DE69416522T2 - Iontophoretische verabreichung eines antimigränemittels - Google Patents

Iontophoretische verabreichung eines antimigränemittels

Info

Publication number
DE69416522T2
DE69416522T2 DE69416522T DE69416522T DE69416522T2 DE 69416522 T2 DE69416522 T2 DE 69416522T2 DE 69416522 T DE69416522 T DE 69416522T DE 69416522 T DE69416522 T DE 69416522T DE 69416522 T2 DE69416522 T2 DE 69416522T2
Authority
DE
Germany
Prior art keywords
formula
6alkyl
hydrogen
pct
bivalent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69416522T
Other languages
English (en)
Other versions
DE69416522D1 (de
Inventor
Jean Mesens
Reet Gustaaf Van
Beukelaar Frank De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of DE69416522D1 publication Critical patent/DE69416522D1/de
Application granted granted Critical
Publication of DE69416522T2 publication Critical patent/DE69416522T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69416522T 1993-08-27 1994-08-19 Iontophoretische verabreichung eines antimigränemittels Expired - Fee Related DE69416522T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP93202523 1993-08-27
PCT/EP1994/002764 WO1995005815A1 (en) 1993-08-27 1994-08-19 Iontophoretic delivery of an antimigraine drug

Publications (2)

Publication Number Publication Date
DE69416522D1 DE69416522D1 (de) 1999-03-25
DE69416522T2 true DE69416522T2 (de) 1999-09-23

Family

ID=8214068

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69416522T Expired - Fee Related DE69416522T2 (de) 1993-08-27 1994-08-19 Iontophoretische verabreichung eines antimigränemittels

Country Status (28)

Country Link
US (1) US5674871A (de)
EP (1) EP0719138B1 (de)
JP (1) JP2921987B2 (de)
KR (1) KR100187632B1 (de)
CN (1) CN1096857C (de)
AT (1) ATE176591T1 (de)
AU (1) AU687876B2 (de)
BR (1) BR9407522A (de)
CA (1) CA2168449A1 (de)
CZ (1) CZ290473B6 (de)
DE (1) DE69416522T2 (de)
DK (1) DK0719138T3 (de)
ES (1) ES2129668T3 (de)
FI (1) FI960887A (de)
GR (1) GR3029920T3 (de)
HR (1) HRP940481A2 (de)
HU (1) HUT75062A (de)
IL (1) IL110784A (de)
MY (1) MY111022A (de)
NO (1) NO317628B1 (de)
NZ (1) NZ273304A (de)
PH (1) PH31437A (de)
PL (1) PL176290B1 (de)
RU (1) RU2166315C2 (de)
SG (1) SG50469A1 (de)
SI (1) SI9400333B (de)
WO (1) WO1995005815A1 (de)
ZA (1) ZA946533B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5853383A (en) * 1995-05-03 1998-12-29 Alza Corporation Preparation for formulations for electrotransport drug delivery
US7137975B2 (en) * 2001-02-13 2006-11-21 Aciont, Inc. Method for increasing the battery life of an alternating current iontophoresis device using a barrier-modifying agent
MXPA03009121A (es) * 2001-04-04 2004-11-22 Johnson & Johnson Dispositivo de suministro de electrotransporte transdermico que incluye una composicion de reserva compatible antimicrobiana.
WO2002089803A1 (en) * 2001-05-07 2002-11-14 Sankyo Company, Limited Composition for iontophoresis
US8016811B2 (en) * 2003-10-24 2011-09-13 Altea Therapeutics Corporation Method for transdermal delivery of permeant substances
US20050220439A1 (en) * 2004-03-19 2005-10-06 Carton Owen A Interactive multimedia system and method
WO2007009462A2 (en) * 2005-07-15 2007-01-25 Region Hovedstaden V/Glostrup Hospital Treatment of migraine and headaches
CN101472644B (zh) * 2006-04-13 2014-04-23 纽帕特公司 递送抗偏头痛化合物的透皮方法和系统

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991015260A1 (en) * 1990-03-30 1991-10-17 Alza Corporation Device and method for iontophoretic drug delivery
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines

Also Published As

Publication number Publication date
CZ290473B6 (cs) 2002-07-17
AU687876B2 (en) 1998-03-05
US5674871A (en) 1997-10-07
PH31437A (en) 1998-11-03
WO1995005815A1 (en) 1995-03-02
KR100187632B1 (ko) 1999-06-01
HRP940481A2 (en) 1997-08-31
NO317628B1 (no) 2004-11-29
ATE176591T1 (de) 1999-02-15
JPH09501180A (ja) 1997-02-04
CN1096857C (zh) 2002-12-25
IL110784A0 (en) 1994-11-11
HU9600471D0 (en) 1996-04-29
EP0719138B1 (de) 1999-02-10
SI9400333A (en) 1995-04-30
HUT75062A (en) 1997-03-28
CZ57096A3 (en) 1996-08-14
DE69416522D1 (de) 1999-03-25
NZ273304A (en) 1997-02-24
ES2129668T3 (es) 1999-06-16
PL176290B1 (pl) 1999-05-31
EP0719138A1 (de) 1996-07-03
MY111022A (en) 1999-07-31
FI960887A0 (fi) 1996-02-26
FI960887A (fi) 1996-02-26
IL110784A (en) 1999-05-09
BR9407522A (pt) 1997-01-07
NO960769D0 (no) 1996-02-26
JP2921987B2 (ja) 1999-07-19
ZA946533B (en) 1996-02-26
SI9400333B (sl) 2002-02-28
AU7654294A (en) 1995-03-21
CN1129905A (zh) 1996-08-28
GR3029920T3 (en) 1999-07-30
SG50469A1 (en) 1998-07-20
RU2166315C2 (ru) 2001-05-10
DK0719138T3 (da) 1999-09-20
PL313255A1 (en) 1996-06-24
NO960769L (no) 1996-04-23
CA2168449A1 (en) 1995-03-02

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee