-26 1990-11-20 E. I. Du Pont De Nemours And Company Heterogeneous immunoassay
US4927769A (en) * 1987-07-08 1990-05-22 Ciba Corning Diagnostics Corp. Method for enhancement of chemiluminescence
US5124245A (en) * 1989-02-09 1992-06-23 Eastman Kodak Company Wash composition, test kit and their use to determine a herpes simplex viral antigen
DE4023671A1 (de) * 1990-07-25 1992-01-30 Boehringer Mannheim Gmbh Nichtionische blockcopolymere aus propylenoxid und ethylenoxid
JP3076640B2 (ja) * 1991-07-26 2000-08-14 富士薬品工業株式会社 ヒト９２ｋＤａゼラチナーゼの免疫学的定量法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10211818A1 (de) * 2002-03-16 2003-10-09 Pe Diagnostik Gmbh Verfahren zur quantitativen Bestimmung mehrerer Analyten
DE10211818B4 (de) * 2002-03-16 2006-07-06 peS Gesellschaft für medizinische Diagnose-Systeme mbH Verfahren zur quantitativen Bestimmung mehrerer Analyten

Also Published As

Publication number Publication date
EP0713095A3 (de) 1996-07-31
US5710006A (en) 1998-01-20
PL178150B1 (pl) 2000-03-31
EP0713095A2 (de) 1996-05-22
AU2044795A (en) 1996-05-23
AU713482B2 (en) 1999-12-02
EP1085322A1 (de) 2001-03-21
JPH08240590A (ja) 1996-09-17
DE69521104D1 (de) 2001-07-05
KR960018584A (ko) 1996-06-17
US5639626A (en) 1997-06-17
EP0713095B1 (de) 2001-05-30
CA2151197A1 (en) 1996-05-16
ATE201771T1 (de) 2001-06-15
PL309211A1 (en) 1996-05-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee