DE69515922T2 - Analogen von Acronycine, Verfahren zu ihrer Herstellung und sie enthaltende pharmaceutische Zusammensetzungen - Google Patents

Analogen von Acronycine, Verfahren zu ihrer Herstellung und sie enthaltende pharmaceutische Zusammensetzungen

Info

Publication number
DE69515922T2
DE69515922T2 DE69515922T DE69515922T DE69515922T2 DE 69515922 T2 DE69515922 T2 DE 69515922T2 DE 69515922 T DE69515922 T DE 69515922T DE 69515922 T DE69515922 T DE 69515922T DE 69515922 T2 DE69515922 T2 DE 69515922T2
Authority
DE
Germany
Prior art keywords
alkoxy
acronycine
analogues
acyl
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69515922T
Other languages
English (en)
Other versions
DE69515922D1 (de
Inventor
Michel Koch
Francois Tillequin
Alexios-Leandros Skaltsounis
Yves Rolland
Alain Pierre
Ghanem Atassi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Servier SAS
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Application granted granted Critical
Publication of DE69515922D1 publication Critical patent/DE69515922D1/de
Publication of DE69515922T2 publication Critical patent/DE69515922T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
DE69515922T 1994-02-17 1995-02-15 Analogen von Acronycine, Verfahren zu ihrer Herstellung und sie enthaltende pharmaceutische Zusammensetzungen Expired - Fee Related DE69515922T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9401806A FR2716197B1 (fr) 1994-02-17 1994-02-17 Nouveaux analogues de l'acronycine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number Publication Date
DE69515922D1 DE69515922D1 (de) 2000-05-04
DE69515922T2 true DE69515922T2 (de) 2000-11-02

Family

ID=9460176

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69515922T Expired - Fee Related DE69515922T2 (de) 1994-02-17 1995-02-15 Analogen von Acronycine, Verfahren zu ihrer Herstellung und sie enthaltende pharmaceutische Zusammensetzungen

Country Status (17)

Country Link
US (1) US5567707A (de)
EP (1) EP0668281B1 (de)
JP (1) JP2675271B2 (de)
CN (1) CN1055926C (de)
AT (1) ATE191216T1 (de)
AU (1) AU680080B2 (de)
CA (1) CA2142560C (de)
DE (1) DE69515922T2 (de)
DK (1) DK0668281T3 (de)
ES (1) ES2146722T3 (de)
FI (1) FI118767B (de)
FR (1) FR2716197B1 (de)
GR (1) GR3033003T3 (de)
NO (1) NO308472B1 (de)
NZ (1) NZ270509A (de)
PT (1) PT668281E (de)
ZA (1) ZA951334B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130161A (en) 1997-05-30 2000-10-10 International Business Machines Corporation Method of forming copper interconnections with enhanced electromigration resistance and reduced defect sensitivity
FR2772765B1 (fr) * 1997-12-19 2000-03-17 Adir Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2856687B1 (fr) * 2003-06-25 2005-09-16 Servier Lab Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2902792A1 (fr) * 2006-06-21 2007-12-28 Servier Lab Nouveaux derives cinnamates de tetrahydro-7h-pyrano(2,3-c)acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3624087A (en) * 1967-07-17 1971-11-30 Lilly Co Eli Synthesis of acronycine and related compounds
US3621041A (en) * 1968-07-05 1971-11-16 Lilly Co Eli Chromans
US3673163A (en) * 1970-06-16 1972-06-27 Lilly Co Eli Pharmacological preparation containing an acronycine-polyvinylprrolidone coprecipitate
US3657249A (en) * 1970-10-12 1972-04-18 Lilly Co Eli Synthesis of nordihydroacronycine and related compounds
US3715359A (en) * 1971-07-02 1973-02-06 Lilly Co Eli Hydroxylated acronycine
US3943137A (en) * 1973-07-09 1976-03-09 University Of Kansas Endowment Association Acronycine derivatives

Also Published As

Publication number Publication date
US5567707A (en) 1996-10-22
CN1055926C (zh) 2000-08-30
NZ270509A (en) 1996-03-26
EP0668281A1 (de) 1995-08-23
CA2142560C (fr) 2002-04-09
PT668281E (pt) 2000-07-31
DE69515922D1 (de) 2000-05-04
CA2142560A1 (fr) 1995-08-18
CN1113490A (zh) 1995-12-20
FR2716197A1 (fr) 1995-08-18
JP2675271B2 (ja) 1997-11-12
AU1228795A (en) 1995-08-24
NO308472B1 (no) 2000-09-18
FI950681A (fi) 1995-08-18
NO950574D0 (no) 1995-02-16
EP0668281B1 (de) 2000-03-29
ES2146722T3 (es) 2000-08-16
NO950574L (no) 1995-08-18
ZA951334B (en) 1995-10-23
FI950681A0 (fi) 1995-02-15
FR2716197B1 (fr) 1996-04-19
AU680080B2 (en) 1997-07-17
FI118767B (fi) 2008-03-14
DK0668281T3 (da) 2000-08-14
GR3033003T3 (en) 2000-07-31
JPH07252257A (ja) 1995-10-03
ATE191216T1 (de) 2000-04-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LES LABORATOIRES SERVIER, NEUILLY SUR SEINE, FR

8339 Ceased/non-payment of the annual fee