DE69331230T2 - VERWENDUNG VON rETINOESÄURE ZUR HERSTELLUNG EINES ARZNEIMITTELS ZUR BEHANDLUNG VON HYPERPIGMENTIERUNG BEI SCHWARZER HAUT UND VERFAHREN ZUM AUFHELLEN SCHWARZER HAUT MIT RETINOESÄURE - Google Patents

VERWENDUNG VON rETINOESÄURE ZUR HERSTELLUNG EINES ARZNEIMITTELS ZUR BEHANDLUNG VON HYPERPIGMENTIERUNG BEI SCHWARZER HAUT UND VERFAHREN ZUM AUFHELLEN SCHWARZER HAUT MIT RETINOESÄURE

Info

Publication number
DE69331230T2
DE69331230T2 DE69331230T DE69331230T DE69331230T2 DE 69331230 T2 DE69331230 T2 DE 69331230T2 DE 69331230 T DE69331230 T DE 69331230T DE 69331230 T DE69331230 T DE 69331230T DE 69331230 T2 DE69331230 T2 DE 69331230T2
Authority
DE
Germany
Prior art keywords
retinoic acid
black skin
lightening
producing
medicinal product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69331230T
Other languages
English (en)
Other versions
DE69331230D1 (de
Inventor
J Voorhees
N Ellis
E Griffiths
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan
Original Assignee
University of Michigan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Michigan filed Critical University of Michigan
Application granted granted Critical
Publication of DE69331230D1 publication Critical patent/DE69331230D1/de
Publication of DE69331230T2 publication Critical patent/DE69331230T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69331230T 1992-03-31 1993-03-31 VERWENDUNG VON rETINOESÄURE ZUR HERSTELLUNG EINES ARZNEIMITTELS ZUR BEHANDLUNG VON HYPERPIGMENTIERUNG BEI SCHWARZER HAUT UND VERFAHREN ZUM AUFHELLEN SCHWARZER HAUT MIT RETINOESÄURE Expired - Fee Related DE69331230T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/861,133 US5750570A (en) 1992-03-31 1992-03-31 Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid
PCT/US1993/002711 WO1993019743A1 (en) 1992-03-31 1993-03-31 Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid

Publications (2)

Publication Number Publication Date
DE69331230D1 DE69331230D1 (de) 2002-01-10
DE69331230T2 true DE69331230T2 (de) 2002-08-29

Family

ID=25334976

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331230T Expired - Fee Related DE69331230T2 (de) 1992-03-31 1993-03-31 VERWENDUNG VON rETINOESÄURE ZUR HERSTELLUNG EINES ARZNEIMITTELS ZUR BEHANDLUNG VON HYPERPIGMENTIERUNG BEI SCHWARZER HAUT UND VERFAHREN ZUM AUFHELLEN SCHWARZER HAUT MIT RETINOESÄURE

Country Status (8)

Country Link
US (2) US5750570A (de)
EP (1) EP0633773B1 (de)
AT (1) ATE209484T1 (de)
AU (1) AU3931993A (de)
DE (1) DE69331230T2 (de)
ES (1) ES2169041T3 (de)
SG (1) SG50440A1 (de)
WO (1) WO1993019743A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750570A (en) * 1992-03-31 1998-05-12 The Regents Of The University Of Michigan Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid
US5401517A (en) * 1993-11-15 1995-03-28 Elizabeth Arden Company, Division Of Conopco, Inc. Cosmetic method for treatment of skin
US5599548A (en) * 1995-05-08 1997-02-04 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing fatty acid amides and retinol or retinyl ester
US5536740A (en) * 1995-06-01 1996-07-16 Elizabeth Arden Company, Division Of Conopco, Inc. Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester
US6183774B1 (en) 1996-01-31 2001-02-06 Collaborative Laboratories, Inc. Stabilizing vitamin A derivatives by encapsulation in lipid vesicles formed with alkylammonium fatty acid salts
US5716627A (en) * 1996-04-25 1998-02-10 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester
US5693330A (en) * 1996-04-25 1997-12-02 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing melinamide and a retinoid
US5744148A (en) * 1996-09-20 1998-04-28 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Stabilization of an unstable retinoid in oil-in-water emulsions for skin care compositions
US5955092A (en) * 1996-09-27 1999-09-21 Elizabeth Arden Co., Division Of Conopco, Inc. Skin care compositions containing an n-substituted fatty acid amide and retinol or retinyl ester
US8541469B2 (en) * 1997-08-23 2013-09-24 Glaxo Group Limited Treatment of cell-mediated immune diseases
EP0908179A1 (de) * 1997-08-23 1999-04-14 Werner Bollag Behandlung von zellvermittelten Immunkrankheiten
GB9918022D0 (en) 1999-07-30 1999-09-29 Unilever Plc Skin care composition
AP2002002534A0 (en) * 1999-11-09 2002-06-30 Univ Michigan Regents A method of treating and lightening hyperpigmentation in black skin with a retinoid.
WO2001066080A1 (en) * 2000-03-07 2001-09-13 Avon Products, Inc. Methods using phytol to improve the appearance of skin and compositions for such methods
US20040043044A1 (en) 2000-06-30 2004-03-04 Granger Stewart Paton Skin conditioning compositions containing compounds for mimicking the effect on skin of retinoic acid
US20050154407A1 (en) * 2000-12-20 2005-07-14 Fox Hollow Technologies, Inc. Method of evaluating drug efficacy for treating atherosclerosis
US6949247B2 (en) 2000-12-28 2005-09-27 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Stable skin care compositions containing a retinoid and a retinoid booster system
US6565864B2 (en) 2000-12-28 2003-05-20 Unilever Home & Personal Care Usa, A Division Of Conopco, Inc. Skin care product containing retinoids and phytoestrogens in a dual compartment package
WO2004043469A1 (en) 2001-11-16 2004-05-27 Klysz Beatrice M Anti-aging skin care composition and uses thereof
US20030212077A1 (en) * 2002-05-08 2003-11-13 Birnbaum Jay E. Methods and compositions for treating tinea versicolor using combinations of retinoids and certain antifungals
JP2004020220A (ja) * 2002-06-12 2004-01-22 Pioneer Electronic Corp 通信システム及び方法、通信端末装置、通信センタ装置、並びにコンピュータプログラム
DE102004016250A1 (de) * 2004-04-02 2005-10-20 Merck Patent Gmbh Chromon-Komplexe
US7794413B2 (en) * 2005-04-19 2010-09-14 Ev3, Inc. Libraries and data structures of materials removed by debulking catheters
DE102007013366A1 (de) 2007-03-16 2008-09-18 Merck Patent Gmbh Verwendung von Chroman-4-on-Derivaten
EP1977743B1 (de) 2007-03-20 2009-09-02 Johnson & Johnson Consumer France SAS Zusammensetzung enthältend Retinoid und Beta-aminoisobuttersäurederivate
ES2327201B1 (es) 2008-04-23 2010-07-23 Ignacio Umbert Millet Composicion farmaceutica personalizada para el rejuvenecimiento de la piel que contiene acido retinoico.
DE102010054149A1 (de) 2010-12-10 2012-06-14 Merck Patent Gmbh 2-Pyrone
ES2378028B1 (es) 2012-02-22 2013-02-18 Ignacio Umbert Millet Composición cosmética para el rejuvenecimiento de la piel y procedimiento y usos correspondientes
FR3067933B1 (fr) * 2017-06-21 2020-07-17 L'oreal Modulateurs de l’opsine 3 dans la modulation de la pigmentation de la peau

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750570A (en) * 1992-03-31 1998-05-12 The Regents Of The University Of Michigan Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid
US5266307A (en) * 1992-03-31 1993-11-30 The Regents Of The University Of Michigan Retinoic acid as a skin tanning agent in persons of light skin color

Also Published As

Publication number Publication date
US5750570A (en) 1998-05-12
EP0633773B1 (de) 2001-11-28
DE69331230D1 (de) 2002-01-10
WO1993019743A1 (en) 1993-10-14
SG50440A1 (en) 1998-07-20
US6017960A (en) 2000-01-25
EP0633773A4 (de) 1994-11-09
AU3931993A (en) 1993-11-08
EP0633773A1 (de) 1995-01-18
ATE209484T1 (de) 2001-12-15
ES2169041T3 (es) 2002-07-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee