DE69326559T2 - Rekombinante methode und wirt zur herstellung von xylitol - Google Patents

Rekombinante methode und wirt zur herstellung von xylitol

Info

Publication number
DE69326559T2
DE69326559T2 DE69326559T DE69326559T DE69326559T2 DE 69326559 T2 DE69326559 T2 DE 69326559T2 DE 69326559 T DE69326559 T DE 69326559T DE 69326559 T DE69326559 T DE 69326559T DE 69326559 T2 DE69326559 T2 DE 69326559T2
Authority
DE
Germany
Prior art keywords
xylitol
host
production
recombinant method
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69326559T
Other languages
German (de)
English (en)
Other versions
DE69326559D1 (de
Inventor
Anu Harkki
Andrey Myasnikov
Juha Apajalahti
Ossi Pastinen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xyrofin Oy
Original Assignee
Xyrofin Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xyrofin Oy filed Critical Xyrofin Oy
Application granted granted Critical
Publication of DE69326559D1 publication Critical patent/DE69326559D1/de
Publication of DE69326559T2 publication Critical patent/DE69326559T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1022—Transferases (2.) transferring aldehyde or ketonic groups (2.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69326559T 1992-11-05 1993-11-05 Rekombinante methode und wirt zur herstellung von xylitol Expired - Lifetime DE69326559T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97332592A 1992-11-05 1992-11-05
PCT/FI1993/000450 WO1994010325A1 (fr) 1992-11-05 1993-11-05 Production de xylitol par recombinaison et hote utilise pour ce procede

Publications (2)

Publication Number Publication Date
DE69326559D1 DE69326559D1 (de) 1999-10-28
DE69326559T2 true DE69326559T2 (de) 2000-02-10

Family

ID=25520759

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69326559T Expired - Lifetime DE69326559T2 (de) 1992-11-05 1993-11-05 Rekombinante methode und wirt zur herstellung von xylitol

Country Status (15)

Country Link
JP (1) JP3433295B2 (fr)
KR (1) KR950704503A (fr)
AT (1) ATE184917T1 (fr)
AU (1) AU5421594A (fr)
BR (1) BR9307391A (fr)
CA (1) CA2148622A1 (fr)
DE (1) DE69326559T2 (fr)
ES (1) ES2139024T3 (fr)
FI (1) FI108300B (fr)
HU (1) HU219016B (fr)
NO (1) NO951747L (fr)
NZ (1) NZ257561A (fr)
PL (1) PL178040B1 (fr)
RU (1) RU2142999C1 (fr)
WO (1) WO1994010325A1 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7226761B2 (en) 1992-11-05 2007-06-05 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
US6723540B1 (en) 1992-11-05 2004-04-20 Xyrofin Oy Manufacture of xylitol using recombinant microbial hosts
GB9514538D0 (en) * 1995-07-15 1995-09-13 Cerestar Holding Bv Process for the production of xylitol
FR2762011B1 (fr) * 1997-04-11 1999-06-25 Roquette Freres Procede de preparation de ribitol par voie fermentaire et souche de microorganismes mise en oeuvre dans ce procede
FR2765589B1 (fr) * 1997-07-03 1999-09-17 Roquette Freres Fragment d'adn comprenant le promoteur de la ribulose reductase nadph specifique de yamadazyma ohmeri, vecteur le contenant et procede de preparation de proteines utilisant ce vecteur
JPH11266888A (ja) * 1997-10-17 1999-10-05 Ajinomoto Co Inc キシリトールの製造法
JP3855486B2 (ja) * 1997-10-17 2006-12-13 味の素株式会社 キシリトールの製造法
US6335177B1 (en) 1998-07-08 2002-01-01 Ajinomoto Co., Inc. Microorganisms and method for producing xylitol or d-xylulose
PE20001023A1 (es) 1998-07-30 2000-10-10 Ajinomoto Kk Deshidrogenasa de xilitol de bacterias de acido acetico y su gen
NZ512088A (en) 1998-12-08 2004-01-30 Children S Hospital And Region Polymorphic loci that differentiate escherichia coli 0157:H7 from other strains
JP2000210095A (ja) 1999-01-20 2000-08-02 Ajinomoto Co Inc キシリト―ル又はｄ―キシルロ―スの製造法
JP2000295994A (ja) * 1999-02-09 2000-10-24 Ajinomoto Co Inc キシリトールの製造法
US6830903B1 (en) 1999-07-23 2004-12-14 Archer-Daniels-Midland Company Methods for producing L-amino acids using a corynebacterium glutamicum with a disrupted pgi gene
DE60030988T2 (de) 1999-07-23 2007-01-04 Archer Daniels Midland Co., Decatur Verfahren zur Herstellung Von L-Aminosäuren durch Erhöhung des zellulären NADPH
JP2003520583A (ja) * 2000-01-21 2003-07-08 ダニスコ スイートナーズ オイ 五炭糖及び糖アルコールの製造
US6894199B2 (en) 2001-04-27 2005-05-17 Danisco Sweeteners Oy Process for the production of xylitol
GB2406855A (en) * 2003-02-07 2005-04-13 Danisco Sweeteners Oy Production of xylitol from a carbon source other than xylose and xylulose
WO2005113759A2 (fr) * 2004-05-19 2005-12-01 Biotechnology Research And Development Corporation Fabrication microbienne de xylitol au moyen d'hexose phosphate et d'un produit intermediaire de pentose phosphate
WO2005113773A1 (fr) * 2004-05-20 2005-12-01 Warnex Research Inc. Polynucleotides servant a detecter les producteurs de verotoxine escherichia coli o157:h7 et escherichia coli o157:nm
KR101246780B1 (ko) * 2010-10-06 2013-03-26 한국과학기술원 아라비노스 대사경로가 도입된 자일리톨 생산균주 및 이를 이용한 자일리톨 생산방법
DK2957640T3 (en) * 2014-06-18 2018-06-25 Roquette Freres Preparation of xylitol from glucose by a recombinant strain
WO2023220547A1 (fr) * 2022-05-09 2023-11-16 Cargill, Incorporated Levure génétiquement modifiée et procédés de fermentation pour la production de polyoles

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4009676A1 (de) * 1990-03-26 1991-10-02 Rhein Biotech Proz & Prod Gmbh Dna-sequenz, umfassend ein fuer xylosereduktase und/oder xylitoldehydrogenase codierendes strukturgen
FI901771A (fi) * 1990-04-06 1991-10-07 Valtion Teknillinen Anvaendning av xylos hos hybridjaest.

Also Published As

Publication number Publication date
FI952148A (fi) 1995-07-04
NO951747D0 (no) 1995-05-04
KR950704503A (ko) 1995-11-20
RU2142999C1 (ru) 1999-12-20
NO951747L (no) 1995-07-05
FI952148A0 (fi) 1995-05-04
CA2148622A1 (fr) 1994-05-11
DE69326559D1 (de) 1999-10-28
JP3433295B2 (ja) 2003-08-04
HUT72187A (en) 1996-03-28
RU95113172A (ru) 1997-03-27
HU219016B (hu) 2001-01-29
PL178040B1 (pl) 2000-02-29
AU5421594A (en) 1994-05-24
JPH08505522A (ja) 1996-06-18
FI108300B (fi) 2001-12-31
WO1994010325A1 (fr) 1994-05-11
PL308742A1 (en) 1995-08-21
ES2139024T3 (es) 2000-02-01
ATE184917T1 (de) 1999-10-15
HU9501288D0 (en) 1995-06-28
NZ257561A (en) 1996-09-25
BR9307391A (pt) 1999-08-31

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Legal Events

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8327 Change in the person/name/address of the patent owner

Owner name: XYROFIN OY, ESPOO, FI

8364 No opposition during term of opposition