CN1069557C - 分配装置 - Google Patents

分配装置 Download PDF

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Publication number
CN1069557C
CN1069557C CN93119960A CN93119960A CN1069557C CN 1069557 C CN1069557 C CN 1069557C CN 93119960 A CN93119960 A CN 93119960A CN 93119960 A CN93119960 A CN 93119960A CN 1069557 C CN1069557 C CN 1069557C
Authority
CN
China
Prior art keywords
segmentation
electrode
inhaler
sparking electrode
valving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN93119960A
Other languages
English (en)
Chinese (zh)
Other versions
CN1090227A (zh
Inventor
R·A·科菲
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Memorial Institute Inc
Original Assignee
Electrosols Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Electrosols Ltd filed Critical Electrosols Ltd
Publication of CN1090227A publication Critical patent/CN1090227A/zh
Application granted granted Critical
Publication of CN1069557C publication Critical patent/CN1069557C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/002—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/043—Discharge apparatus, e.g. electrostatic spray guns using induction-charging

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrostatic Spraying Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Encapsulation Of And Coatings For Semiconductor Or Solid State Devices (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Medicinal Preparation (AREA)
  • Surgical Instruments (AREA)
  • Massaging Devices (AREA)
  • Electrostatic Charge, Transfer And Separation In Electrography (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Noodles (AREA)
  • Catching Or Destruction (AREA)
  • Wet Developing In Electrophotography (AREA)
  • Cyclones (AREA)
CN93119960A 1992-12-22 1993-12-22 分配装置 Expired - Fee Related CN1069557C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929226717A GB9226717D0 (en) 1992-12-22 1992-12-22 Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories
GB9226717.8 1992-12-22

Publications (2)

Publication Number Publication Date
CN1090227A CN1090227A (zh) 1994-08-03
CN1069557C true CN1069557C (zh) 2001-08-15

Family

ID=10727028

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93119960A Expired - Fee Related CN1069557C (zh) 1992-12-22 1993-12-22 分配装置

Country Status (16)

Country Link
EP (2) EP1342504A3 (enExample)
JP (1) JPH08504670A (enExample)
KR (1) KR100317897B1 (enExample)
CN (1) CN1069557C (enExample)
AT (1) ATE238105T1 (enExample)
AU (1) AU716733B2 (enExample)
CA (1) CA2152391C (enExample)
DE (1) DE69332910T2 (enExample)
DK (1) DK0675764T3 (enExample)
ES (1) ES2196021T3 (enExample)
GB (1) GB9226717D0 (enExample)
NZ (1) NZ258988A (enExample)
PT (1) PT675764E (enExample)
TW (1) TW281641B (enExample)
WO (1) WO1994014543A2 (enExample)
ZA (1) ZA939614B (enExample)

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GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
US6105571A (en) 1992-12-22 2000-08-22 Electrosols, Ltd. Dispensing device
GB9511514D0 (en) * 1995-06-07 1995-08-02 Ici Plc Electrostatic spraying
SE504458C2 (sv) * 1995-06-21 1997-02-17 Lars Gunnar Nilsson Inhalator för elektrisk dosering av substanser
US6079634A (en) * 1996-05-30 2000-06-27 The Procter & Gamble Company Electrostatic spraying
US20080119772A1 (en) 2001-01-11 2008-05-22 Ronald Alan Coffee Dispensing device and method for forming material
EP1388371B1 (en) 1996-07-23 2009-10-28 Battelle Memorial Institute A dispensing device and method for forming material
US6252129B1 (en) 1996-07-23 2001-06-26 Electrosols, Ltd. Dispensing device and method for forming material
CA2294449A1 (en) * 1997-06-20 1998-12-30 New York University Electrospraying solutions of substances for mass fabrication of chips and libraries
GB2327895B (en) * 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device
GB2334461B (en) * 1998-02-20 2002-01-23 Bespak Plc Inhalation apparatus
FR2776538B1 (fr) * 1998-03-27 2000-07-21 Centre Nat Rech Scient Moyens de pulverisation electrohydrodynamique
CN1084225C (zh) * 1998-04-24 2002-05-08 杭州大学 直接合成二甲醚的催化剂及其制备方法
GB2345010B (en) * 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US6397838B1 (en) * 1998-12-23 2002-06-04 Battelle Pulmonary Therapeutics, Inc. Pulmonary aerosol delivery device and method
WO2000066206A2 (en) 1999-05-03 2000-11-09 Battelle Memorial Institute Compositions for aerosolization and inhalation
CN1431919A (zh) 2000-04-03 2003-07-23 巴特勒记忆研究所 装置和制剂
US6339107B1 (en) 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid
EP1935869A1 (en) 2000-10-02 2008-06-25 F. Hoffmann-La Roche Ag Retinoids for the treatment of emphysema
MXPA03004883A (es) 2000-12-01 2004-05-04 Battelle Memorial Institute Metodo para la estabilizacion de biomoleculas (por ejemplo, insulina) en formulaciones liquidas.
JP2005501810A (ja) 2001-03-22 2005-01-20 バテル メモリアル インスティチュート ポリマーおよび懸濁粒子を含有する電気流体力学的噴霧用の液体形成物
ZA200504940B (en) 2003-01-28 2006-09-27 Xenoport Inc Amino acid derived prodrugs of propofol, compositions and uses thereof
WO2004080423A2 (en) 2003-03-12 2004-09-23 Celgene Corporation 7-amino- isoindolyl compounds amd their pharmaceutical uses
JP4851933B2 (ja) 2003-04-11 2012-01-11 ピーティーシー セラピューティクス，インコーポレーテッド １，２，４−オキサジアゾール安息香酸化合物ならびにナンセンス抑制及び疾患の治療のためのその使用
US7230003B2 (en) 2003-09-09 2007-06-12 Xenoport, Inc. Aromatic prodrugs of propofol, compositions and uses thereof
NZ547689A (en) 2003-11-19 2009-05-31 Signal Pharm Llc Indazole compounds and methods of use thereof as protein kinase inhibitors
US7241807B2 (en) 2004-07-12 2007-07-10 Xenoport, Inc. Prodrugs of propofol, compositions and uses thereof
PL1781596T3 (pl) 2004-07-12 2009-04-30 Xenoport Inc Aminokwasowe pochodne prekursory leków związku propofolu i ich zastosowanie
NZ555723A (en) 2004-12-17 2010-07-30 Anadys Pharmaceuticals Inc 3,5-disubstituted and 3,5,7-trisubstituted-3H-oxazolo and 3H-thiazolo[4,5-d]pyrimidin-2-one compounds and prodrugs thereof
ES2340189T3 (es) 2004-12-23 2010-05-31 Xenoport, Inc. Profarmacos de propofol derivados del aminoacido serina, composiciones, usos y formas cristalinas de los mismos.
US8163701B2 (en) 2005-08-19 2012-04-24 Signature Therapeutics, Inc. Prodrugs of active agents
CA2645487A1 (en) 2006-03-23 2007-10-04 Amgen Inc. 1-phenylsulfonyl-diaza heterocyclic amide compounds and their uses as modulators of hydroxsteroid dehydrogenases
MX2008014794A (es) 2006-05-26 2009-04-08 Pharmacofore Inc Liberacion controlada de opioides fenolicos.
TW200808695A (en) 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
EP2029540B1 (en) 2006-06-08 2010-08-04 Amgen Inc. Benzamide derivatives and uses related thereto
KR101384266B1 (ko) 2006-06-22 2014-04-24 애나디스 파마슈티칼스, 인코포레이티드 파이로［1,2-ｂ］파이리다지논 화합물
DE602007012247D1 (de) 2006-06-22 2011-03-10 Anadys Pharmaceuticals Inc Prodrugs von 5-amino-3-(3'-deoxy-beta-d-ribofuranosyl)-thiazolä4,5-düpyrimidin-2,7-dion
DE602007012881D1 (en) 2006-07-18 2011-04-14 Anadys Pharmaceuticals Inc Carbonat- und carbamat-prodrugs von thiazolo ä4,5-dü-pyrimidinen
WO2008011453A2 (en) 2006-07-20 2008-01-24 Amgen Inc. SUBSTITUTED AZOLE AROMATIC HETEROCYCLES AS INHIBITORS OF LLβ-HSD-1
EP2121580A2 (en) 2006-12-26 2009-11-25 Amgen Inc. N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
EP2346329B1 (en) 2008-10-09 2013-08-21 Anadys Pharmaceuticals, Inc. A method of inhibiting hepatitis c virus by combination of a 5,6-dihydro-1h-pyridin-2-one and one or more additional antiviral compounds
WO2012158271A1 (en) 2011-04-06 2012-11-22 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds as antiviral agents
WO2017059459A1 (en) 2015-10-01 2017-04-06 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
JP6657505B2 (ja) * 2015-11-09 2020-03-04 アネスト岩田株式会社 静電噴霧装置及び静電噴霧方法
EP3323455B1 (de) * 2016-11-21 2021-08-11 Aptar Radolfzell GmbH Inhalationseinrichtung zum zwecke des inhalierens eines tröpfchennebels
WO2018170465A1 (en) 2017-03-17 2018-09-20 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
CN112915347B (zh) * 2021-01-21 2023-09-05 浙江大学医学院附属第一医院 一种可连接呼吸机的前列环素药液电极雾化装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565070A (en) * 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
WO1991007232A1 (en) * 1989-11-21 1991-05-30 Sickles James E Electrostatic spray gun

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1527592A (en) * 1974-08-05 1978-10-04 Ici Ltd Wound dressing
US4266721A (en) * 1979-09-17 1981-05-12 Ppg Industries, Inc. Spray application of coating compositions utilizing induction and corona charging means
NZ209210A (en) * 1983-08-18 1988-04-29 Ici Plc Electrostatic sprayhead atomises aqueous liquids
GB8604328D0 (en) * 1986-02-21 1986-03-26 Ici Plc Producing spray of droplets of liquid
GB8614566D0 (en) * 1986-06-16 1986-07-23 Ici Plc Spraying
US5115971A (en) * 1988-09-23 1992-05-26 Battelle Memorial Institute Nebulizer device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565070A (en) * 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
WO1991007232A1 (en) * 1989-11-21 1991-05-30 Sickles James E Electrostatic spray gun

Also Published As

Publication number Publication date
AU5709894A (en) 1994-07-19
DE69332910T2 (de) 2004-05-19
ATE238105T1 (de) 2003-05-15
TW281641B (enExample) 1996-07-21
AU684735B2 (en) 1998-01-08
AU716733B2 (en) 2000-03-02
PT675764E (pt) 2003-08-29
CA2152391A1 (en) 1994-07-07
EP0675764A1 (en) 1995-10-11
WO1994014543A2 (en) 1994-07-07
HK1012302A1 (en) 1999-07-30
EP1342504A2 (en) 2003-09-10
WO1994014543A3 (en) 1994-09-15
KR100317897B1 (ko) 2002-07-31
CN1090227A (zh) 1994-08-03
NZ258988A (en) 1998-01-26
DK0675764T3 (da) 2003-08-04
CA2152391C (en) 2007-03-06
AU6069998A (en) 1998-06-11
ZA939614B (en) 1995-01-31
GB9226717D0 (en) 1993-02-17
JPH08504670A (ja) 1996-05-21
DE69332910D1 (de) 2003-05-28
ES2196021T3 (es) 2003-12-16
EP1342504A3 (en) 2004-03-03
EP0675764B1 (en) 2003-04-23
KR950704050A (ko) 1995-11-17

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: BATTELLE MEMORIAL INSTITUTE

Free format text: FORMER OWNER: ELECTROSOLS LTD.

Effective date: 20030307

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20030307

Address after: 505 Kings Road, Ohio, Columbo, USA

Patentee after: Battelle Memorial Inst.

Address before: England

Patentee before: Electrosols Ltd.

C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee