IL107108A0 - Microcapsules,processes for the preparation thereof and contrast compositions containing the same - Google Patents

Microcapsules,processes for the preparation thereof and contrast compositions containing the same

Info

Publication number
IL107108A0
IL107108A0 IL107108A IL10710893A IL107108A0 IL 107108 A0 IL107108 A0 IL 107108A0 IL 107108 A IL107108 A IL 107108A IL 10710893 A IL10710893 A IL 10710893A IL 107108 A0 IL107108 A0 IL 107108A0
Authority
IL
Israel
Prior art keywords
microcapsules
processes
preparation
same
compositions containing
Prior art date
Application number
IL107108A
Other versions
IL107108A (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL107108A0 publication Critical patent/IL107108A0/en
Publication of IL107108A publication Critical patent/IL107108A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

The invention concerns microparticle preparations made from biodegradable copolymers for therapeutic and diagnostic use, in particular for ultrasonic examinations, plus a method of producing such preparations.
IL107108A 1992-09-26 1993-09-26 Microparticle formulation containing biodegradable mixed polymers IL107108A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4232755A DE4232755A1 (en) 1992-09-26 1992-09-26 Microparticle preparations made from biodegradable copolymers

Publications (2)

Publication Number Publication Date
IL107108A0 true IL107108A0 (en) 1993-12-28
IL107108A IL107108A (en) 1998-01-04

Family

ID=6469216

Family Applications (1)

Application Number Title Priority Date Filing Date
IL107108A IL107108A (en) 1992-09-26 1993-09-26 Microparticle formulation containing biodegradable mixed polymers

Country Status (18)

Country Link
EP (1) EP0662005B1 (en)
JP (1) JPH08504398A (en)
KR (1) KR100287975B1 (en)
CN (1) CN1078815C (en)
AT (1) ATE165517T1 (en)
AU (1) AU687360B2 (en)
CA (1) CA2145505C (en)
DE (2) DE4232755A1 (en)
DK (1) DK0662005T3 (en)
ES (1) ES2118251T3 (en)
FI (1) FI117124B (en)
HU (1) HU221972B1 (en)
IL (1) IL107108A (en)
NO (1) NO307692B1 (en)
NZ (1) NZ255409A (en)
TW (1) TW394688B (en)
WO (1) WO1994007539A1 (en)
ZA (1) ZA937099B (en)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US6333021B1 (en) * 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
EP0727225A3 (en) * 1995-02-14 1997-01-15 Sonus Pharma Inc Compositions and methods for directed ultrasound imaging
DE19510690A1 (en) 1995-03-14 1996-09-19 Schering Ag Polymeric nano- and / or microparticles, processes for their production, and use in medical diagnostics and therapy
DE69632401T2 (en) * 1995-06-07 2005-05-19 Imarx Pharmaceutical Corp., Tucson NEW TARGETED MEANS FOR DIAGNOSTIC AND THERAPEUTIC USE
US6821506B2 (en) 1995-06-08 2004-11-23 Barnes-Jewish Hospital Site specific binding system, imaging compositions and methods
US5780010A (en) * 1995-06-08 1998-07-14 Barnes-Jewish Hospital Method of MRI using avidin-biotin conjugated emulsions as a site specific binding system
US6548046B1 (en) 1995-06-08 2003-04-15 Barnes-Jewish Hospital Site specific binding system, imaging compositions and methods
WO1997022409A1 (en) * 1995-12-21 1997-06-26 Drexel University Hollow polymer microcapsules and method of producing
US5849727A (en) * 1996-06-28 1998-12-15 Board Of Regents Of The University Of Nebraska Compositions and methods for altering the biodistribution of biological agents
US6331289B1 (en) 1996-10-28 2001-12-18 Nycomed Imaging As Targeted diagnostic/therapeutic agents having more than one different vectors
WO1998018498A2 (en) * 1996-10-28 1998-05-07 Marsden, John, Christopher Improvements in or relating to diagnostic/therapeutic agents
US6261537B1 (en) 1996-10-28 2001-07-17 Nycomed Imaging As Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors
US6264917B1 (en) 1996-10-28 2001-07-24 Nycomed Imaging As Targeted ultrasound contrast agents
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE19925311B4 (en) 1999-05-27 2004-06-09 Schering Ag Multi-stage process for the production of gas-filled microcapsules
US7220401B2 (en) 1999-09-24 2007-05-22 Barnes-Jewish Hospital Blood clot-targeted nanoparticles
DE10013850A1 (en) * 2000-03-15 2001-09-20 Schering Ag Gas-filled microcapsules, useful for ultrasonic diagnosis, are prepared from functionalized poly(alkyl cyanoacrylate), allowing attachment of e.g. specific-binding agents
DE10119522A1 (en) * 2001-04-20 2002-12-05 Innovacell Biotechnologie Gmbh Preparation and application of a suspension composition with an ultrasound contrast medium
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US7901770B2 (en) 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
CA2585675A1 (en) 2004-11-03 2006-12-28 Iris Molecular Diagnostics, Inc. Microbubbles for affinity separation
JP5188808B2 (en) 2004-11-03 2013-04-24 アイリス モレキュラー ダイアグノスティクス, インコーポレイテッド Homogeneous analyte detection
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7727555B2 (en) 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
KR100845010B1 (en) * 2007-08-29 2008-07-08 한국생명공학연구원 Polymer particles for nir/mr bimodal molecular imaging and method for preparing thereof
CN101518780B (en) * 2008-12-31 2011-09-14 广东省生态环境与土壤研究所 Complexing agent microcapsule for plant soil restoration and preparation method thereof
EP2474327A1 (en) * 2011-01-07 2012-07-11 RWTH Aachen Microdosing of ultrasound contrast agents
CA3196421A1 (en) * 2020-11-20 2022-05-27 Encapsys, Llc Biodegradable, controlled release microcapsules

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0586875A1 (en) * 1988-02-05 1994-03-16 Schering Aktiengesellschaft Ultrasonic contrast agents, process for producing them and their use as diagnostic and therapeutic agents
DE4004430A1 (en) * 1990-02-09 1991-08-14 Schering Ag CONSTRUCTED POLYALDEHYDE CONSTITUENTS
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
GB9106686D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents

Also Published As

Publication number Publication date
HUT71683A (en) 1996-01-29
KR950703367A (en) 1995-09-20
DE59308479D1 (en) 1998-06-04
FI117124B (en) 2006-06-30
NZ255409A (en) 1997-02-24
EP0662005B1 (en) 1998-04-29
HU9500876D0 (en) 1995-05-29
ATE165517T1 (en) 1998-05-15
DK0662005T3 (en) 1999-02-22
CN1089508A (en) 1994-07-20
ZA937099B (en) 1995-03-24
KR100287975B1 (en) 2001-05-02
NO307692B1 (en) 2000-05-15
ES2118251T3 (en) 1998-09-16
AU4959293A (en) 1994-04-26
HU221972B1 (en) 2003-03-28
TW394688B (en) 2000-06-21
NO951138D0 (en) 1995-03-24
EP0662005A1 (en) 1995-07-12
IL107108A (en) 1998-01-04
WO1994007539A1 (en) 1994-04-14
AU687360B2 (en) 1998-02-26
FI951379A0 (en) 1995-03-23
CN1078815C (en) 2002-02-06
DE4232755A1 (en) 1994-03-31
FI951379A (en) 1995-03-23
CA2145505C (en) 2004-02-17
CA2145505A1 (en) 1994-04-14
NO951138L (en) 1995-03-24
JPH08504398A (en) 1996-05-14

Similar Documents

Publication Publication Date Title
IL107108A0 (en) Microcapsules,processes for the preparation thereof and contrast compositions containing the same
CA2041260A1 (en) Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents
NO20002788D0 (en) New connections
CA2212058A1 (en) Preparation and use of a specific gaba-a.alpha.5 receptor ligand for treatment of alzheimer's disease
ZA965294B (en) Substituted 4-phenylaminothiazoles, their process of preparation and the pharmaceutical compositions containing them.
CA2180816A1 (en) 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients
CA2193337A1 (en) 1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients
MX9704030A (en) 2-heterocyclyloxy and thiomethyl-1,2,5-thiadiazolidin-3-one 1,1-dioxides and compositions and method of use thereof.
EP2270046A3 (en) Methods and compositions for the treatment of hemolysis-associated diseases
CA2149329A1 (en) Therapeutic application of chimeric and radiolabeled antibodies to human b lymphocyte restricted differentiation antigen for treatment of b cell lymphoma
HU9701416D0 (en) Phenyl-substituted guanidides of alkenyl-carboxylic acids, process for producing them, their use as medicine or diagnostics, and pharmaceutical compositions containing them
GR3022510T3 (en) Lyospheres comprising gonadotropin
SI0771788T1 (en) Substituted sulphonimidamides, method for their preparation, their use as medicament or diagnostic and medicament containing them
AU3892593A (en) Composition for therapeutic or diagnostic use, process for its preparation and its use
MY128260A (en) Cyclopentane-and-pentene-b-amino acids
ZA963893B (en) Substituted benzyloxycarbonylguanidines, process for their preparation, their use as a medicament of diagnostic, and medicament containing them.
ZA966047B (en) Therapeutic agents.
MY113431A (en) Substituted benzenesulfonylureas and -thioureas, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
MY114693A (en) Substituted benzenesulfonylureas and thioureas,processes for their preparation,their use for the production of pharmaceutical preparations, and pharmaceutical preparation containing them
HU9601976D0 (en) 4-fluoralkyl benzoylguanidines, process for producing them, their use for producing pharmaceutical or diagnostic compositions, and pharmaceutical compositions containing these compounds
IL109108A0 (en) Salts of (s)-alpha- phenyl - 2 - pyridineethanamine, their preparation and pharmaceutical compositions containing them
MY113432A (en) Substituted benzenesulfonylureas and -thioureas, processes for their preparation, their use for the production of pharmaceutical preparations, and medicaments containing them
MY113423A (en) Substituted thiophenesulfonylureas and -thioureas processes for their preparation, their use as amedicament or diagnostic, and medicament contiaining them
GR3020172T3 (en) Sterilant mixture and sterilization method.
EP0622363A3 (en) 2-amino-5-cyano-4-quinolyldihydropyridine esters, process for their preparation and their use in medicine for the treatment of heart-circulatory illnesses.

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
RH1 Patent not in force