DE69420454T2 - Interne Kontrollen für isotherme Nukleinsäure-Amplifizierungsreaktionen - Google Patents

Interne Kontrollen für isotherme Nukleinsäure-Amplifizierungsreaktionen

Info

Publication number
DE69420454T2
DE69420454T2 DE69420454T DE69420454T DE69420454T2 DE 69420454 T2 DE69420454 T2 DE 69420454T2 DE 69420454 T DE69420454 T DE 69420454T DE 69420454 T DE69420454 T DE 69420454T DE 69420454 T2 DE69420454 T2 DE 69420454T2
Authority
DE
Germany
Prior art keywords
nucleic acid
acid amplification
amplification reactions
internal controls
isothermal nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69420454T
Other languages
English (en)
Other versions
DE69420454D1 (de
Inventor
James G Nadeau
Michael C Little
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of DE69420454D1 publication Critical patent/DE69420454D1/de
Application granted granted Critical
Publication of DE69420454T2 publication Critical patent/DE69420454T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6865Promoter-based amplification, e.g. nucleic acid sequence amplification [NASBA], self-sustained sequence replication [3SR] or transcription-based amplification system [TAS]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69420454T 1993-05-05 1994-04-28 Interne Kontrollen für isotherme Nukleinsäure-Amplifizierungsreaktionen Expired - Lifetime DE69420454T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/058,648 US5457027A (en) 1993-05-05 1993-05-05 Internal controls for isothermal nucleic acid amplification reactions

Publications (2)

Publication Number Publication Date
DE69420454D1 DE69420454D1 (de) 1999-10-14
DE69420454T2 true DE69420454T2 (de) 1999-12-23

Family

ID=22018080

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69420454T Expired - Lifetime DE69420454T2 (de) 1993-05-05 1994-04-28 Interne Kontrollen für isotherme Nukleinsäure-Amplifizierungsreaktionen

Country Status (8)

Country Link
US (2) US5457027A (de)
EP (1) EP0623682B1 (de)
JP (1) JP3127079B2 (de)
AU (1) AU675503B2 (de)
CA (1) CA2121658C (de)
DE (1) DE69420454T2 (de)
ES (1) ES2136137T3 (de)
SG (1) SG50707A1 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA936015B (en) * 1992-08-24 1994-03-10 Akzo Nv Elimination of false negatives in nuleic acid detection.
US5470723A (en) 1993-05-05 1995-11-28 Becton, Dickinson And Company Detection of mycobacteria by multiplex nucleic acid amplification
US5457027A (en) * 1993-05-05 1995-10-10 Becton, Dickinson And Company Internal controls for isothermal nucleic acid amplification reactions
AT401270B (de) * 1994-09-26 1996-07-25 Immuno Ag Verfahren zur quantifizierung von genomischer dna
US5705365A (en) * 1995-06-07 1998-01-06 Gen-Probe Incorporated Kits for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
JP3996639B2 (ja) * 1995-06-07 2007-10-24 ジェン−プローブ・インコーポレーテッド 生成物の増幅後レベルから核酸標的配列の増幅前レベルを決定するための方法とキット
US5710029A (en) * 1995-06-07 1998-01-20 Gen-Probe Incorporated Methods for determining pre-amplification levels of a nucleic acid target sequence from post-amplification levels of product
US5882867A (en) * 1995-06-07 1999-03-16 Dade Behring Marburg Gmbh Detection of nucleic acids by formation of template-dependent product
US5736333A (en) * 1996-06-04 1998-04-07 The Perkin-Elmer Corporation Passive internal references for the detection of nucleic acid amplification products
IL124275A (en) * 1997-05-02 2002-03-10 Bio Merieux Vitek Inc A method to produce sequences of nucleic acids
US6558901B1 (en) * 1997-05-02 2003-05-06 Biomerieux Vitek Nucleic acid assays
US6289229B1 (en) 1998-01-20 2001-09-11 Scimed Life Systems, Inc. Readable probe array for in vivo use
US6365346B1 (en) * 1998-02-18 2002-04-02 Dade Behring Inc. Quantitative determination of nucleic acid amplification products
US6066458A (en) * 1998-05-18 2000-05-23 Becton, Dickinson And Company Methods, apparatus and computer program products for determining quantities of nucleic acid sequences in samples using standard curves and amplification ratio estimates
IT1303767B1 (it) 1998-11-17 2001-02-23 San Raffaele Centro Fond Metodo di quantificazione di acidi nucleici.
US8012719B2 (en) 1998-11-17 2011-09-06 Paolo Lusso Method for the quantitative detection of nucleic acids
AU2410500A (en) * 1999-01-11 2000-08-01 President And Fellows Of Harvard College Isothermal amplification of dna
US6235479B1 (en) 1999-04-13 2001-05-22 Bio Merieux, Inc. Methods and devices for performing analysis of a nucleic acid sample
DE60022541T2 (de) 1999-07-23 2006-06-14 Gen Probe Inc Polynukleotid- amplifikationsverfahren
US7271781B2 (en) * 2000-03-03 2007-09-18 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Multiplex hybridization system for identification of pathogenic mycobacterium and method of use
EP1236804A1 (de) * 2001-03-02 2002-09-04 Boehringer Mannheim Gmbh Verfahren zur Bestimmung von Nukleinsäuren mittels einer Kontrolle
EP1236805B1 (de) * 2001-03-02 2008-05-07 Roche Diagnostics GmbH Verfahren zur Bestimmung von Nukleinsäuren mittels einer Kontrolle
EP1423534A4 (de) * 2001-08-16 2006-08-30 Stratagene California Kontrollnukleinsäuren enthaltende zusammensetzungen und verfahren
AU2003208959A1 (en) * 2002-01-30 2003-09-02 Id Biomedical Corporation Methods for detecting vancomycin-resistant microorganisms and compositions therefor
EP1540011B1 (de) * 2002-07-26 2010-01-06 Abbott Laboratories Verfahren zum nachweis und zur quantifizierung von hepatitis-c-virus
US20040024193A1 (en) * 2002-07-26 2004-02-05 Williams Gregg T. Method of detecting and quantifying hepatitis C virus
CA2522062C (en) * 2003-04-11 2011-03-29 Dna Landmarks Inc. Methods for relative quantification of specific nucleic acid sequences
WO2004094456A2 (en) 2003-04-18 2004-11-04 Becton, Dickinson And Company Immuno-amplification
WO2004097046A1 (en) * 2003-05-01 2004-11-11 Isis Innovation Limited Stable internal standard for pcr and rt- pcr reactions
US7229800B2 (en) * 2004-04-16 2007-06-12 Becton, Dickinson And Company Neisseria gonorrhoeae assay
AU2005291899A1 (en) 2004-09-30 2006-04-13 Gen-Probe Incorporated Assay for detecting and quantifying HIV-1
EP2333561A3 (de) 2005-03-10 2014-06-11 Gen-Probe Incorporated System zum Durchführen von Tests in mehreren Formaten
JP2010511390A (ja) 2006-11-30 2010-04-15 ジェン−プロウブ インコーポレイテッド 予め規定されたマスター検量線の調整を使用する定量方法
US20080274458A1 (en) * 2007-05-01 2008-11-06 Latham Gary J Nucleic acid quantitation methods
US9689031B2 (en) 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
WO2010139767A1 (de) * 2009-06-04 2010-12-09 Qiagen Gmbh Amplifikation komplexer nukleinsäuren
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
ES2576927T3 (es) 2010-10-22 2016-07-12 T2 Biosystems, Inc. Sistemas de RMN y métodos para la detección rápida de analitos
US9738924B2 (en) 2011-12-22 2017-08-22 Centre National De La Recherche Scientifique (Cnrs) Method of DNA detection and quantification by single-molecule hybridization and manipulation
US9932628B2 (en) 2012-07-27 2018-04-03 Gen-Probe Incorporated Dual reference calibration method and system for quantifying polynucleotides
US20140193819A1 (en) * 2012-10-31 2014-07-10 Becton, Dickinson And Company Methods and compositions for modulation of amplification efficiency
EP2981618B1 (de) 2013-04-01 2019-08-28 Becton, Dickinson and Company Verfahren und kits zur diagnose von influenza
US20180148778A1 (en) * 2014-12-16 2018-05-31 Garvan Institute Of Medical Research Sequencing controls
WO2017127727A1 (en) 2016-01-21 2017-07-27 T2 Biosystems, Inc. Rapid antimicrobial susceptibility testing using high-sensitivity direct detection methods
CA3020581A1 (en) 2016-04-14 2017-10-19 T2 Biosystems, Inc. Methods and systems for amplification in complex samples

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0461155B1 (de) * 1989-03-03 1994-07-27 Genentech, Inc. Methoden zur in vitro-dna-amplifikation, zum genomischen klonieren und zur genkartierung
US5219727A (en) * 1989-08-21 1993-06-15 Hoffmann-Laroche Inc. Quantitation of nucleic acids using the polymerase chain reaction
GB9016163D0 (en) * 1990-07-24 1990-09-05 Cemu Bioteknik Chemical method
AU657286B2 (en) * 1990-12-20 1995-03-09 F. Hoffmann-La Roche Ag PCR primers for detection of legionella species and methods for controlling visual intensity in hybridization assays
GB9116042D0 (en) * 1991-07-24 1991-09-11 Royal Free Hosp School Med Diagnostic method
DE69233285T2 (de) * 1991-08-02 2004-11-25 bioMérieux B.V. Quantifikation von Nukleinsäuren
US5457027A (en) * 1993-05-05 1995-10-10 Becton, Dickinson And Company Internal controls for isothermal nucleic acid amplification reactions

Also Published As

Publication number Publication date
CA2121658C (en) 1996-12-03
US5457027A (en) 1995-10-10
AU6058094A (en) 1994-11-10
US5840487A (en) 1998-11-24
EP0623682A1 (de) 1994-11-09
JP3127079B2 (ja) 2001-01-22
ES2136137T3 (es) 1999-11-16
EP0623682B1 (de) 1999-09-08
AU675503B2 (en) 1997-02-06
DE69420454D1 (de) 1999-10-14
SG50707A1 (en) 1998-07-20
JPH06343497A (ja) 1994-12-20
CA2121658A1 (en) 1994-11-06

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