DE69431049D1 - Stickstoff-schwefel-liganden auf imidazolbasis verwendbar in radiographischen abbildungsmitteln - Google Patents
Stickstoff-schwefel-liganden auf imidazolbasis verwendbar in radiographischen abbildungsmittelnInfo
- Publication number
- DE69431049D1 DE69431049D1 DE69431049T DE69431049T DE69431049D1 DE 69431049 D1 DE69431049 D1 DE 69431049D1 DE 69431049 T DE69431049 T DE 69431049T DE 69431049 T DE69431049 T DE 69431049T DE 69431049 D1 DE69431049 D1 DE 69431049D1
- Authority
- DE
- Germany
- Prior art keywords
- imidazole
- radiographic imaging
- imaging media
- ligands used
- based nitrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- PFRUBEOIWWEFOL-UHFFFAOYSA-N [N].[S] Chemical compound [N].[S] PFRUBEOIWWEFOL-UHFFFAOYSA-N 0.000 title 1
- 238000003384 imaging method Methods 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3094093A | 1993-03-12 | 1993-03-12 | |
PCT/US1994/002483 WO1994020148A1 (en) | 1993-03-12 | 1994-03-09 | Imidazole based nitrogen-sulfur ligands useful in radiographic imaging agents |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69431049D1 true DE69431049D1 (de) | 2002-08-29 |
DE69431049T2 DE69431049T2 (de) | 2003-03-13 |
Family
ID=21856803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69431049T Expired - Fee Related DE69431049T2 (de) | 1993-03-12 | 1994-03-09 | Stickstoff-schwefel-liganden auf imidazolbasis verwendbar in radiographischen abbildungsmitteln |
Country Status (6)
Country | Link |
---|---|
US (2) | US5623077A (de) |
EP (1) | EP0689463B1 (de) |
JP (1) | JPH08507528A (de) |
AU (1) | AU6362294A (de) |
DE (1) | DE69431049T2 (de) |
WO (1) | WO1994020148A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0518952A2 (pt) * | 2004-12-17 | 2008-12-16 | Koninkl Philips Electronics Nv | mÉtodo para a produÇço de um agente de contraste marcador ou um agente terapÊutico, agentes de contraste marcadores, e, uso dos agentes de contraste marcadores ou dos agentes terapÊuticos de marcaÇço |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52111572A (en) * | 1976-03-16 | 1977-09-19 | Santen Pharmaceutical Co Ltd | Nn*mercapto substituted acyl**hystidine |
US4193979A (en) * | 1978-05-22 | 1980-03-18 | G. D. Searle & Co. | Sodium 3-[[[2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethyl]-amino]carbonyl]-2-pyridinecarboxylic acid and related compounds labeled with technetium-99m |
JPS5692276A (en) * | 1979-12-26 | 1981-07-25 | Nippon Chemiphar Co Ltd | Dialuminum salt of n-(beta-(n'-acylamino)propionyl) histidine and its preparation |
EP0322876A3 (de) * | 1987-12-29 | 1990-09-05 | Nihon Medi-Physics Co., Ltd. | Chelierende Verbindungen und deren Verwendung |
ES2009921A6 (es) * | 1988-05-26 | 1989-10-16 | Vinas Lab | Procedimiento para la obtencion de derivados imidazolicos. |
US5011925A (en) * | 1989-03-09 | 1991-04-30 | Mallinckrodt, Inc. | Morpholinoamido EDTA derivatives |
US5376356A (en) * | 1989-03-14 | 1994-12-27 | Neorx Corporation | Imaging tissue sites of inflammation |
FR2655339B2 (fr) * | 1989-04-19 | 1992-04-10 | Medgenix Group Sa | Composes et complexes utiles notamment en imagerie medicale. |
DE3930674A1 (de) * | 1989-09-11 | 1991-03-21 | Diagnostikforschung Inst | Bifunktionelle chelatbildner zur komplexierung von tc- und re-isotopen, verfahren zu ihrer herstellung und darstellung von konjugaten daraus sowie deren verwendung in diagnostik und therapie |
US5382654A (en) * | 1992-02-05 | 1995-01-17 | Mallinckrodt Medical, Inc. | Radiolabelled peptide compounds |
US5217706A (en) * | 1990-11-21 | 1993-06-08 | Mallinckrodt Medical, Inc. | Complexes and compositions for magnetic resonance imaging |
US5330737A (en) * | 1991-12-06 | 1994-07-19 | Mallinckrodt Medical, Inc. | Nitrogen-sulfur ligands as opiate receptor drug mimics |
US5371184A (en) * | 1992-02-05 | 1994-12-06 | Mallinckrodt Medical, Inc. | Radiolabelled peptide compounds |
-
1994
- 1994-03-09 EP EP94910883A patent/EP0689463B1/de not_active Expired - Lifetime
- 1994-03-09 JP JP6520260A patent/JPH08507528A/ja not_active Ceased
- 1994-03-09 WO PCT/US1994/002483 patent/WO1994020148A1/en active IP Right Grant
- 1994-03-09 AU AU63622/94A patent/AU6362294A/en not_active Abandoned
- 1994-03-09 DE DE69431049T patent/DE69431049T2/de not_active Expired - Fee Related
-
1995
- 1995-04-10 US US08/420,612 patent/US5623077A/en not_active Expired - Fee Related
- 1995-04-10 US US08/419,319 patent/US5653958A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5623077A (en) | 1997-04-22 |
AU6362294A (en) | 1994-09-26 |
EP0689463A1 (de) | 1996-01-03 |
EP0689463B1 (de) | 2002-07-24 |
DE69431049T2 (de) | 2003-03-13 |
WO1994020148A1 (en) | 1994-09-15 |
US5653958A (en) | 1997-08-05 |
JPH08507528A (ja) | 1996-08-13 |
EP0689463A4 (de) | 1996-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |