DE69331786T2 - Eine representative behandlung der dns-analyse - Google Patents

Eine representative behandlung der dns-analyse

Info

Publication number
DE69331786T2
DE69331786T2 DE69331786T DE69331786T DE69331786T2 DE 69331786 T2 DE69331786 T2 DE 69331786T2 DE 69331786 T DE69331786 T DE 69331786T DE 69331786 T DE69331786 T DE 69331786T DE 69331786 T2 DE69331786 T2 DE 69331786T2
Authority
DE
Germany
Prior art keywords
dna analysis
representative treatment
representative
treatment
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69331786T
Other languages
English (en)
Other versions
DE69331786D1 (de
Inventor
Michael Wigler
Nikolai Lisitsyn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cold Spring Harbor Laboratory
Original Assignee
Cold Spring Harbor Laboratory
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cold Spring Harbor Laboratory filed Critical Cold Spring Harbor Laboratory
Publication of DE69331786D1 publication Critical patent/DE69331786D1/de
Application granted granted Critical
Publication of DE69331786T2 publication Critical patent/DE69331786T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • C12Q1/6855Ligating adaptors
DE69331786T 1992-11-12 1993-11-08 Eine representative behandlung der dns-analyse Expired - Fee Related DE69331786T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/974,447 US5436142A (en) 1992-11-12 1992-11-12 Methods for producing probes capable of distingushing variant genomic sequences
PCT/US1993/010722 WO1994011383A1 (en) 1992-11-12 1993-11-08 A representational approach to dna analysis

Publications (2)

Publication Number Publication Date
DE69331786D1 DE69331786D1 (de) 2002-05-08
DE69331786T2 true DE69331786T2 (de) 2002-11-28

Family

ID=25522047

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331786T Expired - Fee Related DE69331786T2 (de) 1992-11-12 1993-11-08 Eine representative behandlung der dns-analyse

Country Status (7)

Country Link
US (4) US5436142A (de)
EP (1) EP0733125B1 (de)
JP (1) JP3535159B2 (de)
CA (1) CA2149249A1 (de)
DE (1) DE69331786T2 (de)
DK (1) DK0733125T3 (de)
WO (1) WO1994011383A1 (de)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
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US6277606B1 (en) 1993-11-09 2001-08-21 Cold Spring Harbor Laboratory Representational approach to DNA analysis
US20040197774A1 (en) * 1992-11-12 2004-10-07 Michael Wigler Representational approach to DNA analysis
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ATE264922T1 (de) * 1995-12-22 2004-05-15 Exact Sciences Corp Verfahren zur erkennung von klonalen populationen von transformierten zellen in einer genomisch heterogenen zellulären probe
US6218119B1 (en) * 1996-01-16 2001-04-17 Keygene, N. V. Amplification of simple sequence repeats
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US5827658A (en) * 1996-08-09 1998-10-27 The United States Of America As Reprsented By The Department Of Health And Human Services Isolation of amplified genes via cDNA subtractive hybridization
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Also Published As

Publication number Publication date
DK0733125T3 (da) 2002-07-29
US5501964A (en) 1996-03-26
DE69331786D1 (de) 2002-05-08
JPH08503365A (ja) 1996-04-16
US6159713A (en) 2000-12-12
EP0733125A1 (de) 1996-09-25
US5876929A (en) 1999-03-02
EP0733125A4 (de) 1996-04-11
WO1994011383A1 (en) 1994-05-26
JP3535159B2 (ja) 2004-06-07
EP0733125B1 (de) 2002-04-03
US5436142A (en) 1995-07-25
CA2149249A1 (en) 1994-05-26

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