DE69425131D1 - Verwendung von clavulansäure und einem antibiotikum zur behandlung von infektionen - Google Patents

Verwendung von clavulansäure und einem antibiotikum zur behandlung von infektionen

Info

Publication number
DE69425131D1
DE69425131D1 DE69425131T DE69425131T DE69425131D1 DE 69425131 D1 DE69425131 D1 DE 69425131D1 DE 69425131 T DE69425131 T DE 69425131T DE 69425131 T DE69425131 T DE 69425131T DE 69425131 D1 DE69425131 D1 DE 69425131D1
Authority
DE
Germany
Prior art keywords
clavulic
antibiotic
acid
treating infections
infections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69425131T
Other languages
English (en)
Other versions
DE69425131T2 (de
Inventor
Gillian Marjory Smith
Christine Elaine Thorburn
Karen Hazel Abbott
Tim Neilc Smithkline Bee Brown
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939301250A external-priority patent/GB9301250D0/en
Priority claimed from GB939302908A external-priority patent/GB9302908D0/en
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of DE69425131D1 publication Critical patent/DE69425131D1/de
Publication of DE69425131T2 publication Critical patent/DE69425131T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69425131T 1993-01-22 1994-01-21 Verwendung von clavulansäure und einem antibiotikum zur behandlung von infektionen Expired - Lifetime DE69425131T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB939301250A GB9301250D0 (en) 1993-01-22 1993-01-22 Pharmaceutical formulations
GB939302908A GB9302908D0 (en) 1993-02-13 1993-02-13 Pharmaceutical formulations
PCT/GB1994/000124 WO1994016696A1 (en) 1993-01-22 1994-01-21 Pharmaceutical formulations comprising clavulanic acid alone or in combination with other beta-lactam antibiotics

Publications (2)

Publication Number Publication Date
DE69425131D1 true DE69425131D1 (de) 2000-08-10
DE69425131T2 DE69425131T2 (de) 2001-03-15

Family

ID=26302329

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69425131T Expired - Lifetime DE69425131T2 (de) 1993-01-22 1994-01-21 Verwendung von clavulansäure und einem antibiotikum zur behandlung von infektionen

Country Status (5)

Country Link
EP (2) EP1034784A3 (de)
JP (1) JPH08505868A (de)
AU (1) AU5863894A (de)
DE (1) DE69425131T2 (de)
WO (1) WO1994016696A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DZ1926A1 (fr) * 1994-09-03 2002-02-17 Smithkline Beckman P L C Formulations pharmaceutiques.
TR199800415T1 (en) 1995-09-07 1998-05-21 Smithkline Beecham Corporation Farmas�tik form�lasyon.
WO1998035672A1 (en) * 1997-02-14 1998-08-20 Smithkline Beecham Laboratoires Pharmaceutiques Pharmaceutical formulations comprising amoxocyllin and clavulanate
US6177421B1 (en) 1999-05-04 2001-01-23 Fuisz International Ltd. Amoxicillin and clavulanate composition
IE990159A1 (en) * 1999-02-26 2000-09-20 Fuisz Internat Ltd Storage Stable Amoxycillin and Clavulanate Suspension Composition.
US7250176B1 (en) 1999-04-13 2007-07-31 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection
US6294199B1 (en) * 1999-04-13 2001-09-25 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising administering amoxycillin
US6878386B1 (en) 1999-04-13 2005-04-12 Beecham Pharmaceuticals (Pte) Limited Method of treating a bacterial infection comprising amoxycillin and potassium clavulanate
BG65006B1 (bg) * 1999-04-13 2006-12-29 Beecham Pharmaceuticals (Pte) Limited Фармацевтични форми, съдържащи високи дози амоксицилин и калиев клавуланат
US6756057B2 (en) 2000-10-12 2004-06-29 Beecham Pharmaceuticals (Pte) Limited Amoxicillin and potassium clavulanate dosage form
EP1330236A2 (de) 2000-10-12 2003-07-30 Beecham Pharmaceuticals (Pte) Limited Amoxicillinhaltige arzneizusammensetzungen
WO2007086012A1 (en) * 2006-01-25 2007-08-02 Jegannathan Srinivas Formulation of cefpodoxime, clavulanic acid and linezolid
TR201000688A2 (tr) 2010-01-29 2011-08-22 B�Lg�� Mahmut Aktif madde olarak sefaklor ve klavulanik asit içeren efervesan formülasyonlar.
TR201000687A1 (tr) 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
EP2575781A1 (de) * 2010-06-03 2013-04-10 Mahmut Bilgic Verfahren zur herstellung einer brauseformulierung mit cephalosporin und kalium-clavulanat
WO2013109201A1 (en) * 2012-01-18 2013-07-25 Mahmut Bilgic Pharmaceutical compositions comprising cefprozil and clavulanic acid
US20150258072A1 (en) * 2012-09-03 2015-09-17 Wockhardt Limited Antibacterial compositions
EP2727591A3 (de) * 2012-10-31 2014-08-13 Kücükgüzel, Sükriye Güniz Stabile pharmazeutische Zusammensetzungen mit Cefaclor und Clavulansäure
EP3484472A1 (de) * 2016-07-14 2019-05-22 Achaogen, Inc. Kombination aus ceftibuten und clavulansäure zur verwendung in der behandlung von bakteriellen infektionen
CN113350337B (zh) * 2021-07-07 2022-07-19 中国海洋大学 一种用于抑制多药耐药细菌的克拉维酸和氨曲南的组合物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41109B1 (en) * 1974-04-20 1979-10-24 Beecham Group Ltd Novel -lactam antibiotic from streptomyces clavuligerus

Also Published As

Publication number Publication date
DE69425131T2 (de) 2001-03-15
EP0680322B1 (de) 2000-07-05
JPH08505868A (ja) 1996-06-25
AU5863894A (en) 1994-08-15
EP1034784A3 (de) 2001-06-27
EP1034784A2 (de) 2000-09-13
WO1994016696A1 (en) 1994-08-04
EP0680322A1 (de) 1995-11-08

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