DE69415990T2 - Heterodimere der wachstumsfaktoren - Google Patents

Heterodimere der wachstumsfaktoren

Info

Publication number
DE69415990T2
DE69415990T2 DE69415990T DE69415990T DE69415990T2 DE 69415990 T2 DE69415990 T2 DE 69415990T2 DE 69415990 T DE69415990 T DE 69415990T DE 69415990 T DE69415990 T DE 69415990T DE 69415990 T2 DE69415990 T2 DE 69415990T2
Authority
DE
Germany
Prior art keywords
heterodimers
growth factors
neurotrophins
reassociation
homodimeric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69415990T
Other languages
English (en)
Other versions
DE69415990D1 (de
Inventor
Czeslaw Radziejewski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Regeneron Pharmaceuticals Inc
Original Assignee
Regeneron Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regeneron Pharmaceuticals Inc filed Critical Regeneron Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69415990D1 publication Critical patent/DE69415990D1/de
Publication of DE69415990T2 publication Critical patent/DE69415990T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69415990T 1993-10-18 1994-10-14 Heterodimere der wachstumsfaktoren Expired - Fee Related DE69415990T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13895193A 1993-10-18 1993-10-18
PCT/US1994/011696 WO1995011258A1 (en) 1993-10-18 1994-10-14 Growth factor heterodimers

Publications (2)

Publication Number Publication Date
DE69415990D1 DE69415990D1 (de) 1999-02-25
DE69415990T2 true DE69415990T2 (de) 1999-09-16

Family

ID=22484403

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69415990T Expired - Fee Related DE69415990T2 (de) 1993-10-18 1994-10-14 Heterodimere der wachstumsfaktoren

Country Status (7)

Country Link
EP (1) EP0724598B1 (de)
AT (1) ATE175677T1 (de)
AU (1) AU8017894A (de)
DE (1) DE69415990T2 (de)
IL (1) IL111323A0 (de)
WO (1) WO1995011258A1 (de)
ZA (1) ZA948167B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901428D0 (sv) * 1999-04-21 1999-04-21 Karolinska Innovations Ab Amphibodies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1232157B (it) * 1989-07-20 1992-01-25 Fidia Farmaceutici Purificazione del fattore di crescita nervoso tramite cromatografia a scambio di subunita'
US5235043A (en) * 1990-04-06 1993-08-10 Synergen, Inc. Production of biologically active, recombinant members of the ngf/bdnf family of neurotrophic proteins
US5349055A (en) * 1992-03-06 1994-09-20 Persson Hakan B Nerve growth factor having altered receptor binding specificities

Also Published As

Publication number Publication date
WO1995011258A1 (en) 1995-04-27
EP0724598B1 (de) 1999-01-13
AU8017894A (en) 1995-05-08
EP0724598A1 (de) 1996-08-07
ATE175677T1 (de) 1999-01-15
ZA948167B (en) 1995-06-08
IL111323A0 (en) 1994-12-29
DE69415990D1 (de) 1999-02-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee