CN1069557C - 分配装置 - Google Patents

分配装置 Download PDF

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Publication number
CN1069557C
CN1069557C CN93119960A CN93119960A CN1069557C CN 1069557 C CN1069557 C CN 1069557C CN 93119960 A CN93119960 A CN 93119960A CN 93119960 A CN93119960 A CN 93119960A CN 1069557 C CN1069557 C CN 1069557C
Authority
CN
China
Prior art keywords
segmentation
electrode
inhaler
sparking electrode
valving
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN93119960A
Other languages
English (en)
Chinese (zh)
Other versions
CN1090227A (zh
Inventor
R·A·科菲
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Battelle Memorial Institute Inc
Original Assignee
Electrosols Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Electrosols Ltd filed Critical Electrosols Ltd
Publication of CN1090227A publication Critical patent/CN1090227A/zh
Application granted granted Critical
Publication of CN1069557C publication Critical patent/CN1069557C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/002—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means comprising means for neutralising the spray of charged droplets or particules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0091—Inhalators mechanically breath-triggered
    • A61M15/0093—Inhalators mechanically breath-triggered without arming or cocking, e.g. acting directly on the delivery valve
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/02—Inhalators with activated or ionised fluids, e.g. electrohydrodynamic [EHD] or electrostatic devices; Ozone-inhalators with radioactive tagged particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/0255—Discharge apparatus, e.g. electrostatic spray guns spraying and depositing by electrostatic forces only
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
    • B05B5/025—Discharge apparatus, e.g. electrostatic spray guns
    • B05B5/043—Discharge apparatus, e.g. electrostatic spray guns using induction-charging

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Electrostatic Spraying Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Encapsulation Of And Coatings For Semiconductor Or Solid State Devices (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Medicinal Preparation (AREA)
  • Electrostatic Charge, Transfer And Separation In Electrography (AREA)
  • Massaging Devices (AREA)
  • Surgical Instruments (AREA)
  • Noodles (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Wet Developing In Electrophotography (AREA)
  • Cyclones (AREA)
  • Catching Or Destruction (AREA)
CN93119960A 1992-12-22 1993-12-22 分配装置 Expired - Fee Related CN1069557C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929226717A GB9226717D0 (en) 1992-12-22 1992-12-22 Induction-operated electro-hydrodynamic spray device with means of modifying droplet trajectories
GB9226717.8 1992-12-22

Publications (2)

Publication Number Publication Date
CN1090227A CN1090227A (zh) 1994-08-03
CN1069557C true CN1069557C (zh) 2001-08-15

Family

ID=10727028

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93119960A Expired - Fee Related CN1069557C (zh) 1992-12-22 1993-12-22 分配装置

Country Status (16)

Country Link
EP (2) EP0675764B1 (enExample)
JP (1) JPH08504670A (enExample)
KR (1) KR100317897B1 (enExample)
CN (1) CN1069557C (enExample)
AT (1) ATE238105T1 (enExample)
AU (1) AU716733B2 (enExample)
CA (1) CA2152391C (enExample)
DE (1) DE69332910T2 (enExample)
DK (1) DK0675764T3 (enExample)
ES (1) ES2196021T3 (enExample)
GB (1) GB9226717D0 (enExample)
NZ (1) NZ258988A (enExample)
PT (1) PT675764E (enExample)
TW (1) TW281641B (enExample)
WO (1) WO1994014543A2 (enExample)
ZA (1) ZA939614B (enExample)

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GB9225098D0 (en) 1992-12-01 1993-01-20 Coffee Ronald A Charged droplet spray mixer
US6105571A (en) 1992-12-22 2000-08-22 Electrosols, Ltd. Dispensing device
GB9511514D0 (en) * 1995-06-07 1995-08-02 Ici Plc Electrostatic spraying
SE504458C2 (sv) * 1995-06-21 1997-02-17 Lars Gunnar Nilsson Inhalator för elektrisk dosering av substanser
US6079634A (en) * 1996-05-30 2000-06-27 The Procter & Gamble Company Electrostatic spraying
JP4077035B2 (ja) 1996-07-23 2008-04-16 バテル メモリアル インスティチュート 材料を形成する方法
US20080119772A1 (en) 2001-01-11 2008-05-22 Ronald Alan Coffee Dispensing device and method for forming material
US6252129B1 (en) 1996-07-23 2001-06-26 Electrosols, Ltd. Dispensing device and method for forming material
DE69841614D1 (de) * 1997-06-20 2010-05-27 Univ New York Elektrosprühen von lösungen zur massenherstellung von chips und molekülbibliotheken
GB2327895B (en) * 1997-08-08 2001-08-08 Electrosols Ltd A dispensing device
GB2334461B (en) * 1998-02-20 2002-01-23 Bespak Plc Inhalation apparatus
FR2776538B1 (fr) * 1998-03-27 2000-07-21 Centre Nat Rech Scient Moyens de pulverisation electrohydrodynamique
CN1084225C (zh) * 1998-04-24 2002-05-08 杭州大学 直接合成二甲醚的催化剂及其制备方法
GB2345010B (en) * 1998-12-17 2002-12-31 Electrosols Ltd A delivery device
US6397838B1 (en) * 1998-12-23 2002-06-04 Battelle Pulmonary Therapeutics, Inc. Pulmonary aerosol delivery device and method
DE60013425T2 (de) 1999-05-03 2005-09-08 Battelle Memorial Institute, Columbus Arzneizusammensetzungen zur aerosolbildung und zu inhalationszwecken
CA2405169C (en) 2000-04-03 2011-07-26 Battelle Memorial Institute Devices and formulations
US6339107B1 (en) 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid
EP1935869A1 (en) 2000-10-02 2008-06-25 F. Hoffmann-La Roche Ag Retinoids for the treatment of emphysema
EP1343521A2 (en) 2000-12-01 2003-09-17 Battelle Memorial Institute Method for the stabilizing biomolecules (e.g. insulin) in liquid formulations
US7891578B2 (en) 2001-03-22 2011-02-22 Battelle Memorial Institute Liquid formations for electrohydrodymanic spraying containing polymer and suspended particles
ZA200504940B (en) 2003-01-28 2006-09-27 Xenoport Inc Amino acid derived prodrugs of propofol, compositions and uses thereof
ES2436606T3 (es) 2003-03-12 2014-01-03 Celgene Corporation Compuestos de 7-amido-isoindolilo y sus usos farmacéuticos
HUE031794T2 (en) 2003-04-11 2017-08-28 Ptc Therapeutics Inc 1,2,4-oxadiol-benzoic acid compounds and their use for nonsense suppression and disease treatment
US7230003B2 (en) 2003-09-09 2007-06-12 Xenoport, Inc. Aromatic prodrugs of propofol, compositions and uses thereof
JP2007511618A (ja) 2003-11-19 2007-05-10 シグナル ファーマシューティカルズ，エルエルシー インダゾール化合物およびタンパク質キナーゼ阻害剤としてのその使用方法
ES2315897T3 (es) 2004-07-12 2009-04-01 Xenoport, Inc. Aminoacidos derivados de porfarmacos de composiciones de propofol y usos del mismo.
US7241807B2 (en) 2004-07-12 2007-07-10 Xenoport, Inc. Prodrugs of propofol, compositions and uses thereof
PT1824482E (pt) 2004-12-17 2014-05-13 Anadys Pharmaceuticals Inc Compostos 3h-oxazolo e 3h-tiazolo[4,5-d]pirimidin-2-ona 3,5- -di-substituídos e 3,5,7-tri-substituídos e seus pró- -fármacos
ES2340189T3 (es) 2004-12-23 2010-05-31 Xenoport, Inc. Profarmacos de propofol derivados del aminoacido serina, composiciones, usos y formas cristalinas de los mismos.
EP1928881A2 (en) 2005-08-19 2008-06-11 Pharmacofore, Inc. Prodrugs of active agents
EP2004619A1 (en) 2006-03-23 2008-12-24 Amgen Inc. 1-phenylsulfonyl-diaza heterocyclic amide compounds and their uses as modulators of hydroxsteroid dehydrogenases
CA2653741C (en) 2006-05-26 2015-07-07 Thomas E. Jenkins Controlled release of phenolic opioids
ES2349887T3 (es) 2006-06-08 2011-01-12 Amgen Inc. Derivados de benzamida y usos relacionados con los mismos.
TW200808695A (en) 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
WO2007150001A1 (en) 2006-06-22 2007-12-27 Anadys Pharmaceuticals, Inc. Pyrro[1,2-b]pyridazinone compounds
JP5345527B2 (ja) 2006-06-22 2013-11-20 アナディス ファーマシューティカルズ インク プロドラッグである５−アミノ−３−（３’−デオキシ−β−Ｄ−リボフラノシル）−チアゾロ［４，５−ｄ］ピリミジン−２，７−ジオン
EP2040712B1 (en) 2006-07-18 2011-03-02 Anadys Pharmaceuticals, Inc. Carbonate and carbamate prodrugs of thiazolo [4,5-d] pyrimidines
CA2659155A1 (en) 2006-07-20 2008-01-24 Amgen Inc. Substituted azole aromatic heterocycles as inhibitors of 11.beta.-hsd-1
AU2007343726A1 (en) 2006-12-26 2008-07-24 Amgen Inc. N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
US20110229438A1 (en) 2008-10-09 2011-09-22 Anadys Pharmaceuticals, Inc. Method of inhibiting hepatitus c virus by combination of a 5,6-dihydro-1h-pyridin-2-one and one or more additional antiviral compounds
WO2012158271A1 (en) 2011-04-06 2012-11-22 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds as antiviral agents
GB2556817B (en) 2015-10-01 2019-11-06 Elysium Therapeutics Inc Polysubunit opioid prodrugs resistant to overdose and abuse
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
JP6657505B2 (ja) * 2015-11-09 2020-03-04 アネスト岩田株式会社 静電噴霧装置及び静電噴霧方法
EP3323455B1 (de) * 2016-11-21 2021-08-11 Aptar Radolfzell GmbH Inhalationseinrichtung zum zwecke des inhalierens eines tröpfchennebels
WO2018170465A1 (en) 2017-03-17 2018-09-20 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
CN112915347B (zh) * 2021-01-21 2023-09-05 浙江大学医学院附属第一医院 一种可连接呼吸机的前列环素药液电极雾化装置

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565070A (en) * 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
WO1991007232A1 (en) * 1989-11-21 1991-05-30 Sickles James E Electrostatic spray gun

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1527592A (en) * 1974-08-05 1978-10-04 Ici Ltd Wound dressing
US4266721A (en) * 1979-09-17 1981-05-12 Ppg Industries, Inc. Spray application of coating compositions utilizing induction and corona charging means
EP0152446B1 (en) * 1983-08-18 1988-12-21 Imperial Chemical Industries Plc Electrostatic spraying process and apparatus
GB8604328D0 (en) * 1986-02-21 1986-03-26 Ici Plc Producing spray of droplets of liquid
GB8614566D0 (en) * 1986-06-16 1986-07-23 Ici Plc Spraying
US5115971A (en) * 1988-09-23 1992-05-26 Battelle Memorial Institute Nebulizer device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3565070A (en) * 1969-02-28 1971-02-23 Riker Laboratories Inc Inhalation actuable aerosol dispenser
WO1991007232A1 (en) * 1989-11-21 1991-05-30 Sickles James E Electrostatic spray gun

Also Published As

Publication number Publication date
EP0675764B1 (en) 2003-04-23
AU6069998A (en) 1998-06-11
WO1994014543A3 (en) 1994-09-15
KR100317897B1 (ko) 2002-07-31
CN1090227A (zh) 1994-08-03
JPH08504670A (ja) 1996-05-21
PT675764E (pt) 2003-08-29
AU716733B2 (en) 2000-03-02
AU5709894A (en) 1994-07-19
WO1994014543A2 (en) 1994-07-07
KR950704050A (ko) 1995-11-17
GB9226717D0 (en) 1993-02-17
EP0675764A1 (en) 1995-10-11
HK1012302A1 (en) 1999-07-30
CA2152391C (en) 2007-03-06
AU684735B2 (en) 1998-01-08
EP1342504A3 (en) 2004-03-03
EP1342504A2 (en) 2003-09-10
ES2196021T3 (es) 2003-12-16
NZ258988A (en) 1998-01-26
DE69332910T2 (de) 2004-05-19
ZA939614B (en) 1995-01-31
ATE238105T1 (de) 2003-05-15
DE69332910D1 (de) 2003-05-28
TW281641B (enExample) 1996-07-21
DK0675764T3 (da) 2003-08-04
CA2152391A1 (en) 1994-07-07

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: BATTELLE MEMORIAL INSTITUTE

Free format text: FORMER OWNER: ELECTROSOLS LTD.

Effective date: 20030307

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20030307

Address after: 505 Kings Road, Ohio, Columbo, USA

Patentee after: Battelle Memorial Inst.

Address before: England

Patentee before: Electrosols Ltd.

C19 Lapse of patent right due to non-payment of the annual fee
CF01 Termination of patent right due to non-payment of annual fee