NO307692B1 - Microcapsules made from biodegradable blend polymers, process for the preparation of the microcapsules and contrast agent - Google Patents

Microcapsules made from biodegradable blend polymers, process for the preparation of the microcapsules and contrast agent

Info

Publication number
NO307692B1
NO307692B1 NO951138A NO951138A NO307692B1 NO 307692 B1 NO307692 B1 NO 307692B1 NO 951138 A NO951138 A NO 951138A NO 951138 A NO951138 A NO 951138A NO 307692 B1 NO307692 B1 NO 307692B1
Authority
NO
Norway
Prior art keywords
microcapsules
preparation
contrast agent
blend polymers
biodegradable blend
Prior art date
Application number
NO951138A
Other languages
Norwegian (no)
Other versions
NO951138D0 (en
NO951138L (en
Inventor
Thomas Fritzsch
Dieter Heldmann
Werner Weitschies
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO951138D0 publication Critical patent/NO951138D0/en
Publication of NO951138L publication Critical patent/NO951138L/en
Publication of NO307692B1 publication Critical patent/NO307692B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels

Abstract

The invention concerns microparticle preparations made from biodegradable copolymers for therapeutic and diagnostic use, in particular for ultrasonic examinations, plus a method of producing such preparations.
NO951138A 1992-09-26 1995-03-24 Microcapsules made from biodegradable blend polymers, process for the preparation of the microcapsules and contrast agent NO307692B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4232755A DE4232755A1 (en) 1992-09-26 1992-09-26 Microparticle preparations made from biodegradable copolymers
PCT/EP1993/002422 WO1994007539A1 (en) 1992-09-26 1993-09-08 Microparticle preparations made from biodegradable copolymers

Publications (3)

Publication Number Publication Date
NO951138D0 NO951138D0 (en) 1995-03-24
NO951138L NO951138L (en) 1995-03-24
NO307692B1 true NO307692B1 (en) 2000-05-15

Family

ID=6469216

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951138A NO307692B1 (en) 1992-09-26 1995-03-24 Microcapsules made from biodegradable blend polymers, process for the preparation of the microcapsules and contrast agent

Country Status (18)

Country Link
EP (1) EP0662005B1 (en)
JP (1) JPH08504398A (en)
KR (1) KR100287975B1 (en)
CN (1) CN1078815C (en)
AT (1) ATE165517T1 (en)
AU (1) AU687360B2 (en)
CA (1) CA2145505C (en)
DE (2) DE4232755A1 (en)
DK (1) DK0662005T3 (en)
ES (1) ES2118251T3 (en)
FI (1) FI117124B (en)
HU (1) HU221972B1 (en)
IL (1) IL107108A (en)
NO (1) NO307692B1 (en)
NZ (1) NZ255409A (en)
TW (1) TW394688B (en)
WO (1) WO1994007539A1 (en)
ZA (1) ZA937099B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
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US5922304A (en) * 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US6333021B1 (en) * 1994-11-22 2001-12-25 Bracco Research S.A. Microcapsules, method of making and their use
EP0727225A3 (en) * 1995-02-14 1997-01-15 Sonus Pharma Inc Compositions and methods for directed ultrasound imaging
DE19510690A1 (en) 1995-03-14 1996-09-19 Schering Ag Polymeric nano- and / or microparticles, processes for their production, and use in medical diagnostics and therapy
EP1444991A1 (en) * 1995-06-07 2004-08-11 Imarx Pharmaceutical Corp. Novel targeted compositions for diagnostic and therapeutic use
US6821506B2 (en) 1995-06-08 2004-11-23 Barnes-Jewish Hospital Site specific binding system, imaging compositions and methods
US5780010A (en) * 1995-06-08 1998-07-14 Barnes-Jewish Hospital Method of MRI using avidin-biotin conjugated emulsions as a site specific binding system
US6548046B1 (en) 1995-06-08 2003-04-15 Barnes-Jewish Hospital Site specific binding system, imaging compositions and methods
AU1354497A (en) * 1995-12-21 1997-07-14 Drexel University Hollow polymer microcapsules and method of producing
US5849727A (en) * 1996-06-28 1998-12-15 Board Of Regents Of The University Of Nebraska Compositions and methods for altering the biodistribution of biological agents
US6261537B1 (en) 1996-10-28 2001-07-17 Nycomed Imaging As Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors
US6331289B1 (en) 1996-10-28 2001-12-18 Nycomed Imaging As Targeted diagnostic/therapeutic agents having more than one different vectors
WO1998018498A2 (en) * 1996-10-28 1998-05-07 Marsden, John, Christopher Improvements in or relating to diagnostic/therapeutic agents
CA2270120A1 (en) 1996-10-28 1998-05-07 Pal Rongved Improvements in or relating to diagnostic/therapeutic agents
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
DE19925311B4 (en) * 1999-05-27 2004-06-09 Schering Ag Multi-stage process for the production of gas-filled microcapsules
US7220401B2 (en) 1999-09-24 2007-05-22 Barnes-Jewish Hospital Blood clot-targeted nanoparticles
DE10013850A1 (en) * 2000-03-15 2001-09-20 Schering Ag Gas-filled microcapsules, useful for ultrasonic diagnosis, are prepared from functionalized poly(alkyl cyanoacrylate), allowing attachment of e.g. specific-binding agents
DE10119522A1 (en) * 2001-04-20 2002-12-05 Innovacell Biotechnologie Gmbh Preparation and application of a suspension composition with an ultrasound contrast medium
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US7901770B2 (en) 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
ATE530666T1 (en) 2004-11-03 2011-11-15 Iris Molecular Diagnostics Inc MICROBUBBLES FOR AFFINITY SEPARATION
EP1842226B2 (en) 2004-11-03 2014-07-02 Iris International, Inc. Homogeneous analyte detection
US7727555B2 (en) 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
KR100845010B1 (en) * 2007-08-29 2008-07-08 한국생명공학연구원 Polymer particles for nir/mr bimodal molecular imaging and method for preparing thereof
CN101518780B (en) * 2008-12-31 2011-09-14 广东省生态环境与土壤研究所 Complexing agent microcapsule for plant soil restoration and preparation method thereof
EP2474327A1 (en) * 2011-01-07 2012-07-11 RWTH Aachen Microdosing of ultrasound contrast agents

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989006978A1 (en) * 1988-02-05 1989-08-10 Schering Aktiengesellschaft Berlin Und Bergkamen Ultrasonic contrast agents, process for producing them and their use as diagnostic and therapeutic agents
DE4004430A1 (en) * 1990-02-09 1991-08-14 Schering Ag CONSTRUCTED POLYALDEHYDE CONSTITUENTS
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
GB9106686D0 (en) * 1991-03-28 1991-05-15 Hafslund Nycomed As Improvements in or relating to contrast agents

Also Published As

Publication number Publication date
CA2145505A1 (en) 1994-04-14
ES2118251T3 (en) 1998-09-16
NO951138D0 (en) 1995-03-24
DK0662005T3 (en) 1999-02-22
EP0662005B1 (en) 1998-04-29
CN1078815C (en) 2002-02-06
IL107108A0 (en) 1993-12-28
DE59308479D1 (en) 1998-06-04
CA2145505C (en) 2004-02-17
HU221972B1 (en) 2003-03-28
AU687360B2 (en) 1998-02-26
JPH08504398A (en) 1996-05-14
AU4959293A (en) 1994-04-26
EP0662005A1 (en) 1995-07-12
WO1994007539A1 (en) 1994-04-14
TW394688B (en) 2000-06-21
KR100287975B1 (en) 2001-05-02
FI951379A (en) 1995-03-23
FI951379A0 (en) 1995-03-23
HU9500876D0 (en) 1995-05-29
HUT71683A (en) 1996-01-29
NZ255409A (en) 1997-02-24
IL107108A (en) 1998-01-04
DE4232755A1 (en) 1994-03-31
KR950703367A (en) 1995-09-20
CN1089508A (en) 1994-07-20
FI117124B (en) 2006-06-30
ATE165517T1 (en) 1998-05-15
ZA937099B (en) 1995-03-24
NO951138L (en) 1995-03-24

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