DE69429048T2 - Biologisch erodierbare Vorrichtung zur Verabreichung von Wirkstoffen - Google Patents

Biologisch erodierbare Vorrichtung zur Verabreichung von Wirkstoffen

Info

Publication number
DE69429048T2
DE69429048T2 DE69429048T DE69429048T DE69429048T2 DE 69429048 T2 DE69429048 T2 DE 69429048T2 DE 69429048 T DE69429048 T DE 69429048T DE 69429048 T DE69429048 T DE 69429048T DE 69429048 T2 DE69429048 T2 DE 69429048T2
Authority
DE
Germany
Prior art keywords
administration
hours
active substances
erodible device
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69429048T
Other languages
English (en)
Other versions
DE69429048D1 (de
Inventor
Peter Britton
William P Hart
Patricia Flanagan
Deborah Linkin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Johnson and Johnson Consumer Inc
Original Assignee
McNeil PPC Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeil PPC Inc filed Critical McNeil PPC Inc
Publication of DE69429048D1 publication Critical patent/DE69429048D1/de
Application granted granted Critical
Publication of DE69429048T2 publication Critical patent/DE69429048T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • A61K9/122Foams; Dry foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S261/00Gas and liquid contact apparatus
    • Y10S261/26Foam

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69429048T 1993-08-16 1994-04-13 Biologisch erodierbare Vorrichtung zur Verabreichung von Wirkstoffen Expired - Lifetime DE69429048T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/104,785 US5458884A (en) 1992-09-10 1993-08-16 Bioerodible device for administering active ingredients

Publications (2)

Publication Number Publication Date
DE69429048D1 DE69429048D1 (de) 2001-12-20
DE69429048T2 true DE69429048T2 (de) 2002-07-11

Family

ID=22302367

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69429048T Expired - Lifetime DE69429048T2 (de) 1993-08-16 1994-04-13 Biologisch erodierbare Vorrichtung zur Verabreichung von Wirkstoffen

Country Status (8)

Country Link
US (1) US5458884A (de)
EP (1) EP0643963B1 (de)
KR (1) KR100277483B1 (de)
AT (1) ATE208612T1 (de)
DE (1) DE69429048T2 (de)
DK (1) DK0643963T3 (de)
ES (1) ES2171165T3 (de)
PT (1) PT643963E (de)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
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CA2105887C (en) * 1992-09-10 2004-03-16 Peter Britton Bioerodible device for administering active ingredients
US6479457B2 (en) 1995-06-06 2002-11-12 Kinerton Limited Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
US5656283A (en) * 1995-06-08 1997-08-12 Ortho Pharmaceutical Corporation In-situ lyophilization of vaginal suppository in unit dose applicator and resultant product
US6416779B1 (en) * 1997-06-11 2002-07-09 Umd, Inc. Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections
US6624200B2 (en) 1998-08-25 2003-09-23 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US6248358B1 (en) 1998-08-25 2001-06-19 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets and methods of making and using the same
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
EP1123696B1 (de) * 1998-09-25 2006-05-24 Kao Corporation Zubereitungen für die mundhöhle
US6284262B1 (en) * 1999-01-26 2001-09-04 Virgil A. Place Compact dosage unit for buccal administration of a pharmacologically active agent
US6090401A (en) * 1999-03-31 2000-07-18 Mcneil-Ppc, Inc. Stable foam composition
SE514342C2 (sv) * 1999-05-31 2001-02-12 Nobel Biocare Ab Metod, anordning och användning vid implantat för att tillförsäkra tillförsel av bioaktiv substans till implantatets omgivande ben och/eller vävnad
US20020076440A1 (en) * 1999-06-25 2002-06-20 Thomas Leon Veterinary delivery systems and methods of delivering effective agents to animals
GB2355008A (en) * 1999-10-05 2001-04-11 Procter & Gamble Foam matrix coating material
US6943200B1 (en) 1999-10-05 2005-09-13 Procter & Gamble Company Water unstable foam compositions
AU7752400A (en) * 1999-10-05 2001-05-10 Procter & Gamble Company, The Water unstable foam
WO2001025323A1 (en) * 1999-10-05 2001-04-12 The Procter & Gamble Company Elastic articles and uses thereof
GB2355014A (en) * 1999-10-05 2001-04-11 Procter & Gamble Foams and compositions containing these foams
US6555125B2 (en) 1999-11-30 2003-04-29 Phillip Campbell Lesion and ulcer medication
US6352711B1 (en) * 1999-11-30 2002-03-05 Phillip Campbell Lesion and ulcer medication
JP2004504887A (ja) * 2000-08-02 2004-02-19 アエスクラップ アーゲー ウント コー カーゲー 医療技術製品、その製造方法、およびその外科用用途
US7198801B2 (en) 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
US8980290B2 (en) 2000-08-03 2015-03-17 Antares Pharma Ipl Ag Transdermal compositions for anticholinergic agents
GB2366797A (en) * 2000-09-13 2002-03-20 Procter & Gamble Process for making foam component by pressurising/depressurising
US6756051B1 (en) * 2000-11-15 2004-06-29 Li-Lan H. Chen Bioadhesive, closed-cell foam film, sustained release, delivery devices and methods of making and using same
US8741335B2 (en) 2002-06-14 2014-06-03 Hemcon Medical Technologies, Inc. Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as Chitosan
US7897832B2 (en) * 2001-06-14 2011-03-01 Hemcon Medical Technologies, Inc. Compositions, assemblies, and methods applied during or after a dental procedure to ameliorate fluid loss and/or promote healing, using a hydrophilic polymer sponge structure such as chitosan
AU2002312493B2 (en) 2001-06-14 2007-08-09 Gregory, Kenton W Wound dressing and method for controlling severe, life-threatening bleeding
US7371403B2 (en) 2002-06-14 2008-05-13 Providence Health System-Oregon Wound dressing and method for controlling severe, life-threatening bleeding
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US20050137512A1 (en) 2003-12-23 2005-06-23 Campbell Todd D. Wound dressing and method for controlling severe, life-threatening bleeding
US8269058B2 (en) 2002-06-14 2012-09-18 Hemcon Medical Technologies, Inc. Absorbable tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan
BR0315194A (pt) * 2002-10-31 2005-08-23 Umd Inc Composições terapêuticas para liberação de droga para a, e através da, cobertura epitelial
US20040151756A1 (en) * 2003-02-04 2004-08-05 Richards Anthony P. Edible low density high surface area drug vehicle, method of manufacturing low density high surface area drug vehicle
PT1670433E (pt) 2003-10-10 2012-02-08 Ferring Bv Fórmula farmacológica transdérmica para a minimização de resíduos na pele
US9204957B2 (en) 2005-03-17 2015-12-08 Hemcon Medical Technologies, Inc. Systems and methods for hemorrhage control and or tissue repair
WO2006125642A1 (en) 2005-05-27 2006-11-30 Antares Pharma Ipl Ag Methods and apparatus for transdermal or transmucosal application of testosterone
CA2646667C (en) 2006-04-21 2014-03-11 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
EP2026850B1 (de) 2006-05-23 2014-07-09 Providence Health System-Oregon d/b/a Providence St. Vincent Medical Center Systeme und verfahren zur einführung und anbringung einer verbandstruktur in einem körperlumen oder hohlen körperorgan
WO2009134447A1 (en) 2008-05-02 2009-11-05 Providence Health System-Oregon D/B/A Providence St. Vincent Medical Center Wound dressing devices and methods
WO2010042540A1 (en) 2008-10-06 2010-04-15 Providence Health System - Oregon Foam medical devices and methods
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
BR112018072539A2 (pt) 2016-05-05 2019-03-26 Aquestive Therapeutics, Inc. composições de epinefrina de administração aumentada
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
DE102017112527B4 (de) * 2017-06-07 2019-01-03 Lts Lohmann Therapie-Systeme Ag Schnell zerfallende Schaumwafer mit hohem Flächengewicht
EP4122980A4 (de) * 2020-03-17 2024-03-27 Japan Tobacco Inc Verfahren zur herstellung eines porösen körpers und poröser körper

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292972A (en) * 1980-07-09 1981-10-06 E. R. Squibb & Sons, Inc. Lyophilized hydrocolloio foam
US4642903A (en) * 1985-03-26 1987-02-17 R. P. Scherer Corporation Freeze-dried foam dosage form
FR2634376B1 (fr) * 1988-07-21 1992-04-17 Farmalyoc Nouvelle forme unitaire, solide et poreuse comprenant des microparticules et/ou des nanoparticules, ainsi que sa preparation
US4948580A (en) * 1988-12-08 1990-08-14 E. R. Squibb & Sons, Inc. Muco-bioadhesive composition
US5039540A (en) * 1989-08-14 1991-08-13 Neophore Technologies, Inc. Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs
DE4119140C2 (de) * 1991-06-11 1994-05-11 Merz & Co Gmbh & Co Poröser, in Körperflüssigkeiten und Sekreten löslicher, spongoider Formkörper, dessen Herstellung und Verwendung
US5354558A (en) * 1992-09-10 1994-10-11 Mcneil-Pcc, Inc. Bioerodible contraceptive suppository

Also Published As

Publication number Publication date
DE69429048D1 (de) 2001-12-20
EP0643963A3 (de) 1996-09-11
ES2171165T3 (es) 2002-09-01
EP0643963B1 (de) 2001-11-14
ATE208612T1 (de) 2001-11-15
KR940006574A (ko) 1994-04-25
DK0643963T3 (da) 2002-03-11
KR100277483B1 (ko) 2001-09-17
US5458884A (en) 1995-10-17
PT643963E (pt) 2002-05-31
EP0643963A2 (de) 1995-03-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN