DE69231046D1 - Rekombinante DNS die für eine Kette des T-Zell Rezeptors kodiert, Verfahren zur Herstellung, Antikörper und Arzneimittel die diese enthalten - Google Patents

Rekombinante DNS die für eine Kette des T-Zell Rezeptors kodiert, Verfahren zur Herstellung, Antikörper und Arzneimittel die diese enthalten

Info

Publication number
DE69231046D1
DE69231046D1 DE69231046T DE69231046T DE69231046D1 DE 69231046 D1 DE69231046 D1 DE 69231046D1 DE 69231046 T DE69231046 T DE 69231046T DE 69231046 T DE69231046 T DE 69231046T DE 69231046 D1 DE69231046 D1 DE 69231046D1
Authority
DE
Germany
Prior art keywords
sequence
recombinant dna
antibodies
chain
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69231046T
Other languages
English (en)
Other versions
DE69231046T2 (de
Inventor
Francois Romagne
Agthoven Andre Van
Bernard Malissen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunotech SAS
Original Assignee
Immunotech SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunotech SAS filed Critical Immunotech SAS
Publication of DE69231046D1 publication Critical patent/DE69231046D1/de
Application granted granted Critical
Publication of DE69231046T2 publication Critical patent/DE69231046T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/7051—T-cell receptor (TcR)-CD3 complex
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69231046T 1991-02-15 1992-02-12 Rekombinante DNS die für eine Kette des T-Zell Rezeptors kodiert, Verfahren zur Herstellung, Antikörper und Arzneimittel die diese enthalten Expired - Fee Related DE69231046T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR919102189A FR2672901B1 (fr) 1991-02-15 1991-02-15 Nouvelles molecules de dna recombinants codant pour une chaine du recepteur pour l'antigene des cellules t, procede de preparation, anticorps et medicaments les renfermant.

Publications (2)

Publication Number Publication Date
DE69231046D1 true DE69231046D1 (de) 2000-06-21
DE69231046T2 DE69231046T2 (de) 2001-01-11

Family

ID=9410030

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69231046T Expired - Fee Related DE69231046T2 (de) 1991-02-15 1992-02-12 Rekombinante DNS die für eine Kette des T-Zell Rezeptors kodiert, Verfahren zur Herstellung, Antikörper und Arzneimittel die diese enthalten

Country Status (10)

Country Link
EP (1) EP0499555B1 (de)
JP (1) JPH0591881A (de)
AT (1) ATE193058T1 (de)
CA (1) CA2061266A1 (de)
DE (1) DE69231046T2 (de)
DK (1) DK0499555T3 (de)
ES (1) ES2147725T3 (de)
FR (1) FR2672901B1 (de)
GR (1) GR3034176T3 (de)
PT (1) PT499555E (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE228166T1 (de) 1994-05-02 2002-12-15 Bernd Groner Bifunktionelles protein, herstellung und verwendung
WO2006036445A2 (en) 2004-09-24 2006-04-06 Trustees Of Dartmouth College Chimeric nk receptor and methods for treating cancer
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
CN110511278A (zh) 2012-05-07 2019-11-29 达特茅斯大学理事会 抗b7-h6抗体、融合蛋白及其使用方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL86278A (en) * 1988-05-04 2003-06-24 Yeda Res & Dev Endowing cells with antibody specificity using chimeric t cell receptor
CA2018248A1 (en) * 1989-06-07 1990-12-07 Clyde W. Shearman Monoclonal antibodies against the human alpha/beta t-cell receptor, their production and use

Also Published As

Publication number Publication date
FR2672901B1 (fr) 1994-09-30
GR3034176T3 (en) 2000-11-30
PT499555E (pt) 2000-10-31
JPH0591881A (ja) 1993-04-16
ES2147725T3 (es) 2000-10-01
DK0499555T3 (da) 2000-10-09
CA2061266A1 (fr) 1992-08-16
EP0499555B1 (de) 2000-05-17
EP0499555A1 (de) 1992-08-19
FR2672901A1 (fr) 1992-08-21
ATE193058T1 (de) 2000-06-15
DE69231046T2 (de) 2001-01-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee