DE69430626T2 - Neue phospholipid-saccharid-konjugate - Google Patents
Neue phospholipid-saccharid-konjugateInfo
- Publication number
- DE69430626T2 DE69430626T2 DE69430626T DE69430626T DE69430626T2 DE 69430626 T2 DE69430626 T2 DE 69430626T2 DE 69430626 T DE69430626 T DE 69430626T DE 69430626 T DE69430626 T DE 69430626T DE 69430626 T2 DE69430626 T2 DE 69430626T2
- Authority
- DE
- Germany
- Prior art keywords
- conjugates
- saccharid
- phospholipid
- new phospholipid
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/030,793 US5354853A (en) | 1993-03-12 | 1993-03-12 | Phospholipid-saccharide conjugates |
PCT/US1994/002535 WO1994021656A2 (en) | 1993-03-12 | 1994-03-09 | Novel phospholipid-saccharide conjugates |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69430626D1 DE69430626D1 (de) | 2002-06-20 |
DE69430626T2 true DE69430626T2 (de) | 2002-12-19 |
Family
ID=21856073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69430626T Expired - Fee Related DE69430626T2 (de) | 1993-03-12 | 1994-03-09 | Neue phospholipid-saccharid-konjugate |
Country Status (7)
Country | Link |
---|---|
US (1) | US5354853A (de) |
EP (1) | EP0688329B1 (de) |
JP (1) | JPH08507544A (de) |
AT (1) | ATE217631T1 (de) |
CA (1) | CA2158055A1 (de) |
DE (1) | DE69430626T2 (de) |
WO (1) | WO1994021656A2 (de) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10207177A1 (de) * | 2002-02-19 | 2003-09-04 | Novosom Ag | Fakultativ kationische Lipide |
DE102004038443A1 (de) * | 2004-08-07 | 2006-03-16 | Bioghurt Biogarde Gmbh & Co. Kg | Verfahren zur enzymatischen Herstellung und/oder Modifikation von Phospholipiden |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11511128A (ja) * | 1995-08-01 | 1999-09-28 | ノバルティス・アクチエンゲゼルシャフト | リポソームオリゴヌクレオチド組成物 |
AU5571196A (en) * | 1996-04-24 | 1997-11-12 | Sdg, Inc. | Improved masking of liposomes from res recognition |
PT939647E (pt) * | 1996-08-27 | 2002-04-29 | Chiron Corp | Glicpconjugados do serogrupo b de neisseria meningitidis e metodos de utilizacao dos mesmos |
US6071532A (en) * | 1996-10-15 | 2000-06-06 | Emory University | Synthesis of glycophospholipid and peptide-phospholipid conjugates and uses thereof |
US6096291A (en) * | 1996-12-27 | 2000-08-01 | Biovector Therapeutics, S.A. | Mucosal administration of substances to mammals |
US6204254B1 (en) | 1997-09-12 | 2001-03-20 | Baxter International, Inc. | Biocompatible surfaces and a method for their preparation |
US6797289B2 (en) | 1998-02-13 | 2004-09-28 | Nutramax Laboratories, Inc. | Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals |
US6451771B1 (en) | 1999-02-12 | 2002-09-17 | Nutramax Laboratories, Inc. | Use of anabolic agents anti-catabolic agents and antioxidant agents for protection treatment and repair of connective tissues in humans and animals |
US20070141181A1 (en) | 1998-02-13 | 2007-06-21 | Nutramax Laboratories, Inc. | Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals |
JP3861133B2 (ja) * | 1999-12-07 | 2006-12-20 | 独立行政法人産業技術総合研究所 | グルコシルフォスファチジルグリセロール誘導体の製造方法 |
US8501701B2 (en) * | 2000-01-10 | 2013-08-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Use of lipid conjugates in the treatment of disease |
US8076312B2 (en) * | 2000-01-10 | 2011-12-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd | Use of lipid conjugates in the treatment of disease |
US7893226B2 (en) | 2004-09-29 | 2011-02-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Use of lipid conjugates in the treatment of diseases |
US20090325876A1 (en) * | 2004-09-29 | 2009-12-31 | Saul Yedgar | Use of lipid conjugates in the treatment of diseases associated with vasculature |
US7608598B2 (en) | 2000-01-10 | 2009-10-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of conjunctivitis |
US20060189570A1 (en) * | 2000-01-10 | 2006-08-24 | Saul Yedgar | Use of lipid conjugates in the treatment of infection |
US9040078B2 (en) | 2000-01-10 | 2015-05-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of diseases of the nervous system |
US8304395B2 (en) * | 2000-01-10 | 2012-11-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Lipid conjugates in the treatment of disease |
US7772196B2 (en) * | 2000-01-10 | 2010-08-10 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of diseases |
US8916539B2 (en) * | 2000-01-10 | 2014-12-23 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of disease |
US7811999B2 (en) | 2000-01-10 | 2010-10-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | Use of lipid conjugates in the treatment of diseases |
US7393938B2 (en) * | 2000-01-10 | 2008-07-01 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of diseases |
US6749865B2 (en) * | 2000-02-15 | 2004-06-15 | Genzyme Corporation | Modification of biopolymers for improved drug delivery |
AU2001238346A1 (en) | 2000-02-15 | 2001-08-27 | Genzyme Corporation | Modification of biopolymers for improved drug delivery |
DE50115872D1 (de) * | 2000-12-06 | 2011-06-16 | Ecole Polytech | Verfahren zur herstellung eines bioanalytischen reagenzes, nachweisverfahren beruhend auf der verwendung des bioanalytischen reagenz, sowie dessen verwendung |
US8883761B2 (en) * | 2001-01-10 | 2014-11-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of lipid conjugates in the treatment of diseases associated with vasculature |
US20050013810A1 (en) * | 2001-05-08 | 2005-01-20 | Waller Edmund K | Regulating immune response using dendritic cells |
US20060193906A1 (en) * | 2002-01-30 | 2006-08-31 | National Institute Of Advanced Industrial Science And Technology | Sugar-modified liposome and products comprising the liposome |
US7070801B2 (en) * | 2002-01-30 | 2006-07-04 | National Institute Of Advanced Industrial Science And Technology | Sugar-modified liposome and products comprising the liposome |
US7299805B2 (en) * | 2002-06-07 | 2007-11-27 | Marctec, Llc | Scaffold and method for implanting cells |
US20040131631A1 (en) * | 2002-11-22 | 2004-07-08 | Alexander Andrianov | Polyphosphazene immunostimulants |
ATE389731T1 (de) * | 2002-12-12 | 2008-04-15 | Novozymes As | Verfahren zur auswahl eines lipolytischen enzyms |
WO2005011632A1 (ja) * | 2003-08-01 | 2005-02-10 | National Institute Of Advanced Industrial Science And Technology | 糖鎖を有する標的指向性および腸管吸収制御性リポソームならびにそれを含む癌治療薬および診断薬 |
WO2005049631A1 (en) * | 2003-11-18 | 2005-06-02 | The Malaghan Institute Of Medical Research | Synthetic molecules having immune activity |
WO2005090370A1 (en) | 2004-02-05 | 2005-09-29 | The Regents Of The University Of California | Pharmacologically active agents containing esterified phosphonates and methods for use thereof |
CN104546891A (zh) * | 2005-08-03 | 2015-04-29 | 塞尔索斯治疗公司 | 脂质结合物在囊性纤维化病中的用途及其应用 |
JP4744973B2 (ja) * | 2005-08-05 | 2011-08-10 | 株式会社トプコン | 眼底カメラ |
US8859524B2 (en) | 2005-11-17 | 2014-10-14 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Lipid conjugates in the treatment of chronic rhinosinusitis |
US20110130555A1 (en) | 2009-05-11 | 2011-06-02 | Saul Yedgar | Lipid-polymer conjugates, their preparation and uses thereof |
US8906882B2 (en) | 2005-11-17 | 2014-12-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Lipid conjugates in the treatment of allergic rhinitis |
US20080183282A1 (en) * | 2006-03-09 | 2008-07-31 | Saul Yedgar | Use of lipid conjugates for the coating of stents and catheters |
CA2705785A1 (en) * | 2006-11-14 | 2008-05-22 | Saul Yedgar | Use of lipid conjugates in the treatment of diseases or disorders of the eye |
KR100829595B1 (ko) | 2006-12-11 | 2008-05-14 | 한국화학연구원 | 당이 결합된 인지질로 수식된 리포솜 및 이의 제조방법 |
WO2013035757A1 (ja) * | 2011-09-07 | 2013-03-14 | 国立大学法人京都大学 | 6炭糖-6-リン酸修飾コレステロール誘導体含有製剤 |
EP3059236A1 (de) * | 2015-02-23 | 2016-08-24 | Abivax | Neue Chinolinderivate zur Verwendung bei der Behandlung und Prävention von Virusinfektionen |
EP3058940A1 (de) * | 2015-02-23 | 2016-08-24 | Abivax | Chinolin-Derivate zur Behandlung oder Vorbeugung von viralen Infektionen |
CN105153251B (zh) * | 2015-09-29 | 2018-03-20 | 浙江合糖科技有限公司 | 一种单糖甲苷的苄基化方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4585762A (en) * | 1982-07-30 | 1986-04-29 | Fujisawa Pharmaceutical Co., Ltd. | Phospholipid derivatives, processes for use thereof and pharmaceutical composition of the same |
JPS59187792A (ja) * | 1983-04-11 | 1984-10-24 | Meito Sangyo Kk | 酵素法リン脂質糖類誘導体の製法 |
US4873322A (en) * | 1986-01-24 | 1989-10-10 | Ciba-Geigy Corporation | Saccharide derivatives and processes for their manufacture |
FR2596651B1 (fr) * | 1986-04-08 | 1989-11-10 | Centre Nat Rech Scient | Nouveaux liposomes a base de phosphatidylinositolmannosides, et compositions pharmaceutiques les contenant |
WO1989008499A1 (en) * | 1988-03-17 | 1989-09-21 | Nippon Fine Chemical Co., Ltd. | Liposome |
GB8825290D0 (en) * | 1988-10-28 | 1988-11-30 | Hounsell E F | Characterisation of glycoproteins |
-
1993
- 1993-03-12 US US08/030,793 patent/US5354853A/en not_active Expired - Fee Related
-
1994
- 1994-03-09 JP JP6521094A patent/JPH08507544A/ja not_active Ceased
- 1994-03-09 CA CA002158055A patent/CA2158055A1/en not_active Abandoned
- 1994-03-09 EP EP94912202A patent/EP0688329B1/de not_active Expired - Lifetime
- 1994-03-09 AT AT94912202T patent/ATE217631T1/de not_active IP Right Cessation
- 1994-03-09 WO PCT/US1994/002535 patent/WO1994021656A2/en active IP Right Grant
- 1994-03-09 DE DE69430626T patent/DE69430626T2/de not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10207177A1 (de) * | 2002-02-19 | 2003-09-04 | Novosom Ag | Fakultativ kationische Lipide |
DE102004038443A1 (de) * | 2004-08-07 | 2006-03-16 | Bioghurt Biogarde Gmbh & Co. Kg | Verfahren zur enzymatischen Herstellung und/oder Modifikation von Phospholipiden |
Also Published As
Publication number | Publication date |
---|---|
US5354853A (en) | 1994-10-11 |
CA2158055A1 (en) | 1994-09-29 |
EP0688329A1 (de) | 1995-12-27 |
WO1994021656A2 (en) | 1994-09-29 |
JPH08507544A (ja) | 1996-08-13 |
EP0688329B1 (de) | 2002-05-15 |
WO1994021656A3 (en) | 1994-11-10 |
DE69430626D1 (de) | 2002-06-20 |
ATE217631T1 (de) | 2002-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |