DE69430521D1 - Anwendung von Prostagrandin-Analogen für die Behandlung von Glaukome und okuläre Hypertension - Google Patents
Anwendung von Prostagrandin-Analogen für die Behandlung von Glaukome und okuläre HypertensionInfo
- Publication number
- DE69430521D1 DE69430521D1 DE69430521T DE69430521T DE69430521D1 DE 69430521 D1 DE69430521 D1 DE 69430521D1 DE 69430521 T DE69430521 T DE 69430521T DE 69430521 T DE69430521 T DE 69430521T DE 69430521 D1 DE69430521 D1 DE 69430521D1
- Authority
- DE
- Germany
- Prior art keywords
- glaucoma
- treatment
- analogues
- prostagrandin
- ocular hypertension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 206010018307 Glaucoma and ocular hypertension Diseases 0.000 title abstract 2
- 229940006138 antiglaucoma drug and miotics prostaglandin analogues Drugs 0.000 abstract 2
- 230000004410 intraocular pressure Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16774793A | 1993-12-15 | 1993-12-15 | |
US08/167,470 US5721273A (en) | 1993-12-15 | 1993-12-15 | Use of certain 9-halo-13,14-dihydroprostaglandins to treat glaucoma and ocular hypertension |
US31667294A | 1994-09-30 | 1994-09-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69430521D1 true DE69430521D1 (de) | 2002-06-06 |
Family
ID=27389393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69430521T Expired - Lifetime DE69430521D1 (de) | 1993-12-15 | 1994-12-10 | Anwendung von Prostagrandin-Analogen für die Behandlung von Glaukome und okuläre Hypertension |
Country Status (4)
Country | Link |
---|---|
EP (2) | EP1088816A2 (de) |
AT (1) | ATE216889T1 (de) |
AU (1) | AU687906B2 (de) |
DE (1) | DE69430521D1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6011062A (en) * | 1994-12-22 | 2000-01-04 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
US5631287A (en) * | 1994-12-22 | 1997-05-20 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
US6169111B1 (en) | 1995-06-07 | 2001-01-02 | Alcon Laboratories, Inc. | Conformationally rigid aryl prostaglandins for use in glaucoma therapy |
DE69633136T2 (de) | 1995-12-22 | 2005-09-01 | Alcon Laboratories, Inc., Fort Worth | Substituierte tetrahydrofuran-analoge von prostaglandinen als augendrucksenkende mittel |
US5866602A (en) * | 1995-12-22 | 1999-02-02 | Alcon Laboratories, Inc. | Keto-substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives |
US5814660A (en) * | 1995-12-22 | 1998-09-29 | Alcon Laboratories, Inc. | 9-oxa prostaglandin analogs as ocular hypotensives |
CA2270349A1 (en) * | 1996-11-01 | 1998-05-14 | Jesse A. May | Use of a combination of carbonic anhydrase inhibitors and prostaglandins for treating glaucoma |
WO1998020880A2 (en) * | 1996-11-12 | 1998-05-22 | Alcon Laboratories, Inc. | 11-halo prostaglandins for the treatment of glaucoma or ocular hypertension |
US6458836B1 (en) | 2000-03-16 | 2002-10-01 | Sucampo, A.G. | Treatment of ocular hypertension and glaucoma |
HUP0300391A3 (en) * | 2000-03-16 | 2008-05-28 | Sucampo Ag | Use of prostaglandin related compounds for preparation of composition for use in treatment of ocular hypertension and glaucoma |
MXPA04001604A (es) * | 2001-08-23 | 2004-07-08 | Sucampo Ag | Metodo y composicion para tratamiento de hipertension ocular y glaucoma. |
JP2005519978A (ja) * | 2002-03-28 | 2005-07-07 | スキャンポ・アーゲー | 高眼圧症および緑内障の処置方法 |
KR20180058758A (ko) | 2015-09-22 | 2018-06-01 | 그레이버그 비젼, 인크. | 안구 장애의 치료를 위한 화합물 및 조성물 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3504044A1 (de) * | 1985-02-04 | 1986-08-07 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 9-halogenprostaglandin-clathrate und ihre verwendung als arzneimittel |
DE3510978A1 (de) * | 1985-03-22 | 1986-09-25 | Schering AG, Berlin und Bergkamen, 1000 Berlin | Neue 9-halogenprostaglandine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
IL87116A (en) * | 1987-07-17 | 1993-03-15 | Schering Ag | 9-halogen-(z)-prostaglandin derivatives and pharmaceutical compositions containing the same |
DE4024347A1 (de) * | 1990-07-27 | 1992-01-30 | Schering Ag | Cyclopentanderivate, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung |
DE4036140A1 (de) * | 1990-11-09 | 1992-05-14 | Schering Ag | 9-halogen-11ss-hydroxy-prostaglandinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
DK0656889T3 (da) * | 1992-08-31 | 1999-03-22 | Schering Ag | 9-chlorprostaglandinestere og -amider og deres anvendelse ved fremstilling af lægemidler |
DE4229053A1 (de) * | 1992-08-31 | 1994-03-03 | Schering Ag | Verwendung von Estern und Amiden von 9-Chlor-Prostaglandinen für die Herstellung von Arzneimitteln zur Förderung der Hautdurchblutung |
-
1994
- 1994-11-30 AU AU79138/94A patent/AU687906B2/en not_active Ceased
- 1994-12-10 EP EP00204408A patent/EP1088816A2/de not_active Withdrawn
- 1994-12-10 AT AT94119571T patent/ATE216889T1/de not_active IP Right Cessation
- 1994-12-10 EP EP94119571A patent/EP0667160B1/de not_active Expired - Lifetime
- 1994-12-10 DE DE69430521T patent/DE69430521D1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0667160A2 (de) | 1995-08-16 |
EP0667160B1 (de) | 2002-05-02 |
AU7913894A (en) | 1995-06-22 |
AU687906B2 (en) | 1998-03-05 |
EP1088816A2 (de) | 2001-04-04 |
EP0667160A3 (de) | 1995-11-15 |
ATE216889T1 (de) | 2002-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |