DE69423055T2 - Indol Derivate als Glutamat Antagonisten - Google Patents

Indol Derivate als Glutamat Antagonisten

Info

Publication number
DE69423055T2
DE69423055T2 DE69423055T DE69423055T DE69423055T2 DE 69423055 T2 DE69423055 T2 DE 69423055T2 DE 69423055 T DE69423055 T DE 69423055T DE 69423055 T DE69423055 T DE 69423055T DE 69423055 T2 DE69423055 T2 DE 69423055T2
Authority
DE
Germany
Prior art keywords
glutamate antagonists
indole derivatives
independently
compounds
antagonists
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69423055T
Other languages
English (en)
Other versions
DE69423055D1 (de
Inventor
Frank Waetjen
Jorgen Drejer
Leif Helth Jensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NTG Nordic Transport Group AS
Original Assignee
Neurosearch AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch AS filed Critical Neurosearch AS
Application granted granted Critical
Publication of DE69423055D1 publication Critical patent/DE69423055D1/de
Publication of DE69423055T2 publication Critical patent/DE69423055T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Luminescent Compositions (AREA)
  • Conductive Materials (AREA)
DE69423055T 1993-06-14 1994-06-01 Indol Derivate als Glutamat Antagonisten Expired - Fee Related DE69423055T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93696A DK69693D0 (da) 1993-06-14 1993-06-14 Farven lilla

Publications (2)

Publication Number Publication Date
DE69423055D1 DE69423055D1 (de) 2000-03-30
DE69423055T2 true DE69423055T2 (de) 2000-08-03

Family

ID=8096489

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69423055T Expired - Fee Related DE69423055T2 (de) 1993-06-14 1994-06-01 Indol Derivate als Glutamat Antagonisten

Country Status (5)

Country Link
US (1) US5478859A (de)
EP (1) EP0629615B1 (de)
AT (1) ATE189889T1 (de)
DE (1) DE69423055T2 (de)
DK (2) DK69693D0 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565580A (en) * 1994-01-27 1996-10-15 Neurosearch A/S Glutamate Antagonists
US5824662A (en) * 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
EP1005348A1 (de) 1996-09-27 2000-06-07 Guilford Pharmaceuticals Inc. Naaladase zusammensetzungen und verfahren zur behandlung von glutamatabnormalien und der neuronalen aktivität in tieren
EP2140864A3 (de) * 2001-01-31 2010-01-27 H.Lundbeck A/S Verwendung von GAL3-Rezeptorantagonisten zur Behandlung von Depression und/oder Angstgefühl und Verbindungen, die in solchen Verfahren von Nutzen sind
US7642281B2 (en) 2002-08-07 2010-01-05 Helicon Therapeutics, Inc. Indolone compounds useful to treat cognitive impairment
WO2007070362A1 (en) * 2005-12-09 2007-06-21 Helicon Therapeutics, Inc. Indolone compounds useful to treat cognitive impairment

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE69677B1 (en) * 1989-12-11 1996-10-02 Neurosearch As Isatine derivatives their preparation and use
US5192792A (en) * 1990-12-07 1993-03-09 Warner-Lambert Company Isatine derivatives, and their method of use
US5164404A (en) * 1991-03-15 1992-11-17 Neurosearch A/S Hydrazone derivatives and their use
US5565580A (en) * 1994-01-27 1996-10-15 Neurosearch A/S Glutamate Antagonists

Also Published As

Publication number Publication date
DE69423055D1 (de) 2000-03-30
DK0629615T3 (da) 2000-07-03
EP0629615B1 (de) 2000-02-23
ATE189889T1 (de) 2000-03-15
DK69693D0 (da) 1993-06-14
EP0629615A1 (de) 1994-12-21
US5478859A (en) 1995-12-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee