ES2169041T3 - Metodo para el tratamiento de la hiperpigmentacion en la piel negra con acido retinoico y metodo para aclarar la piel negra con acido retinoico. - Google Patents
Metodo para el tratamiento de la hiperpigmentacion en la piel negra con acido retinoico y metodo para aclarar la piel negra con acido retinoico.Info
- Publication number
- ES2169041T3 ES2169041T3 ES93908528T ES93908528T ES2169041T3 ES 2169041 T3 ES2169041 T3 ES 2169041T3 ES 93908528 T ES93908528 T ES 93908528T ES 93908528 T ES93908528 T ES 93908528T ES 2169041 T3 ES2169041 T3 ES 2169041T3
- Authority
- ES
- Spain
- Prior art keywords
- retinoic acid
- black skin
- treatment
- hyperpigmentation
- black
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 title 2
- 229930002330 retinoic acid Natural products 0.000 title 2
- 229960001727 tretinoin Drugs 0.000 title 2
- 208000000069 hyperpigmentation Diseases 0.000 title 1
- 230000003810 hyperpigmentation Effects 0.000 title 1
- 206010036229 Post inflammatory pigmentation change Diseases 0.000 abstract 3
- 230000035876 healing Effects 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 abstract 2
- 102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 abstract 1
- 108010015742 Cytochrome P-450 Enzyme System Proteins 0.000 abstract 1
- 239000007844 bleaching agent Substances 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 239000007854 depigmenting agent Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 150000004492 retinoid derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
LA HIPERPIGMENTACION DE LA PIEL NEGRA PUEDE TRATARSE MEDIANTE LA APLICACION TOPICA DE ACIDO RETINOICO A LA PIEL. LA APLICACION TOPICA DEL ACIDO RETINOICO TAMBIEN ES EFECTIVA PARA ACLARAR LA PIEL NEGRA NORMAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/861,133 US5750570A (en) | 1992-03-31 | 1992-03-31 | Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2169041T3 true ES2169041T3 (es) | 2002-07-01 |
Family
ID=25334976
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93908528T Expired - Lifetime ES2169041T3 (es) | 1992-03-31 | 1993-03-31 | Metodo para el tratamiento de la hiperpigmentacion en la piel negra con acido retinoico y metodo para aclarar la piel negra con acido retinoico. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5750570A (es) |
EP (1) | EP0633773B1 (es) |
AT (1) | ATE209484T1 (es) |
AU (1) | AU3931993A (es) |
DE (1) | DE69331230T2 (es) |
ES (1) | ES2169041T3 (es) |
SG (1) | SG50440A1 (es) |
WO (1) | WO1993019743A1 (es) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750570A (en) * | 1992-03-31 | 1998-05-12 | The Regents Of The University Of Michigan | Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid |
US5401517A (en) * | 1993-11-15 | 1995-03-28 | Elizabeth Arden Company, Division Of Conopco, Inc. | Cosmetic method for treatment of skin |
US5599548A (en) * | 1995-05-08 | 1997-02-04 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides and retinol or retinyl ester |
US5536740A (en) * | 1995-06-01 | 1996-07-16 | Elizabeth Arden Company, Division Of Conopco, Inc. | Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester |
US6183774B1 (en) | 1996-01-31 | 2001-02-06 | Collaborative Laboratories, Inc. | Stabilizing vitamin A derivatives by encapsulation in lipid vesicles formed with alkylammonium fatty acid salts |
US5716627A (en) * | 1996-04-25 | 1998-02-10 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester |
US5693330A (en) * | 1996-04-25 | 1997-12-02 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing melinamide and a retinoid |
US5744148A (en) * | 1996-09-20 | 1998-04-28 | Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. | Stabilization of an unstable retinoid in oil-in-water emulsions for skin care compositions |
US5955092A (en) * | 1996-09-27 | 1999-09-21 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing an n-substituted fatty acid amide and retinol or retinyl ester |
US8541469B2 (en) * | 1997-08-23 | 2013-09-24 | Glaxo Group Limited | Treatment of cell-mediated immune diseases |
EP0908179A1 (en) * | 1997-08-23 | 1999-04-14 | Werner Bollag | Treatment of cell-mediated immune diseases |
GB9918022D0 (en) | 1999-07-30 | 1999-09-29 | Unilever Plc | Skin care composition |
AP2002002534A0 (en) * | 1999-11-09 | 2002-06-30 | Univ Michigan Regents | A method of treating and lightening hyperpigmentation in black skin with a retinoid. |
WO2001066080A1 (en) * | 2000-03-07 | 2001-09-13 | Avon Products, Inc. | Methods using phytol to improve the appearance of skin and compositions for such methods |
US20040043044A1 (en) | 2000-06-30 | 2004-03-04 | Granger Stewart Paton | Skin conditioning compositions containing compounds for mimicking the effect on skin of retinoic acid |
US20050154407A1 (en) * | 2000-12-20 | 2005-07-14 | Fox Hollow Technologies, Inc. | Method of evaluating drug efficacy for treating atherosclerosis |
US6949247B2 (en) | 2000-12-28 | 2005-09-27 | Unilever Home & Personal Care Usa Division Of Conopco, Inc. | Stable skin care compositions containing a retinoid and a retinoid booster system |
US6565864B2 (en) | 2000-12-28 | 2003-05-20 | Unilever Home & Personal Care Usa, A Division Of Conopco, Inc. | Skin care product containing retinoids and phytoestrogens in a dual compartment package |
WO2004043469A1 (en) | 2001-11-16 | 2004-05-27 | Klysz Beatrice M | Anti-aging skin care composition and uses thereof |
US20030212077A1 (en) * | 2002-05-08 | 2003-11-13 | Birnbaum Jay E. | Methods and compositions for treating tinea versicolor using combinations of retinoids and certain antifungals |
JP2004020220A (ja) * | 2002-06-12 | 2004-01-22 | Pioneer Electronic Corp | 通信システム及び方法、通信端末装置、通信センタ装置、並びにコンピュータプログラム |
DE102004016250A1 (de) * | 2004-04-02 | 2005-10-20 | Merck Patent Gmbh | Chromon-Komplexe |
US7794413B2 (en) * | 2005-04-19 | 2010-09-14 | Ev3, Inc. | Libraries and data structures of materials removed by debulking catheters |
DE102007013366A1 (de) | 2007-03-16 | 2008-09-18 | Merck Patent Gmbh | Verwendung von Chroman-4-on-Derivaten |
EP1977743B1 (en) | 2007-03-20 | 2009-09-02 | Johnson & Johnson Consumer France SAS | Compositions containing retinoid and beta-aminoisobutyric acid derivates |
ES2327201B1 (es) | 2008-04-23 | 2010-07-23 | Ignacio Umbert Millet | Composicion farmaceutica personalizada para el rejuvenecimiento de la piel que contiene acido retinoico. |
DE102010054149A1 (de) | 2010-12-10 | 2012-06-14 | Merck Patent Gmbh | 2-Pyrone |
ES2378028B1 (es) | 2012-02-22 | 2013-02-18 | Ignacio Umbert Millet | Composición cosmética para el rejuvenecimiento de la piel y procedimiento y usos correspondientes |
FR3067933B1 (fr) * | 2017-06-21 | 2020-07-17 | L'oreal | Modulateurs de l’opsine 3 dans la modulation de la pigmentation de la peau |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5750570A (en) * | 1992-03-31 | 1998-05-12 | The Regents Of The University Of Michigan | Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid |
US5266307A (en) * | 1992-03-31 | 1993-11-30 | The Regents Of The University Of Michigan | Retinoic acid as a skin tanning agent in persons of light skin color |
-
1992
- 1992-03-31 US US07/861,133 patent/US5750570A/en not_active Expired - Fee Related
-
1993
- 1993-03-31 DE DE69331230T patent/DE69331230T2/de not_active Expired - Fee Related
- 1993-03-31 EP EP93908528A patent/EP0633773B1/en not_active Expired - Lifetime
- 1993-03-31 SG SG1996001514A patent/SG50440A1/en unknown
- 1993-03-31 AU AU39319/93A patent/AU3931993A/en not_active Abandoned
- 1993-03-31 AT AT93908528T patent/ATE209484T1/de active
- 1993-03-31 ES ES93908528T patent/ES2169041T3/es not_active Expired - Lifetime
- 1993-03-31 WO PCT/US1993/002711 patent/WO1993019743A1/en active IP Right Grant
-
1998
- 1998-05-12 US US09/076,355 patent/US6017960A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5750570A (en) | 1998-05-12 |
DE69331230T2 (de) | 2002-08-29 |
EP0633773B1 (en) | 2001-11-28 |
DE69331230D1 (de) | 2002-01-10 |
WO1993019743A1 (en) | 1993-10-14 |
SG50440A1 (en) | 1998-07-20 |
US6017960A (en) | 2000-01-25 |
EP0633773A4 (en) | 1994-11-09 |
AU3931993A (en) | 1993-11-08 |
EP0633773A1 (en) | 1995-01-18 |
ATE209484T1 (de) | 2001-12-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2169041T3 (es) | Metodo para el tratamiento de la hiperpigmentacion en la piel negra con acido retinoico y metodo para aclarar la piel negra con acido retinoico. | |
NZ331237A (en) | Superficial chemical skin peels using salicyclic acid | |
CO4900023A1 (es) | Composiciones cosmeticas substancialmente libres de compues- tos | |
HK59493A (en) | Dermatological,pharmaceutical or cosmetic composition consisting of hydrated lipid lamellar phases or liposomes and containing retinoids or analogues such as carotenoids | |
KR950031034A (ko) | 화장품 또는 피부과용 조성물 및 그의 제법 | |
MX9702920A (es) | Composiciones para el cuidado de la piel que contienen amidas de acido graso, azoles y retinol o ester retinilico. | |
CA2175581A1 (en) | Desquamation compositions containing salicylic acid and zwitterionic compounds | |
BR9803281A (pt) | Composição contendo hidróxi-ácido e reinóide; e; processo cosmético para reduzir picada ou irritação induzida pela aplicação local de uma composição contendo um hidróxi-ácido ou um retinóide. | |
ES2168334T3 (es) | Composicion para el tratamiento de la piel. | |
ES2167516T3 (es) | Composiciones para el cuidado de la piel que contienen dimetilimidazolidinona y retinol o ester de retinilo. | |
CY1107732T1 (el) | Συνθεση αποπηγμεντωσης για το δερμα περιλαμβανουσα αδαπαλενιο και ενα τουλαχιστον παραγοντα αποπηγμεντωσης | |
ES2166862T3 (es) | Composiciones para el cuidado de la piel que contienen amidas de acidos grasos y retinol o esteres de retinilo. | |
MY130044A (en) | Retinoid composition | |
AR009096A1 (es) | UNA COMPOSICIoN PARA EL CUIDADO DE LA PIEL QUE CONTIENE COMBINACIONES DE COMPUESTOS PARA IMITAR EL EFECTO EN LA PIEL DEL ACIDO RETINOICO Y METODOS COSMETICOS, NO TERAPEUTICOS, PARA EL ACONDICIONAMIENTO DE LA PIEL QUE COMPRENDEN LA APLICACIoN DE DICHA COMPOSICIoN Y LA IMITACIoN DEL EFECTO DEL ACIDO R | |
EP0803247A3 (en) | Skin care compositions containing a retinoid | |
CA2004861A1 (en) | Dermal uses of non-irritating retinoids | |
AU5132799A (en) | Short contact treatment of acne and photoaging with topical retinoids | |
AP2002002534A0 (en) | A method of treating and lightening hyperpigmentation in black skin with a retinoid. | |
Cotellessa et al. | Microabrasion versus microabrasion followed by 15% trichloroacetic acid for treatment of cutaneous hyperpigmentations in adult females | |
MX9804118A (es) | Tratamiento dermico con esteres de acido salicilico y compuestos retinoides. | |
HK1004888A1 (en) | Synergistic skin depigmentation composition | |
IL94914A0 (en) | Resolution of threo-3-((2-aminophenyl)thio)-2-hydroxy-3-(4-methoxyphenyl)propionic acid | |
Zimmer | Effects of low pH acclimation on cladocerans: Clues to the interaction of physiology and ecology of acid lake zooplankton. | |
JPS53113025A (en) | Proliferation inhibitor for microorganisms | |
JPS53133892A (en) | Auxiliary apparatus for emergency stopping of ship |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 633773 Country of ref document: ES |