DE69332576D1 - Glykolisierte Cytokine - Google Patents

Glykolisierte Cytokine

Info

Publication number
DE69332576D1
DE69332576D1 DE69332576T DE69332576T DE69332576D1 DE 69332576 D1 DE69332576 D1 DE 69332576D1 DE 69332576 T DE69332576 T DE 69332576T DE 69332576 T DE69332576 T DE 69332576T DE 69332576 D1 DE69332576 D1 DE 69332576D1
Authority
DE
Germany
Prior art keywords
glycolized
cytokines
cytokine
liver
sugar
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69332576T
Other languages
English (en)
Other versions
DE69332576T2 (de
Inventor
Naoru Hamaguchi
Jun Sato
Kazuhiro Doken
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69332576D1 publication Critical patent/DE69332576D1/de
Publication of DE69332576T2 publication Critical patent/DE69332576T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
DE69332576T 1992-09-24 1993-09-18 Glykolisierte Cytokine Expired - Fee Related DE69332576T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP25496292 1992-09-24
JP8892093 1993-04-15

Publications (2)

Publication Number Publication Date
DE69332576D1 true DE69332576D1 (de) 2003-01-30
DE69332576T2 DE69332576T2 (de) 2003-11-20

Family

ID=26430256

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332576T Expired - Fee Related DE69332576T2 (de) 1992-09-24 1993-09-18 Glykolisierte Cytokine

Country Status (9)

Country Link
US (1) US5643564A (de)
EP (1) EP0589378B1 (de)
KR (1) KR940007058A (de)
CN (1) CN1087916A (de)
AT (1) ATE229981T1 (de)
CA (1) CA2106821A1 (de)
DE (1) DE69332576T2 (de)
PH (1) PH31582A (de)
TW (1) TW263437B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0770195A (ja) * 1993-08-23 1995-03-14 Yutaka Mizushima 糖修飾インターフェロン
IL116730A0 (en) * 1995-01-13 1996-05-14 Amgen Inc Chemically modified interferon
JP3104257B2 (ja) * 1995-08-30 2000-10-30 東レ株式会社 心疾患治療剤
AUPP660698A0 (en) * 1998-10-21 1998-11-12 University Of Queensland, The A method of protein engineering
AR078117A1 (es) 2006-06-20 2011-10-19 Protech Pharma S A Una muteina recombinante del interferon alfa humano glicosilado, un gen que codifica para dicha muteina, un metodo de produccion de dicho gen, un metodo para obtener una celula eucariota productora de dicha muteina, un metodo para producir dicha muteina, un procedimiento para purificar dicha muteina
CN103429226A (zh) * 2011-03-02 2013-12-04 森苏林公司 囊泡组合物
AU2018300069A1 (en) 2017-07-11 2020-02-27 Synthorx, Inc. Incorporation of unnatural nucleotides and methods thereof
CA3071013A1 (en) 2017-08-03 2019-02-07 Synthorx, Inc. Cytokine conjugates for the treatment of proliferative and infectious diseases
BR112021014415A2 (pt) 2019-02-06 2021-09-21 Synthorx, Inc. Conjugados de il-2 e métodos de uso dos mesmos

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4386026A (en) * 1981-04-20 1983-05-31 Merck & Co., Inc. Cell-specific glycopeptide ligands
EP0098110B1 (de) * 1982-06-24 1989-10-18 NIHON CHEMICAL RESEARCH KABUSHIKI KAISHA also known as JAPAN CHEMICAL RESEARCH CO., LTD Zusammensetzung mit längerer Wirkung
JP2514950B2 (ja) * 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質，その製造法および中間体
JPS63152393A (ja) * 1986-07-03 1988-06-24 Takeda Chem Ind Ltd グリコシル誘導体
HU206890B (en) * 1986-10-13 1993-01-28 Sandoz Ag Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components
US5162503A (en) * 1987-05-19 1992-11-10 Hoffmann-La Roche, Inc. Purification of interleukin-2 by receptor-affinity chromatography
US4829690A (en) * 1987-06-26 1989-05-16 Andros Theodore A Credit card chain holder
JPH01102098A (ja) * 1987-10-14 1989-04-19 Toray Ind Inc 糖鎖修飾糖タンパク質
JPH01102099A (ja) * 1987-10-14 1989-04-19 Toray Ind Inc 生理活性を有する糖タンパク質
US4902502A (en) * 1989-01-23 1990-02-20 Cetus Corporation Preparation of a polymer/interleukin-2 conjugate
JPH03106900A (ja) * 1989-09-20 1991-05-07 Toray Ind Inc 糖鎖修飾ヒトインターフェロン集合体
JPH085914B2 (ja) * 1990-02-16 1996-01-24 株式会社ディ・ディ・エス研究所 グリコシル−蛋白誘導体
US5096816A (en) * 1990-06-05 1992-03-17 Cetus Corporation In vitro management of ammonia's effect on glycosylation of cell products through pH control
JPH0770195A (ja) * 1993-08-23 1995-03-14 Yutaka Mizushima 糖修飾インターフェロン

Also Published As

Publication number Publication date
US5643564A (en) 1997-07-01
EP0589378A2 (de) 1994-03-30
KR940007058A (ko) 1994-04-26
PH31582A (en) 1998-11-03
EP0589378A3 (de) 1995-02-22
CN1087916A (zh) 1994-06-15
DE69332576T2 (de) 2003-11-20
ATE229981T1 (de) 2003-01-15
EP0589378B1 (de) 2002-12-18
CA2106821A1 (en) 1994-03-25
TW263437B (de) 1995-11-21

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: TAKEDA PHARMACEUTICAL CO. LTD., OSAKA, JP

8339 Ceased/non-payment of the annual fee