DE69414586T2 - Verfahren zur herstellung von indolizinderivaten - Google Patents

Verfahren zur herstellung von indolizinderivaten

Info

Publication number
DE69414586T2
DE69414586T2 DE69414586T DE69414586T DE69414586T2 DE 69414586 T2 DE69414586 T2 DE 69414586T2 DE 69414586 T DE69414586 T DE 69414586T DE 69414586 T DE69414586 T DE 69414586T DE 69414586 T2 DE69414586 T2 DE 69414586T2
Authority
DE
Germany
Prior art keywords
producing
pct
indolicine
derivatives
date
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69414586T
Other languages
English (en)
Other versions
DE69414586D1 (de
Inventor
Satoshi Okada
Kozo Sawada
Akio Kuroda
Shinya Watanabe
Hirokazu Tanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE69414586D1 publication Critical patent/DE69414586D1/de
Application granted granted Critical
Publication of DE69414586T2 publication Critical patent/DE69414586T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
DE69414586T 1993-09-10 1994-09-06 Verfahren zur herstellung von indolizinderivaten Expired - Fee Related DE69414586T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939318790A GB9318790D0 (en) 1993-09-10 1993-09-10 Heterocyclic derivatives
PCT/JP1994/001465 WO1995007279A2 (en) 1993-09-10 1994-09-06 Process for the preparation of indolizine derivatives

Publications (2)

Publication Number Publication Date
DE69414586D1 DE69414586D1 (de) 1998-12-17
DE69414586T2 true DE69414586T2 (de) 1999-04-29

Family

ID=10741816

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69414586T Expired - Fee Related DE69414586T2 (de) 1993-09-10 1994-09-06 Verfahren zur herstellung von indolizinderivaten

Country Status (12)

Country Link
US (1) US5780633A (de)
EP (1) EP0717742B1 (de)
JP (1) JP3160909B2 (de)
KR (1) KR100339068B1 (de)
CN (1) CN1043992C (de)
AT (1) ATE173259T1 (de)
CA (1) CA2171308A1 (de)
DE (1) DE69414586T2 (de)
ES (1) ES2127937T3 (de)
GB (1) GB9318790D0 (de)
HU (1) HU216156B (de)
WO (1) WO1995007279A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU736668B2 (en) * 1996-10-01 2001-08-02 Glycodesign Inc. Novel 3, 5, and/or 6 substituted analogues of swainsonine, processes for their preparation and their use as therapeutic agents
US6395745B1 (en) 1997-04-15 2002-05-28 Glycodesign, Inc. Alkaloid halide salts of swainsonine and methods of use
EP1023290A1 (de) * 1997-10-24 2000-08-02 Glycodesign Inc. Synthese von swainsoninsalzen
FR2838123B1 (fr) * 2002-04-04 2005-06-10 Sanofi Synthelabo Nouveaux derives d'indolozine-1,2,3 substituee, inhibiteurs selectifs du b-fgf
WO2006050007A2 (en) 2004-11-01 2006-05-11 Wyeth Substituted indolizines and derivatives as cns agents

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334716A (en) * 1991-06-17 1994-08-02 Fujisawa Pharmaceutical Co., Ltd. Heterocyclic derivatives

Also Published As

Publication number Publication date
HU9600606D0 (en) 1996-05-28
CN1130907A (zh) 1996-09-11
HUT74290A (en) 1996-11-28
DE69414586D1 (de) 1998-12-17
CN1043992C (zh) 1999-07-07
KR960704889A (ko) 1996-10-09
GB9318790D0 (en) 1993-10-27
KR100339068B1 (ko) 2002-11-23
CA2171308A1 (en) 1995-03-16
JP3160909B2 (ja) 2001-04-25
EP0717742A1 (de) 1996-06-26
ES2127937T3 (es) 1999-05-01
US5780633A (en) 1998-07-14
ATE173259T1 (de) 1998-11-15
JPH09502200A (ja) 1997-03-04
EP0717742B1 (de) 1998-11-11
WO1995007279A3 (en) 1995-04-27
HU216156B (hu) 1999-04-28
WO1995007279A2 (en) 1995-03-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee