DE69233674D1 - Homogenes Testsystem zur Bestimmung eines Analytes - Google Patents

Homogenes Testsystem zur Bestimmung eines Analytes

Info

Publication number
DE69233674D1
DE69233674D1 DE69233674T DE69233674T DE69233674D1 DE 69233674 D1 DE69233674 D1 DE 69233674D1 DE 69233674 T DE69233674 T DE 69233674T DE 69233674 T DE69233674 T DE 69233674T DE 69233674 D1 DE69233674 D1 DE 69233674D1
Authority
DE
Germany
Prior art keywords
analyte
pacc
medium
sbp
determination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69233674T
Other languages
English (en)
Other versions
DE69233674T2 (de
Inventor
Edwin F Ullman
Hrair Kirakossian
John S Pease
Daniel B Wagner
Yuri Daniloff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Products GmbH
Original Assignee
Dade Behring Marburg GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/704,569 external-priority patent/US6251581B1/en
Priority claimed from US07/718,490 external-priority patent/US5340716A/en
Application filed by Dade Behring Marburg GmbH filed Critical Dade Behring Marburg GmbH
Publication of DE69233674D1 publication Critical patent/DE69233674D1/de
Application granted granted Critical
Publication of DE69233674T2 publication Critical patent/DE69233674T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06—Six-membered rings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles
DE69233674T 1991-05-22 1992-05-21 Homogenes Testsystem zur Bestimmung eines Analytes Expired - Lifetime DE69233674T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/704,569 US6251581B1 (en) 1991-05-22 1991-05-22 Assay method utilizing induced luminescence
US704569 1991-05-22
US07/718,490 US5340716A (en) 1991-06-20 1991-06-20 Assay method utilizing photoactivated chemiluminescent label
US718490 1991-06-20

Publications (2)

Publication Number Publication Date
DE69233674D1 true DE69233674D1 (de) 2007-02-15
DE69233674T2 DE69233674T2 (de) 2007-10-18

Family

ID=27107346

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69233674T Expired - Lifetime DE69233674T2 (de) 1991-05-22 1992-05-21 Homogenes Testsystem zur Bestimmung eines Analytes
DE69233146T Expired - Lifetime DE69233146T2 (de) 1991-05-22 1992-05-21 Partikel, die eine Zusammensetzung beinhalten, die eine chemilumineszierende Verbindung umfassen
DE69232161T Expired - Lifetime DE69232161T2 (de) 1991-05-22 1992-05-21 Bestimmungsmethoden unter Verwendung von induzierter Lumineszenz

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE69233146T Expired - Lifetime DE69233146T2 (de) 1991-05-22 1992-05-21 Partikel, die eine Zusammensetzung beinhalten, die eine chemilumineszierende Verbindung umfassen
DE69232161T Expired - Lifetime DE69232161T2 (de) 1991-05-22 1992-05-21 Bestimmungsmethoden unter Verwendung von induzierter Lumineszenz

Country Status (10)

Country Link
EP (4) EP0515194B1 (de)
JP (1) JP3892912B2 (de)
AT (3) ATE350665T1 (de)
AU (1) AU657134B2 (de)
CA (1) CA2069145C (de)
DE (3) DE69233674T2 (de)
DK (1) DK0984282T3 (de)
ES (3) ES2168092T3 (de)
IL (1) IL101945A (de)
PT (1) PT984282E (de)

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Also Published As

Publication number Publication date
CA2069145C (en) 2007-07-31
DK0984282T3 (da) 2003-11-17
AU1706892A (en) 1992-11-26
EP0984281A3 (de) 2000-06-07
ATE246360T1 (de) 2003-08-15
EP0515194A2 (de) 1992-11-25
IL101945A (en) 1998-02-08
JPH05180773A (ja) 1993-07-23
ES2204050T3 (es) 2004-04-16
AU657134B2 (en) 1995-03-02
ATE208039T1 (de) 2001-11-15
IL101945A0 (en) 1992-12-30
EP1418430A3 (de) 2004-09-01
EP0515194B1 (de) 2001-10-31
DE69232161T2 (de) 2002-05-16
ES2168092T3 (es) 2002-06-01
EP0984281B1 (de) 2007-01-03
CA2069145A1 (en) 1992-11-23
DE69233146D1 (de) 2003-09-04
EP1418430A2 (de) 2004-05-12
EP0984282A2 (de) 2000-03-08
DE69233146T2 (de) 2004-04-29
JP3892912B2 (ja) 2007-03-14
EP0984282A3 (de) 2000-06-07
EP0515194A3 (en) 1993-10-20
DE69233674T2 (de) 2007-10-18
PT984282E (pt) 2003-12-31
EP0984281A2 (de) 2000-03-08
DE69232161D1 (de) 2001-12-06
EP0984282B1 (de) 2003-07-30
ATE350665T1 (de) 2007-01-15
ES2280110T3 (es) 2007-09-01

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