DE69431531D1 - Immortalisierte menschliche fötale osteoblastenzellen - Google Patents

Immortalisierte menschliche fötale osteoblastenzellen

Info

Publication number
DE69431531D1
DE69431531D1 DE69431531T DE69431531T DE69431531D1 DE 69431531 D1 DE69431531 D1 DE 69431531D1 DE 69431531 T DE69431531 T DE 69431531T DE 69431531 T DE69431531 T DE 69431531T DE 69431531 D1 DE69431531 D1 DE 69431531D1
Authority
DE
Germany
Prior art keywords
human fetal
east
blast cells
immortalized human
immortalized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69431531T
Other languages
English (en)
Other versions
DE69431531T2 (de
Inventor
Steven A Harris
Thomas C Spelsberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mayo Foundation for Medical Education and Research
Original Assignee
Mayo Foundation for Medical Education and Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/089,848 external-priority patent/US5691175A/en
Application filed by Mayo Foundation for Medical Education and Research filed Critical Mayo Foundation for Medical Education and Research
Publication of DE69431531D1 publication Critical patent/DE69431531D1/de
Application granted granted Critical
Publication of DE69431531T2 publication Critical patent/DE69431531T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0654—Osteocytes, Osteoblasts, Odontocytes; Bones, Teeth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/04—Immortalised cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/22011—Polyomaviridae, e.g. polyoma, SV40, JC
    • C12N2710/22022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
DE69431531T 1993-07-12 1994-07-12 Immortalisierte menschliche fötale osteoblastenzellen Expired - Fee Related DE69431531T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/089,848 US5691175A (en) 1993-07-12 1993-07-12 Immortalized human fetal osteoblastic cells
US08/273,351 US5681701A (en) 1993-07-12 1994-07-11 Immortalized human fetal osteoblastic cells
PCT/US1994/007723 WO1995002687A1 (en) 1993-07-12 1994-07-12 Immortalized human fetal osteoblastic cells

Publications (2)

Publication Number Publication Date
DE69431531D1 true DE69431531D1 (de) 2002-11-14
DE69431531T2 DE69431531T2 (de) 2003-02-27

Family

ID=26780994

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69431531T Expired - Fee Related DE69431531T2 (de) 1993-07-12 1994-07-12 Immortalisierte menschliche fötale osteoblastenzellen

Country Status (7)

Country Link
US (2) US5681701A (de)
EP (1) EP0743982B1 (de)
AT (1) ATE225848T1 (de)
AU (1) AU7327694A (de)
CA (1) CA2166973C (de)
DE (1) DE69431531T2 (de)
WO (1) WO1995002687A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5683906A (en) * 1994-09-09 1997-11-04 Zymogenetics, Inc. Preparation of immortalized cells
EP1441029A1 (de) * 1994-11-08 2004-07-28 CellFactors plc Humane Zelllinien
GB9515327D0 (en) * 1995-07-26 1995-09-20 Univ London Site-directed bone formation
US6713247B1 (en) * 1996-09-03 2004-03-30 Signal Pharmaceuticials, Inc. Human CNS cell lines and methods of use therefor
JP2002502822A (ja) * 1998-02-10 2002-01-29 オレゴン ヘルス サイエンシーズ ユニバーシティー 骨芽細胞の前駆細胞による骨欠損の治療
US6995018B1 (en) * 1999-04-09 2006-02-07 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Complex formed by N-linked glycoproteins (SIBLINGS)and Factor H
AU2005201918B2 (en) * 1999-09-13 2009-01-22 Wyeth Pharmaceutical compositions and methods of using secreted frizzled related protein
MXPA02002624A (es) * 1999-09-13 2002-07-30 Wyeth Corp Composiciones farmaceuticas y metodos de uso de proteinas secretadas relacionadas con la familia "frizzled".
EP1207196A1 (de) * 2000-10-27 2002-05-22 Societe Des Produits Nestle S.A. Immortalisierte pre-osteoblasten und verfahren zur deren herstellung
IL159578A0 (en) * 2001-07-06 2004-06-01 Geron Corp Messenchymal cells and osteoblasts from human embryonic stem cell
CH695985A5 (de) * 2002-01-21 2006-11-15 Straumann Holding Ag Oberflächenmodifizierte Implantate.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03504799A (ja) * 1988-04-12 1991-10-24 マサチューセッツ・インスティチュート・オブ・テクノロジー 真核細胞の細胞型を操作する方法
US5028425A (en) * 1988-07-07 1991-07-02 The United States Of America As Represented By The Department Of Health And Human Services Synthetic vaccine against P. falciparum malaria

Also Published As

Publication number Publication date
EP0743982B1 (de) 2002-10-09
EP0743982A1 (de) 1996-11-27
AU7327694A (en) 1995-02-13
ATE225848T1 (de) 2002-10-15
US5693511A (en) 1997-12-02
WO1995002687A1 (en) 1995-01-26
DE69431531T2 (de) 2003-02-27
CA2166973C (en) 2007-01-30
CA2166973A1 (en) 1995-01-26
US5681701A (en) 1997-10-28

Similar Documents

Publication Publication Date Title
GR1000023B (el) Καρβαμικος φαινυλεστηρ.
IT1237813B (it) Schiuma siliconica e procedimento per la sua produzione.
DE69024135D1 (de) Toner- und Entwicklerzusammensetzungen mit ladungsverbessernden Hilfsmitteln
DE3787732D1 (de) Intraokulare anpassungslinse und linsenreihen.
DE69431531D1 (de) Immortalisierte menschliche fötale osteoblastenzellen
DE3773293D1 (de) Weiche intraokulare linse.
NO931138D0 (no) Omco-foetalt gen, genprodukt og anvendelse derav
DK430189A (da) Fremgangsmaade til fremstilling af et aromatiseringsmiddel og det fremstillede middel
FR2631239B1 (fr) Anticorps monoclonal humain et hybridome le produisant
ITMI910221A1 (it) Anello di tenuta e procedimento per la sua produzione
DE3762780D1 (de) Lichtempfindliches gemisch und daraus hergestelltes lichtempfindliches aufzeichnungsmaterial.
BR9305036A (pt) Sulfonamidas N,N-dissubstituidas, mistura sensivel á radiaçáo e material de registro
NO892269D0 (no) Ikke-hyperglykosylerte hepatitt b-virus-proteiner samt ekspresjons-"kassetter" og fremgangsmaate for fremstilling avproteinene.
BG95677A (bg) Резистентни на хербициди анаs делеционни мутанти
DK27591D0 (da) Klonet nephritis antigen
DE3789593D1 (de) Lichtempfindliches Gemisch und hieraus hergestelltes lichtempfindliches Kopiermaterial.
FI974018A (fi) Ihmisen 2 integriini -alayksikkö
DE59107300D1 (de) Verwendung amphiphiler elastomerer Blockcopolymerisate
FI891596A (fi) Apparat foer kontinuerlig provtagning av lut ur en massakokare.
IT1133899B (it) Rivestimento refrattario per siviere e procedimento per la sua fabbricazione
IT8867157A0 (it) Supporto elastico di tipo perfezionato e procedimento per la sua realizzazione
SU662088A1 (ru) Протез предплечь
KR900009386U (ko) 스피커의 진동판
DE3880277D1 (de) Lichtempfindliches elektrophotographisches material.
DK0484331T3 (da) Enkeltkrystaller af -g(b)-phenylpropiophenoner

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KUDLEK & GRUNERT PATENTANWAELTE PARTNERSCHAFT, 803

8339 Ceased/non-payment of the annual fee