DE69323264T2 - Pädiatrische Kombinationsvakzine mit verbesserter Immunogenizität jeder Vakzine komponente - Google Patents

Pädiatrische Kombinationsvakzine mit verbesserter Immunogenizität jeder Vakzine komponente

Info

Publication number
DE69323264T2
DE69323264T2 DE69323264T DE69323264T DE69323264T2 DE 69323264 T2 DE69323264 T2 DE 69323264T2 DE 69323264 T DE69323264 T DE 69323264T DE 69323264 T DE69323264 T DE 69323264T DE 69323264 T2 DE69323264 T2 DE 69323264T2
Authority
DE
Germany
Prior art keywords
vaccine
pediatric
improved immunogenicity
component
combined
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69323264T
Other languages
English (en)
Other versions
DE69323264T4 (de
DE69323264D1 (de
Inventor
Peter R Paradiso
Deborah A Hogerman
Dace Viceps Madore
Jill G Hackell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DE69323264T2 publication Critical patent/DE69323264T2/de
Application granted granted Critical
Publication of DE69323264T4 publication Critical patent/DE69323264T4/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6037Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Peptides Or Proteins (AREA)
DE69323264T 1992-10-27 1993-07-22 Pädiatrische Kombinationsvakzine mit verbesserter Immunogenizität jeder Vakzine komponente Expired - Lifetime DE69323264T4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96699592A 1992-10-27 1992-10-27

Publications (2)

Publication Number Publication Date
DE69323264T2 true DE69323264T2 (de) 1999-06-02
DE69323264T4 DE69323264T4 (de) 1999-10-14

Family

ID=25512167

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69323264A Expired - Fee Related DE69323264D1 (de) 1992-10-27 1993-07-22 Pädiatrische Kombinationsvakzine mit verbesserter Immunogenizität jeder Vakzine komponente
DE69323264T Expired - Lifetime DE69323264T4 (de) 1992-10-27 1993-07-22 Pädiatrische Kombinationsvakzine mit verbesserter Immunogenizität jeder Vakzine komponente

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69323264A Expired - Fee Related DE69323264D1 (de) 1992-10-27 1993-07-22 Pädiatrische Kombinationsvakzine mit verbesserter Immunogenizität jeder Vakzine komponente

Country Status (23)

Country Link
EP (1) EP0594950B1 (de)
JP (1) JPH07300427A (de)
KR (1) KR100289224B1 (de)
AT (1) ATE176157T1 (de)
AU (1) AU669570B2 (de)
CA (1) CA2109159A1 (de)
CZ (1) CZ283587B6 (de)
DE (2) DE69323264D1 (de)
DK (1) DK0594950T3 (de)
ES (1) ES2126616T3 (de)
FI (1) FI934725A (de)
GR (1) GR3029884T3 (de)
HK (1) HK1009931A1 (de)
HU (1) HU215149B (de)
IL (1) IL107387A (de)
LV (1) LV12271B (de)
NO (1) NO308588B1 (de)
NZ (1) NZ250029A (de)
PL (1) PL174130B1 (de)
RU (1) RU2121365C1 (de)
SG (1) SG47725A1 (de)
TW (1) TW256774B (de)
UA (1) UA27754C2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1864195A (en) * 1994-03-07 1995-09-25 Auckland Uniservices Limited Prevention of diabetes
DK1090642T3 (da) * 1995-06-07 2008-09-22 Glaxosmithkline Biolog Sa Vacciner omfattende et polysaccharidantigen-bæreprotein-konjugat og frit bæreprotein
EP0833662B2 (de) * 1995-06-23 2011-01-26 SmithKline Beecham Biologicals S.A. Eine Impfstoffzusammensetzung, bestehend aus einem Haemophilus influenzae B Polysaccharid Antigen-Konjugat adsorbiert an Aluminiumphosphat
US20020054884A1 (en) 1995-06-23 2002-05-09 Smithkline Beecham Biologicals, Sa Vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate
CN100408095C (zh) * 1996-07-02 2008-08-06 康诺特实验室有限公司 多价dtp-polio疫苗
GB0108364D0 (en) * 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
EA006313B1 (ru) * 2000-06-29 2005-10-27 Глаксосмитклайн Байолоджикалс С.А. Поливалентные иммуногенные композиции и способы их применения
DE60311526T2 (de) 2002-11-01 2007-10-31 Glaxosmithkline Biologicals S.A. Immunogene zusammensetzung
GB0505996D0 (en) * 2005-03-23 2005-04-27 Glaxosmithkline Biolog Sa Fermentation process
KR20130122810A (ko) 2005-06-27 2013-11-08 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신 제조 방법

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4902506A (en) * 1983-07-05 1990-02-20 The University Of Rochester Immunogenic conjugates

Also Published As

Publication number Publication date
HU215149B (hu) 2000-03-28
TW256774B (de) 1995-09-11
LV12271A (lv) 1999-05-20
HK1009931A1 (en) 1999-06-11
IL107387A (en) 1997-04-15
HU9303028D0 (en) 1994-01-28
GR3029884T3 (en) 1999-07-30
FI934725A0 (fi) 1993-10-26
NO933856D0 (no) 1993-10-26
CA2109159A1 (en) 1994-04-28
KR100289224B1 (ko) 2001-05-02
FI934725A (fi) 1994-04-28
IL107387A0 (en) 1994-01-25
ES2126616T3 (es) 1999-04-01
DK0594950T3 (da) 1999-09-13
NZ250029A (en) 1994-09-27
PL174130B1 (pl) 1998-06-30
CZ283587B6 (cs) 1998-05-13
DE69323264T4 (de) 1999-10-14
LV12271B (en) 1999-07-20
RU2121365C1 (ru) 1998-11-10
JPH07300427A (ja) 1995-11-14
SG47725A1 (en) 1998-04-17
AU669570B2 (en) 1996-06-13
CZ227293A3 (en) 1994-05-18
UA27754C2 (uk) 2000-10-16
EP0594950A1 (de) 1994-05-04
NO933856L (no) 1994-04-28
EP0594950B1 (de) 1999-01-27
ATE176157T1 (de) 1999-02-15
DE69323264D1 (de) 1999-03-11
HUT67239A (en) 1995-03-28
AU5029093A (en) 1994-05-12
KR940008698A (ko) 1994-05-16
NO308588B1 (no) 2000-10-02

Similar Documents

Publication Publication Date Title
AU696338B2 (en) A vaccine composition comprising a polysaccharide conjugate antigen adsorbed onto aluminium phosphate
BR9710460A (pt) Composi-Æo imunolÄgica multi-valente e seu uso em vacinas
GR3035081T3 (en) Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections
FI104046B1 (fi) Menetelmä konjugoidun oligosakkaridin valmistamiseksi
NO179164C (no) Fremgangsmåte for fremstilling av et immunogenkonjugat
DE69323264T4 (de) Pädiatrische Kombinationsvakzine mit verbesserter Immunogenizität jeder Vakzine komponente
RU93048161A (ru) Комбинированная педиатрическая вакцина с усиленной иммуногенностью каждого вакционного компонента
US6165468A (en) Antigenic carbohydrate linked to an immunogenic carrier
Audibert et al. Of antigens, adjuvants, and carriers in synthetic vaccines.
Guo et al. Studies on meningococcal polysaccharide-tetanus toxoid conjugates.
Egorkov et al. Immunological activity of small doses of diphtheria and tetanus toxoids in booster immunization of children with allergically altered responsiveness and adults.
SE8400934D0 (sv) Forfarande for framstellning av lyofiliserade, adsorberade, polyvalenta vacciner