DE69431665D1 - Peptide zum induzieren einer antwort der zytotoxischen t-lymphozythen gerichetetgegen das hepatitis b-virus - Google Patents
Peptide zum induzieren einer antwort der zytotoxischen t-lymphozythen gerichetetgegen das hepatitis b-virusInfo
- Publication number
- DE69431665D1 DE69431665D1 DE69431665T DE69431665T DE69431665D1 DE 69431665 D1 DE69431665 D1 DE 69431665D1 DE 69431665 T DE69431665 T DE 69431665T DE 69431665 T DE69431665 T DE 69431665T DE 69431665 D1 DE69431665 D1 DE 69431665D1
- Authority
- DE
- Germany
- Prior art keywords
- peptides
- virus
- cytotoxic
- hepatitis
- lymphocythes
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 241000700721 Hepatitis B virus Species 0.000 title abstract 2
- 231100000433 cytotoxic Toxicity 0.000 title 1
- 230000001472 cytotoxic effect Effects 0.000 title 1
- 230000001939 inductive effect Effects 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 108700024845 Hepatitis B virus P Proteins 0.000 abstract 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10087093A | 1993-08-02 | 1993-08-02 | |
| PCT/US1994/008685 WO1995003777A1 (en) | 1993-08-02 | 1994-08-01 | Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69431665D1 true DE69431665D1 (de) | 2002-12-12 |
| DE69431665T2 DE69431665T2 (de) | 2003-08-21 |
Family
ID=22281958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69431665T Expired - Lifetime DE69431665T2 (de) | 1993-08-02 | 1994-08-01 | Peptide zum induzieren einer antwort der zytotoxischen t-lymphozythen gerichetetgegen das hepatitis b-virus |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0726758B1 (de) |
| JP (2) | JP3650110B2 (de) |
| AT (1) | ATE227118T1 (de) |
| AU (1) | AU702367B2 (de) |
| CA (1) | CA2168583C (de) |
| DE (1) | DE69431665T2 (de) |
| DK (1) | DK0726758T3 (de) |
| ES (1) | ES2187530T3 (de) |
| NZ (1) | NZ271531A (de) |
| PT (1) | PT726758E (de) |
| WO (1) | WO1995003777A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6607727B1 (en) | 1991-08-26 | 2003-08-19 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus |
| US7611713B2 (en) | 1993-03-05 | 2009-11-03 | Pharmexa Inc. | Inducing cellular immune responses to hepatitis B virus using peptide compositions |
| US6689363B1 (en) | 1992-01-29 | 2004-02-10 | Epimmune Inc. | Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions |
| US6235288B1 (en) | 1992-08-26 | 2001-05-22 | The Scripps Research Institute | Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus |
| US5858689A (en) * | 1993-07-22 | 1999-01-12 | Ludwig Institute For Cancer Research | Isolated peptides derived from the gage tumor rejection antigen precursor and uses thereof |
| JP2001504799A (ja) * | 1996-03-11 | 2001-04-10 | エピミューン インコーポレイテッド | Ｈｌａ分子への結合アフィニティーが増加したペプチド |
| EP1049711B1 (de) * | 1998-01-19 | 2003-12-10 | Mogam Biotechnology Research Institute | Liposomen, enthaltend peptidantigene, welche vom x-protein aus hepatitis b virus abstammen |
| ATE512666T1 (de) * | 1999-06-29 | 2011-07-15 | Epimmune Inc | Hla-bindende peptide und ihre verwendungen |
| JP2004517609A (ja) * | 2000-09-01 | 2004-06-17 | エピミューン インコーポレイテッド | Ｈｌａ−ａ２．１結合ペプチドおよびそれらの用途 |
| EP2187937A1 (de) * | 2007-09-11 | 2010-05-26 | Mondobiotech Laboratories AG | Verwendung des peptids pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys als therapeutisches mittel |
| WO2010086294A2 (en) | 2009-01-28 | 2010-08-05 | Epimmune Inc. | Pan-dr binding polypeptides and uses thereof |
| TWI623618B (zh) | 2011-07-12 | 2018-05-11 | 傳斯堅公司 | Ｈｂｖ聚合酶突變體 |
| GB201223386D0 (en) * | 2012-12-24 | 2013-02-06 | Immune Targeting Systems Its Ltd | Vaccine |
| WO2015187009A1 (en) * | 2014-06-02 | 2015-12-10 | Isa Pharmaceuticals B.V. | Synthetic long peptides (slp) for therapeutic vaccination against hepatitis b virus infection |
| EP3443107A1 (de) | 2016-04-13 | 2019-02-20 | Synthetic Genomics, Inc. | Rekombinante arterivirus-replikon-systeme und verwendungen davon |
| KR20230030032A (ko) | 2016-06-20 | 2023-03-03 | 아이에스에이 파마슈티컬즈 비.브이. | 펩타이드 백신의 제형 |
| BR112019007433A2 (pt) | 2016-10-17 | 2019-07-02 | Synthetic Genomics Inc | sistemas de replicon de vírus recombinante e usos dos mesmos |
| AU2017372731B2 (en) | 2016-12-05 | 2024-05-23 | Janssen Pharmaceuticals, Inc. | Compositions and methods for enhancing gene expression |
| KR20200101416A (ko) * | 2017-12-19 | 2020-08-27 | 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 | B형 간염 바이러스(hbv) 백신 및 그 용도 |
| US11389531B2 (en) | 2017-12-19 | 2022-07-19 | Janssen Sciences Ireland Unlimited Company | Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines |
| EA202091513A1 (ru) | 2017-12-19 | 2020-09-09 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Вакцины против вируса гепатита b (hbv) и их применение |
| EA202091516A1 (ru) | 2017-12-19 | 2020-11-03 | Янссен Сайенсиз Айрлэнд Анлимитед Компани | Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv) |
| EP3740245A4 (de) | 2018-01-19 | 2022-01-05 | Janssen Pharmaceuticals, Inc. | Auslösung und verstärkung von immunreaktionen unter verwendung rekombinanter replikonsysteme |
| KR102234027B1 (ko) * | 2018-05-09 | 2021-03-31 | 서울대학교산학협력단 | B형 간염 바이러스 유래 폴리펩티드 및 이의 항바이러스 용도 |
| WO2023009770A1 (en) * | 2021-07-30 | 2023-02-02 | Tevogen Bio, Inc. | Methods for developing cd3+cd8+ cells against multiple viral epitopes for treatment of viral infections including variants evolving to escape previous immunity |
| CN114478711A (zh) * | 2022-01-05 | 2022-05-13 | 成都朗谷生物科技股份有限公司 | 一种针对乙型肝炎病毒的抗原肽及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ244102A (en) * | 1991-08-26 | 1996-12-20 | Scripps Research Inst | Peptides inducing cytotoxic t lymphocyte responses against hbv antigen and their use |
| EP1704868A1 (de) * | 1992-08-07 | 2006-09-27 | Pharmexa Inc. | HLA Bindepeptide und ihre Verwendungen |
| BR9406652A (pt) * | 1993-03-05 | 1996-09-10 | Cytel Corp | Composição |
-
1994
- 1994-08-01 AT AT94925160T patent/ATE227118T1/de active
- 1994-08-01 NZ NZ271531A patent/NZ271531A/en not_active IP Right Cessation
- 1994-08-01 AU AU75184/94A patent/AU702367B2/en not_active Ceased
- 1994-08-01 JP JP50605395A patent/JP3650110B2/ja not_active Expired - Fee Related
- 1994-08-01 WO PCT/US1994/008685 patent/WO1995003777A1/en active IP Right Grant
- 1994-08-01 PT PT94925160T patent/PT726758E/pt unknown
- 1994-08-01 CA CA002168583A patent/CA2168583C/en not_active Expired - Fee Related
- 1994-08-01 DE DE69431665T patent/DE69431665T2/de not_active Expired - Lifetime
- 1994-08-01 EP EP94925160A patent/EP0726758B1/de not_active Expired - Lifetime
- 1994-08-01 DK DK94925160T patent/DK0726758T3/da active
- 1994-08-01 ES ES94925160T patent/ES2187530T3/es not_active Expired - Lifetime
-
2004
- 2004-09-30 JP JP2004287144A patent/JP2005170926A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0726758B1 (de) | 2002-11-06 |
| DE69431665T2 (de) | 2003-08-21 |
| CA2168583A1 (en) | 1995-02-09 |
| CA2168583C (en) | 2007-10-02 |
| EP0726758A4 (de) | 1997-01-29 |
| WO1995003777A1 (en) | 1995-02-09 |
| JPH09501165A (ja) | 1997-02-04 |
| ES2187530T3 (es) | 2003-06-16 |
| DK0726758T3 (da) | 2003-03-03 |
| AU7518494A (en) | 1995-02-28 |
| NZ271531A (en) | 1998-02-26 |
| ATE227118T1 (de) | 2002-11-15 |
| JP2005170926A (ja) | 2005-06-30 |
| PT726758E (pt) | 2003-03-31 |
| AU702367B2 (en) | 1999-02-18 |
| JP3650110B2 (ja) | 2005-05-18 |
| EP0726758A1 (de) | 1996-08-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |