DE69412146D1 - Asymetrische "hammerhead" ribozyme und nukleotidsequenzen zu deren aufbau - Google Patents
Asymetrische "hammerhead" ribozyme und nukleotidsequenzen zu deren aufbauInfo
- Publication number
- DE69412146D1 DE69412146D1 DE69412146T DE69412146T DE69412146D1 DE 69412146 D1 DE69412146 D1 DE 69412146D1 DE 69412146 T DE69412146 T DE 69412146T DE 69412146 T DE69412146 T DE 69412146T DE 69412146 D1 DE69412146 D1 DE 69412146D1
- Authority
- DE
- Germany
- Prior art keywords
- ribozyms
- asymetric
- hammerhead
- nucleotide sequences
- nucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/111—Antisense spanning the whole gene, or a large part of it
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/121—Hammerhead
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP1993/002853 WO1995010608A1 (en) | 1993-10-15 | 1993-10-15 | Asymmetric hammerhead ribozymes and nucleotide sequences for their construction |
PCT/EP1994/003391 WO1995010609A1 (en) | 1993-10-15 | 1994-10-14 | Asymmetric hammerhead ribozymes and nucleotide sequences for their construction |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69412146D1 true DE69412146D1 (de) | 1998-09-03 |
DE69412146T2 DE69412146T2 (de) | 1999-04-29 |
Family
ID=8165777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69412146T Expired - Fee Related DE69412146T2 (de) | 1993-10-15 | 1994-10-14 | Asymetrische "hammerhead" ribozyme und nukleotidsequenzen zu deren aufbau |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0785998B1 (de) |
AU (2) | AU5334294A (de) |
DE (1) | DE69412146T2 (de) |
WO (2) | WO1995010608A1 (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000509969A (ja) * | 1996-04-02 | 2000-08-08 | コモンウェルス・サイエンティフィック・アンド・インダストリアル・リサーチ・オーガニゼーション | 非対称ハンマーヘッド型リボザイム |
CA2374388C (en) * | 2002-02-28 | 2005-07-12 | Matthew C. Coffey | The use of ribozymes in the detection of adventitious agents |
US20040005546A1 (en) | 2002-02-28 | 2004-01-08 | Oncolytics Biotech Inc. | Use of ribozymes in the detection of adventitious agents |
US8012747B2 (en) * | 2004-06-01 | 2011-09-06 | San Diego State University Foundation | Expression system |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE115999T1 (de) * | 1987-12-15 | 1995-01-15 | Gene Shears Pty Ltd | Ribozyme. |
CA2084790C (en) * | 1990-06-19 | 2002-04-09 | Philip Anthony Jennings | Endonucleases |
EP0558490A1 (de) * | 1990-07-26 | 1993-09-08 | FOUNDATION FOR RESEARCH AND TECHNOLOGY HELLAS (FO.R.T.H.) INSTITUTE OF MOLECULAR BIOLOGY & BIOTECHNOLOGY | Tragbare ribozyme-kassetten, diese kodierende dna-sequenzen, dadurch kodierte ribozyme und diese enthaltende mitteln |
-
1993
- 1993-10-15 AU AU53342/94A patent/AU5334294A/en not_active Abandoned
- 1993-10-15 WO PCT/EP1993/002853 patent/WO1995010608A1/en active Application Filing
-
1994
- 1994-10-14 EP EP94930172A patent/EP0785998B1/de not_active Expired - Lifetime
- 1994-10-14 DE DE69412146T patent/DE69412146T2/de not_active Expired - Fee Related
- 1994-10-14 WO PCT/EP1994/003391 patent/WO1995010609A1/en active IP Right Grant
- 1994-10-14 AU AU79378/94A patent/AU7937894A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU5334294A (en) | 1995-05-04 |
EP0785998A1 (de) | 1997-07-30 |
WO1995010609A1 (en) | 1995-04-20 |
AU7937894A (en) | 1995-05-04 |
EP0785998B1 (de) | 1998-07-29 |
WO1995010608A1 (en) | 1995-04-20 |
DE69412146T2 (de) | 1999-04-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |