DE69324831T2 - Verfahren zum Reihentesten von Fungiziden unter Verwendung eines Dihydroorotat-Dehydrogenase-(DHOD)-Hemmtests - Google Patents

Verfahren zum Reihentesten von Fungiziden unter Verwendung eines Dihydroorotat-Dehydrogenase-(DHOD)-Hemmtests

Info

Publication number
DE69324831T2
DE69324831T2 DE69324831T DE69324831T DE69324831T2 DE 69324831 T2 DE69324831 T2 DE 69324831T2 DE 69324831 T DE69324831 T DE 69324831T DE 69324831 T DE69324831 T DE 69324831T DE 69324831 T2 DE69324831 T2 DE 69324831T2
Authority
DE
Germany
Prior art keywords
dhod
fungicides
inhibition test
dihydroorotate dehydrogenase
serial testing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69324831T
Other languages
English (en)
Other versions
DE69324831D1 (de
Inventor
George E Davis
Gary D Gustafson
Matthew J Henry
Amy J Smith
Clive Waldron
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corteva Agriscience LLC
Original Assignee
Dow AgroSciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow AgroSciences LLC filed Critical Dow AgroSciences LLC
Publication of DE69324831D1 publication Critical patent/DE69324831D1/de
Application granted granted Critical
Publication of DE69324831T2 publication Critical patent/DE69324831T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/32—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving dehydrogenase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/05—Oxidoreductases acting on the CH-CH group of donors (1.3) with a quinone or related compound as acceptor (1.3.5)
    • C12Y103/05002—Dihydroorotate dehydrogenase (1.3.5.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69324831T 1992-01-30 1993-01-26 Verfahren zum Reihentesten von Fungiziden unter Verwendung eines Dihydroorotat-Dehydrogenase-(DHOD)-Hemmtests Expired - Fee Related DE69324831T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/828,078 US5976848A (en) 1990-08-03 1992-01-30 Method of identifying potential fungicides using dihydroorotate dehydrogenase inhibition assay

Publications (2)

Publication Number Publication Date
DE69324831D1 DE69324831D1 (de) 1999-06-17
DE69324831T2 true DE69324831T2 (de) 1999-09-09

Family

ID=25250877

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69324831T Expired - Fee Related DE69324831T2 (de) 1992-01-30 1993-01-26 Verfahren zum Reihentesten von Fungiziden unter Verwendung eines Dihydroorotat-Dehydrogenase-(DHOD)-Hemmtests

Country Status (4)

Country Link
US (1) US5976848A (de)
EP (1) EP0554042B1 (de)
JP (1) JP3187585B2 (de)
DE (1) DE69324831T2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL125861A (en) * 1996-03-05 2001-12-23 Novartis Ag Test system for chemicals or chemical mixtures
JP2002512812A (ja) * 1998-04-24 2002-05-08 ヘキスト・マリオン・ルセル 抗真菌性物質のサッカロミセス・セレビシエ由来の必須遺伝子を用いるスクリーニング法
EP0972847A3 (de) * 1998-04-24 2000-02-09 Hoechst Marion Roussel Verfahren zur Detektion von Antimycotika
EP0999284A1 (de) * 1998-09-11 2000-05-10 Hoechst Marion Roussel Verfahren zum Screening auf Antimykotika unter Verwendung essentieller Gene aus C.albicans, sowie die Gene selbst
CA2416039A1 (en) * 2000-07-14 2002-01-24 Basf Aktiengesellschaft Method for detecting uracil biosynthesis inhibitors and their use as herbicides
US20030166201A1 (en) * 2001-04-30 2003-09-04 Jensen Michael C. Selection systems for genetically modified cells
US6723529B2 (en) 2001-11-09 2004-04-20 Paradigm Genetics, Inc. Methods for the identification of inhibitors of α-aminoadipate reductase as antibiotics
US6632631B1 (en) 2001-11-09 2003-10-14 Paradigm Genetics, Inc. Methods for the identification of inhibitors of homocitrate synthase as antibiotics
US6852484B2 (en) * 2001-12-10 2005-02-08 Icoria, Inc. Methods for the identification of inhibitors of asparagine synthase as antibiotics
US6733963B2 (en) 2001-12-06 2004-05-11 Paradigm Genetics, Inc. Methods for the identification of inhibitors of 3-isopropylmalate dehydratase as antibiotics
US6806060B2 (en) 2001-12-07 2004-10-19 Icoria, Inc. Methods for the identification of inhibitors of threonine synthase as antibiotics
US6689578B2 (en) 2001-12-06 2004-02-10 Paradigm Genetics, Inc. Methods for the identification of inhibitors of 5-aminolevulinate synthase as antibiotics
US6740498B2 (en) 2001-12-06 2004-05-25 Paradigm Genetics, Inc. Methods for the identification of inhibitors of histidinol-phosphate as antibiotics
DE10160660A1 (de) * 2001-12-11 2003-06-18 Bayer Cropscience Ag Polypeptide zum Identifizieren von fungizid wirksamen Verbindungen
US20030228645A1 (en) * 2002-05-16 2003-12-11 Sheryl Frank Methods for the identification of inhibitors of chitin synthase 2 as antibiotics
US20030224970A1 (en) * 2002-05-17 2003-12-04 Sanjoy Mahanty Methods for the identification of inhibitors of S-adenosylmethionine decarboxylase as antibiotics
US20030228650A1 (en) * 2002-05-17 2003-12-11 Amy Skalchunes Methods for the identification of inhibitors of Methylenetetrahydrofolate reductase as antibiotics
DE10235129A1 (de) * 2002-08-01 2004-02-19 Bayer Cropscience Ag Verfahren zum Identifizieren von Fungiziden
GB0808029D0 (en) * 2008-05-01 2008-06-11 F2G Ltd Antifungal target
US8686048B2 (en) 2010-05-06 2014-04-01 Rhizen Pharmaceuticals Sa Immunomodulator and anti-inflammatory compounds
US20140031383A1 (en) 2011-02-08 2014-01-30 Dana-Farber Cancer Institute, Inc. Methods for treatment of melanoma
WO2017075559A1 (en) 2015-10-30 2017-05-04 E. I. Du Pont De Nemours And Company Dihydroorotate dehydrogenase inhibitor compositions effective as herbicides
CN111960937B (zh) * 2020-08-20 2022-09-02 广西中医药大学 混源萜类化合物及其制备方法和在制备抗乳腺癌或二氢乳清酸脱氢酶抑制剂药物中的应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL89029A (en) * 1988-01-29 1993-01-31 Lilly Co Eli Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them

Also Published As

Publication number Publication date
JPH06113889A (ja) 1994-04-26
US5976848A (en) 1999-11-02
DE69324831D1 (de) 1999-06-17
EP0554042B1 (de) 1999-05-12
EP0554042A1 (de) 1993-08-04
JP3187585B2 (ja) 2001-07-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee