DE69332910T2 - Ausgabevorrichtung - Google Patents
Ausgabevorrichtung Download PDFInfo
- Publication number
- DE69332910T2 DE69332910T2 DE69332910T DE69332910T DE69332910T2 DE 69332910 T2 DE69332910 T2 DE 69332910T2 DE 69332910 T DE69332910 T DE 69332910T DE 69332910 T DE69332910 T DE 69332910T DE 69332910 T2 DE69332910 T2 DE 69332910T2
- Authority
- DE
- Germany
- Prior art keywords
- atomization
- electrical
- electrode
- discharge
- atomized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000007788 liquid Substances 0.000 claims abstract description 61
- 150000002500 ions Chemical class 0.000 claims abstract description 31
- 230000005684 electric field Effects 0.000 claims abstract description 16
- 238000000889 atomisation Methods 0.000 claims description 60
- 239000000126 substance Substances 0.000 claims description 24
- 230000006698 induction Effects 0.000 claims description 20
- 239000003990 capacitor Substances 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 15
- 239000003814 drug Substances 0.000 claims description 10
- 229940079593 drug Drugs 0.000 claims description 9
- 230000004044 response Effects 0.000 claims description 7
- 239000000796 flavoring agent Substances 0.000 claims description 3
- 235000019634 flavors Nutrition 0.000 claims description 3
- 230000001939 inductive effect Effects 0.000 claims description 3
- 238000009688 liquid atomisation Methods 0.000 claims description 3
- 238000010521 absorption reaction Methods 0.000 claims description 2
- 239000002304 perfume Substances 0.000 claims description 2
- 238000004544 sputter deposition Methods 0.000 claims description 2
- 239000007921 spray Substances 0.000 abstract description 27
- 238000007599 discharging Methods 0.000 abstract 3
- 238000009472 formulation Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000001556 precipitation Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000029058 respiratory gaseous exchange Effects 0.000 description 4
- 239000002537 cosmetic Substances 0.000 description 3
- 210000002445 nipple Anatomy 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 230000015556 catabolic process Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 208000000884 Airway Obstruction Diseases 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 206010039163 Right ventricular failure Diseases 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 239000003139 biocide Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000004020 conductor Substances 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004070 electrodeposition Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000007667 floating Methods 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000003116 impacting effect Effects 0.000 description 1
- 238000002664 inhalation therapy Methods 0.000 description 1
- 239000000976 ink Substances 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- FJQXCDYVZAHXNS-UHFFFAOYSA-N methadone hydrochloride Chemical compound Cl.C=1C=CC=CC=1C(CC(C)N(C)C)(C(=O)CC)C1=CC=CC=C1 FJQXCDYVZAHXNS-UHFFFAOYSA-N 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 239000004081 narcotic agent Substances 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 239000006199 nebulizer Substances 0.000 description 1
- 230000003472 neutralizing effect Effects 0.000 description 1
- 239000000820 nonprescription drug Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
- 230000005180 public health Effects 0.000 description 1
- 208000002815 pulmonary hypertension Diseases 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000011877 solvent mixture Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 239000000273 veterinary drug Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/002—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
- B05B5/043—Discharge apparatus, e.g. electrostatic spray guns using induction-charging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
- B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Electrostatic Spraying Apparatus (AREA)
- Sampling And Sample Adjustment (AREA)
- Formation And Processing Of Food Products (AREA)
- Encapsulation Of And Coatings For Semiconductor Or Solid State Devices (AREA)
- Medicinal Preparation (AREA)
- Massaging Devices (AREA)
- Surgical Instruments (AREA)
- Electrostatic Charge, Transfer And Separation In Electrography (AREA)
- Wet Developing In Electrophotography (AREA)
- Catching Or Destruction (AREA)
- Cyclones (AREA)
- Noodles (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929226717A GB9226717D0 (en) | 1992-12-22 | 1992-12-22 | Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories |
| GB9226717 | 1992-12-22 | ||
| PCT/GB1993/002634 WO1994014543A2 (en) | 1992-12-22 | 1993-12-22 | Dispensing device |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69332910D1 DE69332910D1 (de) | 2003-05-28 |
| DE69332910T2 true DE69332910T2 (de) | 2004-05-19 |
Family
ID=10727028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69332910T Expired - Lifetime DE69332910T2 (de) | 1992-12-22 | 1993-12-22 | Ausgabevorrichtung |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP0675764B1 (enExample) |
| JP (1) | JPH08504670A (enExample) |
| KR (1) | KR100317897B1 (enExample) |
| CN (1) | CN1069557C (enExample) |
| AT (1) | ATE238105T1 (enExample) |
| AU (1) | AU716733B2 (enExample) |
| CA (1) | CA2152391C (enExample) |
| DE (1) | DE69332910T2 (enExample) |
| DK (1) | DK0675764T3 (enExample) |
| ES (1) | ES2196021T3 (enExample) |
| GB (1) | GB9226717D0 (enExample) |
| NZ (1) | NZ258988A (enExample) |
| PT (1) | PT675764E (enExample) |
| TW (1) | TW281641B (enExample) |
| WO (1) | WO1994014543A2 (enExample) |
| ZA (1) | ZA939614B (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9225098D0 (en) | 1992-12-01 | 1993-01-20 | Coffee Ronald A | Charged droplet spray mixer |
| US6105571A (en) | 1992-12-22 | 2000-08-22 | Electrosols, Ltd. | Dispensing device |
| GB9511514D0 (en) * | 1995-06-07 | 1995-08-02 | Ici Plc | Electrostatic spraying |
| SE504458C2 (sv) * | 1995-06-21 | 1997-02-17 | Lars Gunnar Nilsson | Inhalator för elektrisk dosering av substanser |
| US6079634A (en) * | 1996-05-30 | 2000-06-27 | The Procter & Gamble Company | Electrostatic spraying |
| US20080119772A1 (en) | 2001-01-11 | 2008-05-22 | Ronald Alan Coffee | Dispensing device and method for forming material |
| US6252129B1 (en) | 1996-07-23 | 2001-06-26 | Electrosols, Ltd. | Dispensing device and method for forming material |
| EP0912251B1 (en) | 1996-07-23 | 2004-04-07 | Battelle Memorial Institute | A dispensing device and method for forming material |
| US6350609B1 (en) * | 1997-06-20 | 2002-02-26 | New York University | Electrospraying for mass fabrication of chips and libraries |
| GB2327895B (en) * | 1997-08-08 | 2001-08-08 | Electrosols Ltd | A dispensing device |
| GB2334461B (en) | 1998-02-20 | 2002-01-23 | Bespak Plc | Inhalation apparatus |
| FR2776538B1 (fr) * | 1998-03-27 | 2000-07-21 | Centre Nat Rech Scient | Moyens de pulverisation electrohydrodynamique |
| CN1084225C (zh) * | 1998-04-24 | 2002-05-08 | 杭州大学 | 直接合成二甲醚的催化剂及其制备方法 |
| GB2345010B (en) * | 1998-12-17 | 2002-12-31 | Electrosols Ltd | A delivery device |
| US6397838B1 (en) * | 1998-12-23 | 2002-06-04 | Battelle Pulmonary Therapeutics, Inc. | Pulmonary aerosol delivery device and method |
| ATE274955T1 (de) | 1999-05-03 | 2004-09-15 | Battelle Memorial Institute | Arzneizusammensetzungen zur aerosolbildung und zu inhalationszwecken |
| CN1431919A (zh) | 2000-04-03 | 2003-07-23 | 巴特勒记忆研究所 | 装置和制剂 |
| US6339107B1 (en) | 2000-08-02 | 2002-01-15 | Syntex (U.S.A.) Llc | Methods for treatment of Emphysema using 13-cis retinoic acid |
| EP1935869A1 (en) | 2000-10-02 | 2008-06-25 | F. Hoffmann-La Roche Ag | Retinoids for the treatment of emphysema |
| JP2004526674A (ja) | 2000-12-01 | 2004-09-02 | バテル・メモリアル・インスティテュート | 液体処方物中における生体分子の安定化のための方法 |
| JP2005501810A (ja) | 2001-03-22 | 2005-01-20 | バテル メモリアル インスティチュート | ポリマーおよび懸濁粒子を含有する電気流体力学的噴霧用の液体形成物 |
| ZA200504940B (en) | 2003-01-28 | 2006-09-27 | Xenoport Inc | Amino acid derived prodrugs of propofol, compositions and uses thereof |
| JP4713465B2 (ja) | 2003-03-12 | 2011-06-29 | セルジーン コーポレイション | ７−アミド−イソインドリル化合物およびその薬学的使用 |
| PT3345895T (pt) | 2003-04-11 | 2020-01-29 | Ptc Therapeutics Inc | Composto de ácido 1,2,4-oxadiazole benzóico e a sua utilização para a supressão sem sentido e tratamento de doenças |
| US7230003B2 (en) | 2003-09-09 | 2007-06-12 | Xenoport, Inc. | Aromatic prodrugs of propofol, compositions and uses thereof |
| JP2007511618A (ja) | 2003-11-19 | 2007-05-10 | シグナル ファーマシューティカルズ，エルエルシー | インダゾール化合物およびタンパク質キナーゼ阻害剤としてのその使用方法 |
| DE602005010270D1 (de) | 2004-07-12 | 2008-11-20 | Xenoport Inc | Von aminosäuren abgeleitete prodrugs von propofolzusammensetzungen und anwendungen davon |
| US7241807B2 (en) | 2004-07-12 | 2007-07-10 | Xenoport, Inc. | Prodrugs of propofol, compositions and uses thereof |
| ES2525567T3 (es) | 2004-12-17 | 2014-12-26 | Anadys Pharmaceuticals, Inc. | Compuestos de 3H-oxazolo y 3H-tiazolo[4,5-d]pirimidin-2-ona 3,5-disustituidos y 3,5,7-trisustituidos y profármacos de los mismos |
| US7619110B2 (en) | 2004-12-23 | 2009-11-17 | Xenoport, Inc. | Amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof |
| EP1928881A2 (en) | 2005-08-19 | 2008-06-11 | Pharmacofore, Inc. | Prodrugs of active agents |
| JP2009530390A (ja) | 2006-03-23 | 2009-08-27 | アムゲン インコーポレイティッド | １−フェニルスルホニル−ジアザ複素環アミド化合物およびヒドロキシステロイドデヒドロゲナーゼ調節因子としてのその使用 |
| DK2046393T3 (da) | 2006-05-26 | 2014-05-12 | Signature Therapeutics Inc | Kontrolleret frigivelse af phenol-opioider |
| WO2007145834A2 (en) | 2006-06-08 | 2007-12-21 | Amgen Inc. | Benzamide derivatives and uses related thereto |
| TW200808695A (en) | 2006-06-08 | 2008-02-16 | Amgen Inc | Benzamide derivatives and uses related thereto |
| TWI395749B (zh) | 2006-06-22 | 2013-05-11 | Anadys Pharmaceuticals Inc | 吡咯并〔１，２-ｂ〕嗒酮化合物 |
| WO2007150002A2 (en) | 2006-06-22 | 2007-12-27 | Anadys Pharmaceuticals, Inc. | PRODRUGS OF 5-AMINO-3-(3'-DEOXY-β-D-RIBOFURANOSYL)-THIAZOLO[4,5-d] PYRIMIDIN-2,7-DIONE |
| EP2040712B1 (en) | 2006-07-18 | 2011-03-02 | Anadys Pharmaceuticals, Inc. | Carbonate and carbamate prodrugs of thiazolo [4,5-d] pyrimidines |
| CA2659155A1 (en) | 2006-07-20 | 2008-01-24 | Amgen Inc. | Substituted azole aromatic heterocycles as inhibitors of 11.beta.-hsd-1 |
| EP2121580A2 (en) | 2006-12-26 | 2009-11-25 | Amgen Inc. | N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases |
| ES2435799T3 (es) | 2008-10-09 | 2013-12-23 | Anadys Pharmaceuticals, Inc. | Un método de inhibición del virus de la hepatitis C mediante combinación de una 5,6-dihidro-1H-piridin-2-ona y de uno o más compuestos antivirales adicionales |
| US20120321590A1 (en) | 2011-04-06 | 2012-12-20 | Anadys Pharmaceuticals, Inc. | Bridged polycyclic compounds |
| US10335406B2 (en) | 2015-10-01 | 2019-07-02 | Elysium Therapeutics, Inc. | Opioid compositions resistant to overdose and abuse |
| AU2016332071B2 (en) | 2015-10-01 | 2019-04-18 | Elysium Therapeutics, Inc. | Polysubunit opioid prodrugs resistant to overdose and abuse |
| JP6657505B2 (ja) * | 2015-11-09 | 2020-03-04 | アネスト岩田株式会社 | 静電噴霧装置及び静電噴霧方法 |
| EP3323455B1 (de) * | 2016-11-21 | 2021-08-11 | Aptar Radolfzell GmbH | Inhalationseinrichtung zum zwecke des inhalierens eines tröpfchennebels |
| CA3056239C (en) | 2017-03-17 | 2023-09-12 | Elysium Therapeutics, Inc. | Polysubunit opioid prodrugs resistant to overdose and abuse |
| CN112915347B (zh) * | 2021-01-21 | 2023-09-05 | 浙江大学医学院附属第一医院 | 一种可连接呼吸机的前列环素药液电极雾化装置 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3565070A (en) * | 1969-02-28 | 1971-02-23 | Riker Laboratories Inc | Inhalation actuable aerosol dispenser |
| GB1527592A (en) * | 1974-08-05 | 1978-10-04 | Ici Ltd | Wound dressing |
| US4266721A (en) * | 1979-09-17 | 1981-05-12 | Ppg Industries, Inc. | Spray application of coating compositions utilizing induction and corona charging means |
| DE3475694D1 (en) * | 1983-08-18 | 1989-01-26 | Ici Plc | Electrostatic spraying process and apparatus |
| GB8604328D0 (en) * | 1986-02-21 | 1986-03-26 | Ici Plc | Producing spray of droplets of liquid |
| GB8614566D0 (en) * | 1986-06-16 | 1986-07-23 | Ici Plc | Spraying |
| US5115971A (en) * | 1988-09-23 | 1992-05-26 | Battelle Memorial Institute | Nebulizer device |
| US5044564A (en) * | 1989-11-21 | 1991-09-03 | Sickles James E | Electrostatic spray gun |
-
1992
- 1992-12-22 GB GB929226717A patent/GB9226717D0/en active Pending
-
1993
- 1993-12-22 DK DK94902940T patent/DK0675764T3/da active
- 1993-12-22 ES ES94902940T patent/ES2196021T3/es not_active Expired - Lifetime
- 1993-12-22 ZA ZA939614A patent/ZA939614B/xx unknown
- 1993-12-22 EP EP94902940A patent/EP0675764B1/en not_active Expired - Lifetime
- 1993-12-22 EP EP03076100A patent/EP1342504A3/en not_active Withdrawn
- 1993-12-22 CA CA002152391A patent/CA2152391C/en not_active Expired - Fee Related
- 1993-12-22 WO PCT/GB1993/002634 patent/WO1994014543A2/en not_active Ceased
- 1993-12-22 CN CN93119960A patent/CN1069557C/zh not_active Expired - Fee Related
- 1993-12-22 JP JP6514958A patent/JPH08504670A/ja active Pending
- 1993-12-22 AT AT94902940T patent/ATE238105T1/de not_active IP Right Cessation
- 1993-12-22 PT PT94902940T patent/PT675764E/pt unknown
- 1993-12-22 DE DE69332910T patent/DE69332910T2/de not_active Expired - Lifetime
- 1993-12-22 NZ NZ258988A patent/NZ258988A/en unknown
- 1993-12-22 KR KR1019950702570A patent/KR100317897B1/ko not_active Expired - Fee Related
-
1994
- 1994-02-15 TW TW083101178A patent/TW281641B/zh active
-
1998
- 1998-04-07 AU AU60699/98A patent/AU716733B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| TW281641B (enExample) | 1996-07-21 |
| KR950704050A (ko) | 1995-11-17 |
| EP1342504A2 (en) | 2003-09-10 |
| EP1342504A3 (en) | 2004-03-03 |
| CA2152391C (en) | 2007-03-06 |
| ES2196021T3 (es) | 2003-12-16 |
| ATE238105T1 (de) | 2003-05-15 |
| AU5709894A (en) | 1994-07-19 |
| HK1012302A1 (en) | 1999-07-30 |
| ZA939614B (en) | 1995-01-31 |
| EP0675764A1 (en) | 1995-10-11 |
| KR100317897B1 (ko) | 2002-07-31 |
| NZ258988A (en) | 1998-01-26 |
| AU6069998A (en) | 1998-06-11 |
| GB9226717D0 (en) | 1993-02-17 |
| EP0675764B1 (en) | 2003-04-23 |
| CN1090227A (zh) | 1994-08-03 |
| WO1994014543A3 (en) | 1994-09-15 |
| DK0675764T3 (da) | 2003-08-04 |
| WO1994014543A2 (en) | 1994-07-07 |
| AU684735B2 (en) | 1998-01-08 |
| JPH08504670A (ja) | 1996-05-21 |
| CA2152391A1 (en) | 1994-07-07 |
| CN1069557C (zh) | 2001-08-15 |
| DE69332910D1 (de) | 2003-05-28 |
| PT675764E (pt) | 2003-08-29 |
| AU716733B2 (en) | 2000-03-02 |
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