ATE189889T1 - Indol derivate als glutamat antagonisten - Google Patents

Indol derivate als glutamat antagonisten

Info

Publication number
ATE189889T1
ATE189889T1 AT94610030T AT94610030T ATE189889T1 AT E189889 T1 ATE189889 T1 AT E189889T1 AT 94610030 T AT94610030 T AT 94610030T AT 94610030 T AT94610030 T AT 94610030T AT E189889 T1 ATE189889 T1 AT E189889T1
Authority
AT
Austria
Prior art keywords
glutamate antagonists
indole derivatives
independently
compounds
antagonists
Prior art date
Application number
AT94610030T
Other languages
English (en)
Inventor
Frank Waetjen
Jorgen Drejer
Leif Helth Jensen
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of ATE189889T1 publication Critical patent/ATE189889T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Conductive Materials (AREA)
  • Luminescent Compositions (AREA)
AT94610030T 1993-06-14 1994-06-01 Indol derivate als glutamat antagonisten ATE189889T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK93696A DK69693D0 (da) 1993-06-14 1993-06-14 Farven lilla

Publications (1)

Publication Number Publication Date
ATE189889T1 true ATE189889T1 (de) 2000-03-15

Family

ID=8096489

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94610030T ATE189889T1 (de) 1993-06-14 1994-06-01 Indol derivate als glutamat antagonisten

Country Status (5)

Country Link
US (1) US5478859A (de)
EP (1) EP0629615B1 (de)
AT (1) ATE189889T1 (de)
DE (1) DE69423055T2 (de)
DK (2) DK69693D0 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565580A (en) * 1994-01-27 1996-10-15 Neurosearch A/S Glutamate Antagonists
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) * 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
KR20000036227A (ko) 1996-09-27 2000-06-26 토마스 씨. 서 날라다아제조성물, 글루탐산염 이상 치료법 및 동물내의 뉴우런활성법
CZ20032341A3 (cs) * 2001-01-31 2004-12-15 Synaptic Pharmaceutical Corporation Použití antagonistů GAL3 receptoru pro léčbu deprese a/nebo úzkosti
US7642281B2 (en) 2002-08-07 2010-01-05 Helicon Therapeutics, Inc. Indolone compounds useful to treat cognitive impairment
SK500262008A3 (sk) * 2005-12-09 2009-03-05 Helicon Therapeutics, Inc. Použitie indolónových zlúčenín na výrobu lieku na liečenie zhoršenej poznávacej schopnosti

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE69677B1 (en) * 1989-12-11 1996-10-02 Neurosearch As Isatine derivatives their preparation and use
US5192792A (en) * 1990-12-07 1993-03-09 Warner-Lambert Company Isatine derivatives, and their method of use
US5164404A (en) * 1991-03-15 1992-11-17 Neurosearch A/S Hydrazone derivatives and their use
US5565580A (en) * 1994-01-27 1996-10-15 Neurosearch A/S Glutamate Antagonists

Also Published As

Publication number Publication date
DK69693D0 (da) 1993-06-14
EP0629615A1 (de) 1994-12-21
DK0629615T3 (da) 2000-07-03
DE69423055T2 (de) 2000-08-03
US5478859A (en) 1995-12-26
DE69423055D1 (de) 2000-03-30
EP0629615B1 (de) 2000-02-23

Similar Documents

Publication Publication Date Title
ATE248824T1 (de) Substituierte phenylderivate, ihre herstellung und verwendung
DE69813605D1 (de) Benzofuranderivate
ES2181853T3 (es) Tratamiento del tinnitus empleando agentes neuroprotectores.
ATE163648T1 (de) Indole derivate als serotonin-antagonisten
ATE230392T1 (de) Amidinophenyl-pyrrolidine, -pyrroline und - isoxazolidine und ihre derivate
DE69505470D1 (de) Pyrrolocarbazol
TR199902546T2 (xx) Serotoninerjik maddeler olarak indazol amit bile�ikleri.
EP1031556A4 (de) 2-phenoxyanilin-derivate
KR950701615A (ko) 혈소판 응집 저해작용을 갖는 신규한 화합물(novel compound with plate-let aggregation inhibitor activity)
DE69423055D1 (de) Indol Derivate als Glutamat Antagonisten
EP1034783A4 (de) Amidederivaten
DE69430839D1 (de) Trizyklische Indol-2-carbonsäure Derivate als selektive NMDA Rezeptor Antagonisten
CA2427573A1 (en) Indole derivatives as pde5-inhibitors
ITMI930819A1 (it) Derivati eterobiciclici ad attivita' fungicida
BR9902096A (pt) Pitazóis.
ATE197953T1 (de) Pyrrolo(4,3,2-de)chinolin-derivat
DE69231244D1 (de) Pyrazolothiazolopyrimidin-derivate
ES2182775T3 (es) Derivados de ciclohexano 1,4-disustituidos para el tratamiento de la depresion.
EP0782988A4 (de) Indol-derivate
EP1325913A3 (de) Piperidincarbonsäuramid-Derivate

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee