DE69427588D1 - HUMANE PROTEIN-TYROSINPHOSPHATASE DECODIERENDE cDNA - Google Patents

HUMANE PROTEIN-TYROSINPHOSPHATASE DECODIERENDE cDNA

Info

Publication number
DE69427588D1
DE69427588D1 DE69427588T DE69427588T DE69427588D1 DE 69427588 D1 DE69427588 D1 DE 69427588D1 DE 69427588 T DE69427588 T DE 69427588T DE 69427588 T DE69427588 T DE 69427588T DE 69427588 D1 DE69427588 D1 DE 69427588D1
Authority
DE
Germany
Prior art keywords
ptp
cdna
tyrosinphosphatase
humane
decoding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69427588T
Other languages
English (en)
Other versions
DE69427588T2 (de
Inventor
Gideon A Rodan
Su J Rutledge
Azriel Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of DE69427588D1 publication Critical patent/DE69427588D1/de
Publication of DE69427588T2 publication Critical patent/DE69427588T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/42Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69427588T 1993-09-14 1994-09-09 HUMANE PROTEIN-TYROSINPHOSPHATASE DECODIERENDE cDNA Expired - Fee Related DE69427588T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12203293A 1993-09-14 1993-09-14
PCT/US1994/010166 WO1995007935A1 (en) 1993-09-14 1994-09-09 cDNA ENCODING A NOVEL HUMAN PROTEIN TYROSINE PHOSPHATASE

Publications (2)

Publication Number Publication Date
DE69427588D1 true DE69427588D1 (de) 2001-08-02
DE69427588T2 DE69427588T2 (de) 2002-04-25

Family

ID=22400183

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427588T Expired - Fee Related DE69427588T2 (de) 1993-09-14 1994-09-09 HUMANE PROTEIN-TYROSINPHOSPHATASE DECODIERENDE cDNA

Country Status (8)

Country Link
US (3) US5658756A (de)
EP (1) EP0725800B1 (de)
JP (1) JPH09502614A (de)
AT (1) ATE202571T1 (de)
CA (1) CA2171610A1 (de)
DE (1) DE69427588T2 (de)
ES (1) ES2157991T3 (de)
WO (1) WO1995007935A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821084A (en) * 1994-11-21 1998-10-13 The Regents Of The University Of Michigan Osteoblast-testicular protein tyrosine phosphatase
IL117175A (en) 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
US6919434B1 (en) 1995-02-20 2005-07-19 Sankyo Co., Ltd. Monoclonal antibodies that bind OCIF
US5719058A (en) * 1995-04-10 1998-02-17 Merck & Co., Inc. Method for producing a highly enriched population of osteoclast cells
ATE298566T1 (de) 1995-09-11 2005-07-15 Osteoarthritis Sciences Inc Proteintyrosine-kinaseinhibitoren zur behandlung der osteoarthritis
US7632922B1 (en) * 1995-12-22 2009-12-15 Amgen, Inc. Osteoprotegerin
US20050147611A1 (en) * 1995-12-22 2005-07-07 Amgen Inc. Combination therapy for conditions leading to bone loss
EP0951551B9 (de) 1996-12-23 2012-12-26 Immunex Corporation Ligand für rezeptor aktivator of nf-kappa b, ligand ist mitglied der tnf superfamilie
NZ332995A (en) * 1997-04-15 2000-07-28 Snow Brand Milk Products Co Ltd A protein which binds to osteoclastogenesis inhibitory factor (OCIF)
ES2284203T5 (es) 1997-04-16 2016-03-11 Amgen Inc. Proteínas de unión a osteoprotegerina y sus receptores
US6316408B1 (en) * 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
WO1998054357A1 (en) * 1997-05-30 1998-12-03 David Jeston Baylink SCREENING METHODS TO IDENTIFY COMPOUNDS WHICH EFFECT OSTEOCLAST-SPECIFIC PHOSPHOTYROSYL PHOSPHATASE (PTP-oc) ACTIVITY
HUP0002062A3 (en) 1997-09-24 2002-09-30 Sankyo Co Method for diagnosing bone dysbolism
JP4520634B2 (ja) 1997-10-24 2010-08-11 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション 良性の家族性新生児痙攣(bfnc)および他の癲癇において突然変異されたkcnq2およびkcnq3−カリウムチャンネル遺伝子
US6780596B2 (en) * 1998-09-17 2004-08-24 Ashni Naturaceuticals, Inc. Methods for determining the activity of complex mixtures
US6331533B1 (en) 1998-11-16 2001-12-18 Merck & Co., Inc. Method for inhibiting dental resorptive lesions
AU2900400A (en) 1999-03-08 2000-09-28 Merck Frosst Canada & Co. Intact cell assay for protein tyrosine phosphatases
US20030103978A1 (en) * 2000-02-23 2003-06-05 Amgen Inc. Selective binding agents of osteoprotegerin binding protein
NZ526133A (en) * 2001-03-30 2005-08-26 Us Health Geldanamycin derivative and method of treating cancer using same
US7247618B2 (en) * 2001-04-30 2007-07-24 Tripathi Rajavashisth Methods for inhibiting macrophage colony stimulating factor and c-FMS-dependent cell signaling
PL375041A1 (en) 2002-04-05 2005-11-14 Amgen Inc. Human anti-opgl neutralizing antibodies as selective opgl pathway inhibitors
US20040186151A1 (en) * 2003-02-12 2004-09-23 Mjalli Adnan M.M. Substituted azole derivatives as therapeutic agents
CA2514363A1 (en) * 2003-02-12 2004-08-26 Transtech Pharma, Inc. Substituted azole derivatives as therapeutic agents
EP1730118A1 (de) * 2004-02-12 2006-12-13 Transtech Pharma, Inc. Substituierte azolderivate, zusammensetzungen und anwendungsverfahren
ZA200805648B (en) 2006-01-30 2009-09-30 Transtech Pharma Inc Substituted imidazole derivatives and their use as PTPase inhibitors
US11119095B2 (en) * 2015-10-06 2021-09-14 Tokyo Institute Of Technology Method for measuring tyrosine phosphatase and tyrosine kinase activity

Also Published As

Publication number Publication date
JPH09502614A (ja) 1997-03-18
EP0725800B1 (de) 2001-06-27
ES2157991T3 (es) 2001-09-01
US6214564B1 (en) 2001-04-10
WO1995007935A1 (en) 1995-03-23
DE69427588T2 (de) 2002-04-25
EP0725800A4 (de) 1997-09-10
ATE202571T1 (de) 2001-07-15
CA2171610A1 (en) 1995-03-23
EP0725800A1 (de) 1996-08-14
US5866397A (en) 1999-02-02
US5658756A (en) 1997-08-19

Similar Documents

Publication Publication Date Title
DE69427588D1 (de) HUMANE PROTEIN-TYROSINPHOSPHATASE DECODIERENDE cDNA
LU92977I2 (fr) Odomzo, sonifégib et ses sels, en particulier son phosphate
DE69637669D1 (de) Myogene differenzierung menschlicher mesenchymaler stammzellen
ATE103932T1 (de) Fusionsprotein bestehend aus gm-csf und il-3.
DE59611411D1 (de) Verwendung von alpha 1l-agonisten zur behandlung der harninkontinenz
ATE271041T1 (de) Analoga von duocarmycin and cc-1065
YU46806B (sh) 5-FLUORO-2-//(4-CIKLOPROPILMETOKSI-2-PIRINIDIL)METILSULFINIL/1h-BENZIMODAZOL I POSTUPAK ZA NJEGOVO DOBIJANJE
ZA981936B (en) Novel benzimidazole inhibitors of fructose 1,6-bisphosphatase.
PT975359E (pt) Potencializacao da resposta imunitaria atraves de distribuicao de compostos que se ligam a uma dipeptidase citoplasmatica
FR2631228B1 (fr) Implant intra-oculaire de chambre anterieure
DE59609235D1 (de) Verwendung von aerogelen in der landwirtschaft
HUP0004544A2 (hu) Angiotenzin-átalakító enzim inhibitora és diuretikum kombinációjának alkalmazása mikrokeringési rendellenességek kezelésére szolgáló gyógyászati készítmény előállítására
DE68917324T2 (de) Methode zur Immobilisierung von physiologisch aktiven Substanzen.
UA26431A (uk) Похідhі сиh-ізомеру цефалоспориhу, їх оптичhо активhі аhтиподи або рацемічhа суміш, а також їх фармацевтичhо прийhятhі кислотhо-адитивhі солі
ATE330620T1 (de) Verwendung von midkin oder von anti-midkin antikörper
DE59706450D1 (de) Pharmazeutische zusammensetzung enthaltend lornoxicam und ein dinatriumsalz der edta
BR9609081A (pt) Combinações de substáncias ativas
ES2124235T3 (es) Uso de tri(n-butil) fosfato a bajo ph en soluciones de proteinas biologicamente activas para mejorar la actividad viricida.
DE69637676D1 (de) Verwendung von lokal verabreichten Lysine zur VERBESSERUNG DER VASKULAREN FUNKTION
AU6688696A (en) Non-receptor type human protein tyrosine phosphatase
PT832069E (pt) Derivados de tetrahidro-isoquinolin-6-il amida do acido bifenilo-2-carboxilico sua preparacao e sua utilizacao como inibidores de proteina de transferencia de triglicerido microsomal e/ou da secrecao de apolipoproteina b (apo b)
KR950702251A (ko) 치주질환병원체 세균의 단백질 분해활성을 측정하기 위한 시스템(System for measuring proteolytic activity of periodontopathogenic bacteria)
YU48719B (sh) Lizin so 6-hloro-5-fluoro-3-(2-tenoil)-2-oksindol-1-karboksamida
ATE210605T1 (de) Verwendung von sulfonamiden zur kontrolle von biobewuchs
ES2186782T3 (es) Uso de derivados de tropolona como inhibidores de la enzima inositol-monofosfatasa.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee