DE69518246D1 - Aminosäuren konjugaten - Google Patents
Aminosäuren konjugatenInfo
- Publication number
- DE69518246D1 DE69518246D1 DE69518246T DE69518246T DE69518246D1 DE 69518246 D1 DE69518246 D1 DE 69518246D1 DE 69518246 T DE69518246 T DE 69518246T DE 69518246 T DE69518246 T DE 69518246T DE 69518246 D1 DE69518246 D1 DE 69518246D1
- Authority
- DE
- Germany
- Prior art keywords
- alpha
- pct
- date
- amino acid
- acceptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000001413 amino acids Chemical class 0.000 title 1
- OVRNDRQMDRJTHS-KEWYIRBNSA-N N-acetyl-D-galactosamine Chemical compound CC(=O)N[C@H]1C(O)O[C@H](CO)[C@H](O)[C@@H]1O OVRNDRQMDRJTHS-KEWYIRBNSA-N 0.000 abstract 2
- MBLBDJOUHNCFQT-UHFFFAOYSA-N N-acetyl-D-galactosamine Natural products CC(=O)NC(C=O)C(O)C(O)C(O)CO MBLBDJOUHNCFQT-UHFFFAOYSA-N 0.000 abstract 2
- 239000004473 Threonine Substances 0.000 abstract 2
- MQWZJOSNNICZJE-JRTVQGFMSA-N (2r,3s,4s,5s)-5-acetamido-2,3,4-trihydroxy-6-oxohexanoic acid Chemical compound CC(=O)N[C@H](C=O)[C@H](O)[C@H](O)[C@@H](O)C(O)=O MQWZJOSNNICZJE-JRTVQGFMSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 102000002014 alpha-N-Acetylgalactosaminidase Human genes 0.000 abstract 1
- 108010015684 alpha-N-Acetylgalactosaminidase Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000003355 serines Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 238000005918 transglycosylation reaction Methods 0.000 abstract 1
- 150000008135 α-glycosides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
Landscapes
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Peptides Or Proteins (AREA)
- Polyamides (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9403011A SE9403011D0 (sv) | 1994-09-06 | 1994-09-06 | Aminosockerkonjugat |
| SE9502159A SE9502159D0 (sv) | 1995-06-10 | 1995-06-10 | Aminoacid conjugate |
| PCT/IB1995/000740 WO1996007753A1 (en) | 1994-09-06 | 1995-09-06 | Amino acid conjugate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69518246D1 true DE69518246D1 (de) | 2000-09-07 |
| DE69518246T2 DE69518246T2 (de) | 2000-12-21 |
Family
ID=26662133
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69518246T Expired - Lifetime DE69518246T2 (de) | 1994-09-06 | 1995-09-06 | Aminosäuren konjugaten |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5882902A (de) |
| EP (1) | EP0779932B1 (de) |
| AT (1) | ATE195147T1 (de) |
| AU (1) | AU3264195A (de) |
| DE (1) | DE69518246T2 (de) |
| WO (1) | WO1996007753A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9904695D0 (en) * | 1999-03-01 | 1999-04-21 | Imp Cancer Res Tech | Peptide |
| JP2002176998A (ja) * | 2000-12-15 | 2002-06-25 | Meiji Milk Prod Co Ltd | ムチン型糖ペプチドおよび糖タンパク質製造法 |
| WO2004013151A2 (en) * | 2002-08-01 | 2004-02-12 | National Research Council Of Canada | Campylobacter glycans and glycopeptides |
| US20050053900A1 (en) * | 2003-09-05 | 2005-03-10 | Steven Kaufmann | Method of teaching a foreign language to a student providing measurement in a context based learning system |
| WO2005111225A1 (en) * | 2004-05-04 | 2005-11-24 | Novo Nordisk Health Care Ag | O-linked glycoforms of polypeptides and method to manufacture them |
| US7625552B2 (en) * | 2006-05-30 | 2009-12-01 | Boston Scientific Scimed, Inc. | Bioactive polymers for imparting bioactive character to hydrophobic medical article surfaces |
| US9051593B2 (en) | 2009-12-21 | 2015-06-09 | Trustees Of Dartmouth College | Recombinant prokaryotes and use thereof for production of O-glycosylated proteins |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE451849B (sv) * | 1985-12-11 | 1987-11-02 | Svenska Sockerfabriks Ab | Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter |
| US5583042A (en) * | 1990-04-16 | 1996-12-10 | Neose Pharmaceuticals, Inc. | Apparatus for the synthesis of saccharide compositions |
| DE4013077A1 (de) * | 1990-04-25 | 1991-10-31 | Hoechst Ag | Verfahren zur glycosidasekatalysierten synthese von glycokonjugaten |
| SE9102292L (sv) * | 1991-08-06 | 1993-02-07 | Kurt G I Nilsson | Enzymatisk metod |
| EP0551107A2 (de) * | 1992-01-09 | 1993-07-14 | Hoechst Aktiengesellschaft | Verfahren zur beta-Galactosidase-katalysierten Transglycosidierung mit unphysiologischen Glycosyldonoren |
| SE9304316D0 (sv) * | 1993-12-24 | 1993-12-24 | Kurt Nilsson | Aminosyra-konjugat |
-
1995
- 1995-09-06 AT AT95929186T patent/ATE195147T1/de not_active IP Right Cessation
- 1995-09-06 WO PCT/IB1995/000740 patent/WO1996007753A1/en active IP Right Grant
- 1995-09-06 EP EP95929186A patent/EP0779932B1/de not_active Expired - Lifetime
- 1995-09-06 US US08/793,876 patent/US5882902A/en not_active Expired - Fee Related
- 1995-09-06 DE DE69518246T patent/DE69518246T2/de not_active Expired - Lifetime
- 1995-09-06 AU AU32641/95A patent/AU3264195A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0779932B1 (de) | 2000-08-02 |
| EP0779932A1 (de) | 1997-06-25 |
| DE69518246T2 (de) | 2000-12-21 |
| WO1996007753A1 (en) | 1996-03-14 |
| US5882902A (en) | 1999-03-16 |
| ATE195147T1 (de) | 2000-08-15 |
| AU3264195A (en) | 1996-03-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: GLYCOREX TRANSPLANTATION AB (PUBL), LUND, SE |
|
| 8381 | Inventor (new situation) |
Inventor name: NILSSON, KURT, LUND, SE |