ATE227118T1 - Peptide zum induzieren einer antwort der zytotoxischen t-lymphozythen gerichetetgegen das hepatitis b-virus - Google Patents

Peptide zum induzieren einer antwort der zytotoxischen t-lymphozythen gerichetetgegen das hepatitis b-virus

Info

Publication number
ATE227118T1
ATE227118T1 AT94925160T AT94925160T ATE227118T1 AT E227118 T1 ATE227118 T1 AT E227118T1 AT 94925160 T AT94925160 T AT 94925160T AT 94925160 T AT94925160 T AT 94925160T AT E227118 T1 ATE227118 T1 AT E227118T1
Authority
AT
Austria
Prior art keywords
peptides
virus
cytotoxic
against hepatitis
induring
Prior art date
Application number
AT94925160T
Other languages
English (en)
Inventor
Francis V Chisari
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE227118T1 publication Critical patent/ATE227118T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT94925160T 1993-08-02 1994-08-01 Peptide zum induzieren einer antwort der zytotoxischen t-lymphozythen gerichetetgegen das hepatitis b-virus ATE227118T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10087093A 1993-08-02 1993-08-02
PCT/US1994/008685 WO1995003777A1 (en) 1993-08-02 1994-08-01 Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus

Publications (1)

Publication Number Publication Date
ATE227118T1 true ATE227118T1 (de) 2002-11-15

Family

ID=22281958

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94925160T ATE227118T1 (de) 1993-08-02 1994-08-01 Peptide zum induzieren einer antwort der zytotoxischen t-lymphozythen gerichetetgegen das hepatitis b-virus

Country Status (11)

Country Link
EP (1) EP0726758B1 (de)
JP (2) JP3650110B2 (de)
AT (1) ATE227118T1 (de)
AU (1) AU702367B2 (de)
CA (1) CA2168583C (de)
DE (1) DE69431665T2 (de)
DK (1) DK0726758T3 (de)
ES (1) ES2187530T3 (de)
NZ (1) NZ271531A (de)
PT (1) PT726758E (de)
WO (1) WO1995003777A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6607727B1 (en) 1991-08-26 2003-08-19 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitus B virus
US7611713B2 (en) 1993-03-05 2009-11-03 Pharmexa Inc. Inducing cellular immune responses to hepatitis B virus using peptide compositions
US6689363B1 (en) 1992-01-29 2004-02-10 Epimmune Inc. Inducing cellular immune responses to hepatitis B virus using peptide and nucleic acid compositions
US6235288B1 (en) 1992-08-26 2001-05-22 The Scripps Research Institute Peptides for inducing cytotoxic T lymphocyte responses to hepatitis B virus
US5858689A (en) * 1993-07-22 1999-01-12 Ludwig Institute For Cancer Research Isolated peptides derived from the gage tumor rejection antigen precursor and uses thereof
EP0914142B9 (de) * 1996-03-11 2012-01-04 Epimmune Inc. Peptide mit erhöhter bindungsaffinität für mindestens drei hla-a3-ähnliche moleküle
DE69820486D1 (de) * 1998-01-19 2004-01-22 Mogam Biotechnology Res Inst Y Liposomen, enthaltend peptidantigene, welche vom x-protein aus hepatitis b virus abstammen
CA2370413A1 (en) * 1999-06-29 2001-01-04 Epimmune Inc. Hla binding peptides and their uses
WO2002020616A1 (en) * 2000-09-01 2002-03-14 Epimmune Inc. Hla-a2.1 binding peptides and their uses
KR20100056507A (ko) * 2007-09-11 2010-05-27 몬도바이오테크 래보래토리즈 아게 치료제로서의 펩티드 pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys의 용도
EP2391635B1 (de) 2009-01-28 2017-04-26 Epimmune Inc. Pan-dr-bindende polypeptide und verwendungen davon
TWI575070B (zh) * 2011-07-12 2017-03-21 傳斯堅公司 Hbv聚合酶突變體
GB201223386D0 (en) * 2012-12-24 2013-02-06 Immune Targeting Systems Its Ltd Vaccine
CA2950863C (en) * 2014-06-02 2023-01-17 Isa Pharmaceuticals B.V. Synthetic long peptides (slp) for therapeutic vaccination against hepatitis b virus infection
EP3443107A1 (de) 2016-04-13 2019-02-20 Synthetic Genomics, Inc. Rekombinante arterivirus-replikon-systeme und verwendungen davon
SG11201811442UA (en) 2016-06-20 2019-01-30 Isa Pharmaceuticals B V Formulation of a peptide vaccine
WO2018075235A1 (en) 2016-10-17 2018-04-26 Synthetic Genomics, Inc. Recombinant virus replicon systems and uses thereof
EP3548625B1 (de) 2016-12-05 2024-06-26 Janssen Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur erhöhung der genexpression
US11389531B2 (en) 2017-12-19 2022-07-19 Janssen Sciences Ireland Unlimited Company Methods and apparatus for the delivery of hepatitis B virus (HBV) vaccines
EA202091516A1 (ru) 2017-12-19 2020-11-03 Янссен Сайенсиз Айрлэнд Анлимитед Компани Способы и композиции для индукции иммунного ответа против вируса гепатита b (hbv)
KR20200101416A (ko) * 2017-12-19 2020-08-27 얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 B형 간염 바이러스(hbv) 백신 및 그 용도
US11021692B2 (en) 2017-12-19 2021-06-01 Janssen Sciences Ireland Unlimited Company Hepatitis B virus (HBV) vaccines and uses thereof
CN111902163B (zh) 2018-01-19 2024-02-13 杨森制药公司 使用重组复制子系统诱导和增强免疫应答
KR102234027B1 (ko) * 2018-05-09 2021-03-31 서울대학교산학협력단 B형 간염 바이러스 유래 폴리펩티드 및 이의 항바이러스 용도
JP2024527098A (ja) * 2021-07-30 2024-07-19 テヴォジェン バイオ インコーポレイテッド 以前の免疫から逃れるように進化する変異体を含むウイルス感染症を治療するための複数のウイルスエピトープに対するcd3+cd8+細胞を開発するための方法
CN118580322A (zh) * 2022-01-05 2024-09-03 成都朗谷生物科技股份有限公司 针对乙型肝炎病毒的抗原肽

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL102963A0 (en) * 1991-08-26 1993-01-31 Scripps Research Inst Peptides for inducing cytotoxic t lymphocyte responses to hepatitis b virus
IL106610A0 (en) * 1992-08-07 1993-12-08 Cytel Corp Hla binding peptides and their uses
NZ263050A (en) * 1993-03-05 1997-11-24 Cytel Corp Compositions of immunogenic peptides with hla-a2.1 binding motifs

Also Published As

Publication number Publication date
DK0726758T3 (da) 2003-03-03
JPH09501165A (ja) 1997-02-04
PT726758E (pt) 2003-03-31
ES2187530T3 (es) 2003-06-16
JP3650110B2 (ja) 2005-05-18
EP0726758B1 (de) 2002-11-06
JP2005170926A (ja) 2005-06-30
WO1995003777A1 (en) 1995-02-09
EP0726758A1 (de) 1996-08-21
AU7518494A (en) 1995-02-28
AU702367B2 (en) 1999-02-18
DE69431665T2 (de) 2003-08-21
DE69431665D1 (de) 2002-12-12
NZ271531A (en) 1998-02-26
CA2168583C (en) 2007-10-02
EP0726758A4 (de) 1997-01-29
CA2168583A1 (en) 1995-02-09

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