DE69433115D1 - Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien - Google Patents

Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien

Info

Publication number
DE69433115D1
DE69433115D1 DE69433115T DE69433115T DE69433115D1 DE 69433115 D1 DE69433115 D1 DE 69433115D1 DE 69433115 T DE69433115 T DE 69433115T DE 69433115 T DE69433115 T DE 69433115T DE 69433115 D1 DE69433115 D1 DE 69433115D1
Authority
DE
Germany
Prior art keywords
presented
methods
antigens
antigen
isolating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69433115T
Other languages
English (en)
Other versions
DE69433115T2 (de
Inventor
Steven A Porcelli
Michael B Brenner
Evan Beckman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Original Assignee
Brigham and Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc filed Critical Brigham and Womens Hospital Inc
Application granted granted Critical
Publication of DE69433115D1 publication Critical patent/DE69433115D1/de
Publication of DE69433115T2 publication Critical patent/DE69433115T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69433115T 1993-06-21 1994-06-21 Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien Expired - Fee Related DE69433115T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8007293A 1993-06-21 1993-06-21
US80072 1993-06-21
PCT/US1994/006991 WO1995000163A1 (en) 1993-06-21 1994-06-21 Methods of isolating cd1-presented antigens, vaccines comprising cd1-presented antigens, and cell lines for use in said methods

Publications (2)

Publication Number Publication Date
DE69433115D1 true DE69433115D1 (de) 2003-10-09
DE69433115T2 DE69433115T2 (de) 2004-04-01

Family

ID=22155084

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69433115T Expired - Fee Related DE69433115T2 (de) 1993-06-21 1994-06-21 Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien

Country Status (8)

Country Link
EP (1) EP0751780B1 (de)
JP (2) JPH08511939A (de)
AT (1) ATE248602T1 (de)
CA (1) CA2165786A1 (de)
DE (1) DE69433115T2 (de)
DK (1) DK0751780T3 (de)
ES (1) ES2201078T3 (de)
WO (1) WO1995000163A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6238676B1 (en) 1992-12-10 2001-05-29 Brigham And Women's Hospital Presentation of hydrophobic antigens to T-cells by CD1 molecules
US7063844B2 (en) 1992-12-10 2006-06-20 The Brigham And Women's Hospital, Inc. Presentation of hydrophobic antigens to T-cells by CD1 molecules
WO1995028642A1 (en) 1994-04-14 1995-10-26 Brown, Keith, Edwin, Frank A method for detecting the presence of a mycobacterium species and a kit and antibodies for use therein
ATE212129T1 (de) * 1994-10-13 2002-02-15 Brigham & Womens Hospital Präsentation von aus lipoarabinomannan bestehenden antigenen an t-zellen durch cd1 moleküle
JPH11500906A (ja) * 1995-02-22 1999-01-26 アドコック、イングラム、リミテッド 脂質細胞壁成分の単離および精製法
DK0879282T3 (da) * 1996-01-17 2003-10-20 Imp College Innovations Ltd Immunterapi ved anvendelse af cytotoksiske T-lymfocytter (CTL)
ATE402413T1 (de) 1997-03-03 2008-08-15 Adcock Ingram Ltd Eine zusammensetzung, die eine trägerkomponente und eine gereinigte mykobakterielle zellwandkomponente enthält, und ihre verwendung zur verhinderung, behandlung und diagnose von erkrankungen
US7419958B2 (en) 2001-03-26 2008-09-02 Dana-Farber Cancer Institute, Inc. Method of attenuating reactions to skin irritants
US7253159B2 (en) 2003-04-18 2007-08-07 The Brigham And Women's Hospital, Inc. Methods and compositions for immunomodulation using CD1 antigens
WO2006060117A2 (en) 2004-11-02 2006-06-08 The Board Of Trustees Of The Leland Stanford Junior University Methods for inhibition of nkt cells
EP2047860A1 (de) * 2007-10-12 2009-04-15 Centre National De La Recherche Scientifique (Cnrs) Pharmazeutische Zusammensetzungen mit Actinomycet-Glycerin-Acyl-Derivat-Antigenen, Verfahren zu deren Extraktion und ihre Verwendung gegen Tuberkulose
US12077586B2 (en) 2018-09-19 2024-09-03 LAVA Therapeutics N.V. Bispecific antibodies for use in the treatment of hematological malignancies

Also Published As

Publication number Publication date
DE69433115T2 (de) 2004-04-01
EP0751780A1 (de) 1997-01-08
ATE248602T1 (de) 2003-09-15
EP0751780B1 (de) 2003-09-03
ES2201078T3 (es) 2004-03-16
WO1995000163A1 (en) 1995-01-05
CA2165786A1 (en) 1995-01-05
JP2006104206A (ja) 2006-04-20
JPH08511939A (ja) 1996-12-17
EP0751780A4 (de) 1997-12-10
DK0751780T3 (da) 2003-10-13

Similar Documents

Publication Publication Date Title
DE69433115D1 (de) Verfahren zur isolierung von cda-präsentierten antigenen, cd1-präsentierte antigeneenthaltende impfstoffe und in besagten verfahren verwendbare zelllinien
DE69333289D1 (de) Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien
DK0941478T3 (da) Assaymetode for peptidspecifikke T-celler
MX9801687A (es) Compuestos y metodos para el diagnostico de tuberculosis.
NO164866C (no) Reagens og forsoeksinnretning til bestemmelse av tilstedevaerelsen av leukocytter, esterase og protease i en proeve.
TR199802082T2 (xx) Otoantigen ve otoim�n hastal�klar�n im�noterapisinde kullan�lmak i�in otoantigen yap�sal olarak ili�kili proteinler.
Buchanan et al. Activation of the cell wall degrading protease, lysin, during sexual signalling in Chlamydomonas: the enzyme is stored as an inactive, higher relative molecular mass precursor in the periplasm.
ES2130672T3 (es) Nuevos peptidos derivados de un antigeno y destinados para la inmunoterapia de las enfermedades autoinmunes.
KR950008537A (ko) 엡스타인 바 비루스(ebv)에 대한 항체의 검출용 진단제
DE69833660D1 (de) Nukleinsäuresonden zur detektion von candida-spezies
DK0755517T3 (da) Fremgangsmåde til detektion af tilstedeværelse af en Mycobacterium-art og et kit og antistoffer til anvendelse i denne
DE69330164D1 (de) Htlv-i/htlv-ii assay und verfahren
DE69525058D1 (de) Präsentation von aus lipoarabinomannan bestehenden antigenen an t-zellen durch cd1 moleküle
SE9602677D0 (sv) Methods for determining brain antigens
ATE192236T1 (de) Menschliche phospholipase aktivierender proteinteil
Vendrell et al. In vitro antibody secretion by peripheral blood mononuclear cells as an expression of the immune response to Brucella spp. in humans

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee