DE69332267D1 - Bestimmung von bindungsaffinität mittels magnetisch markierter bindungspartner - Google Patents

Bestimmung von bindungsaffinität mittels magnetisch markierter bindungspartner

Info

Publication number
DE69332267D1
DE69332267D1 DE69332267T DE69332267T DE69332267D1 DE 69332267 D1 DE69332267 D1 DE 69332267D1 DE 69332267 T DE69332267 T DE 69332267T DE 69332267 T DE69332267 T DE 69332267T DE 69332267 D1 DE69332267 D1 DE 69332267D1
Authority
DE
Germany
Prior art keywords
binding
sffinity
determination
magnetically marked
binding partners
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69332267T
Other languages
English (en)
Inventor
E Rohr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69332267D1 publication Critical patent/DE69332267D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Compounds Of Iron (AREA)
  • Soft Magnetic Materials (AREA)
DE69332267T 1992-03-20 1993-03-15 Bestimmung von bindungsaffinität mittels magnetisch markierter bindungspartner Expired - Lifetime DE69332267D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85418692A 1992-03-20 1992-03-20
PCT/US1993/002337 WO1993019371A1 (en) 1992-03-20 1993-03-15 Determination of binding affinity using magneticaly-labeled binding members

Publications (1)

Publication Number Publication Date
DE69332267D1 true DE69332267D1 (de) 2002-10-10

Family

ID=25317969

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69332267T Expired - Lifetime DE69332267D1 (de) 1992-03-20 1993-03-15 Bestimmung von bindungsaffinität mittels magnetisch markierter bindungspartner

Country Status (7)

Country Link
EP (1) EP0631668B1 (de)
JP (1) JP2625578B2 (de)
AU (1) AU661140B2 (de)
CA (1) CA2129044C (de)
DE (1) DE69332267D1 (de)
TW (1) TW247347B (de)
WO (1) WO1993019371A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993019370A1 (en) * 1992-03-20 1993-09-30 Abbott Laboratories Magnetically assisted binding assays using magnetically-labeled binding members
US5998224A (en) * 1997-05-16 1999-12-07 Abbott Laboratories Magnetically assisted binding assays utilizing a magnetically responsive reagent
EP1198712A2 (de) * 1999-02-17 2002-04-24 Kilian Hennes Verfahren zum darstellen von biologisch aktivierten induktivitätsändernden partikeln sowie vorrichtung dafür
US6294342B1 (en) 1999-09-29 2001-09-25 Abbott Laboratories Magnetically assisted binding assays utilizing a magnetically responsive reagent
AU2001293747A1 (en) * 2000-08-11 2002-02-25 Nanotype Gmbh Method and device for characterising and/or for detecting a bonding complex
DE10117866A1 (de) * 2001-04-10 2002-10-17 Nanotype Gmbh Verfahren und Vorrichtung zur Charakterisierung und/oder zum Nachweis eines Bindungskomplexes
DE10126798A1 (de) 2001-06-01 2002-12-19 Nanotype Gmbh Verfahren zur Bestimmung einer Probe
EP1651960A1 (de) * 2003-07-30 2006-05-03 Koninklijke Philips Electronics N.V. Verwendung von magnetpartikeln zur bestimmung der bindungsstärke von bioaktiven molekülen
US20060040273A1 (en) * 2004-08-17 2006-02-23 Alison Chaiken Method and apparatus for magnetic sensing and control of reagents
EP1801594A1 (de) * 2005-12-23 2007-06-27 Koninklijke Philips Electronics N.V. Messvorrichtung und Verfahren zur Bestimmung der Anzahl an Zielmolekülen in einem Analyt
JP7411219B2 (ja) * 2020-03-26 2024-01-11 国立研究開発法人産業技術総合研究所 磁場と重力を用いる標的物質検出装置及び標的物質検出方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0287665B1 (de) * 1986-09-22 1996-07-31 Nippon Telegraph And Telephone Corporation Lasermagnetisches immuntestverfahren und vorrichtung dazu
WO1993019370A1 (en) * 1992-03-20 1993-09-30 Abbott Laboratories Magnetically assisted binding assays using magnetically-labeled binding members

Also Published As

Publication number Publication date
CA2129044C (en) 1999-07-06
JPH07504987A (ja) 1995-06-01
EP0631668B1 (de) 2002-09-04
AU661140B2 (en) 1995-07-13
AU3808593A (en) 1993-10-21
WO1993019371A1 (en) 1993-09-30
EP0631668A1 (de) 1995-01-04
CA2129044A1 (en) 1993-09-30
EP0631668A4 (de) 1996-04-17
TW247347B (de) 1995-05-11
JP2625578B2 (ja) 1997-07-02

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Legal Events

Date Code Title Description
8332 No legal effect for de