DE69225821D1 - Penamderivate und Verfahren zu deren Herstellung - Google Patents
Penamderivate und Verfahren zu deren HerstellungInfo
- Publication number
- DE69225821D1 DE69225821D1 DE69225821T DE69225821T DE69225821D1 DE 69225821 D1 DE69225821 D1 DE 69225821D1 DE 69225821 T DE69225821 T DE 69225821T DE 69225821 T DE69225821 T DE 69225821T DE 69225821 D1 DE69225821 D1 DE 69225821D1
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- penam derivatives
- penam
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3047085A JP3025910B2 (ja) | 1991-03-13 | 1991-03-13 | ペナム誘導体及びその製造法 |
JP3047166A JP3025911B2 (ja) | 1991-03-13 | 1991-03-13 | 2−エキソメチレンペナムオキシド誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69225821D1 true DE69225821D1 (de) | 1998-07-16 |
DE69225821T2 DE69225821T2 (de) | 1998-11-05 |
Family
ID=26387239
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69225821T Expired - Fee Related DE69225821T2 (de) | 1991-03-13 | 1992-03-11 | Penamderivate und Verfahren zu deren Herstellung |
Country Status (3)
Country | Link |
---|---|
US (1) | US5599925A (de) |
EP (1) | EP0503597B1 (de) |
DE (1) | DE69225821T2 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5686441A (en) * | 1995-08-04 | 1997-11-11 | Syphar Laboratories, Inc. | Penam sulfones as β-lactamase inhibitors |
US20050053976A1 (en) * | 1996-06-06 | 2005-03-10 | Baker Brenda F. | Chimeric oligomeric compounds and their use in gene modulation |
US20040147022A1 (en) * | 1996-06-06 | 2004-07-29 | Baker Brenda F. | 2'-methoxy substituted oligomeric compounds and compositions for use in gene modulations |
US9096636B2 (en) | 1996-06-06 | 2015-08-04 | Isis Pharmaceuticals, Inc. | Chimeric oligomeric compounds and their use in gene modulation |
US7812149B2 (en) * | 1996-06-06 | 2010-10-12 | Isis Pharmaceuticals, Inc. | 2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations |
US20040203024A1 (en) * | 1996-06-06 | 2004-10-14 | Baker Brenda F. | Modified oligonucleotides for use in RNA interference |
US20040171031A1 (en) * | 1996-06-06 | 2004-09-02 | Baker Brenda F. | Sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation |
US5898031A (en) * | 1996-06-06 | 1999-04-27 | Isis Pharmaceuticals, Inc. | Oligoribonucleotides for cleaving RNA |
JPH10245386A (ja) * | 1997-03-05 | 1998-09-14 | Otsuka Chem Co Ltd | エキソメチレンペナム化合物の製造方法 |
AU2003295387A1 (en) * | 2002-11-05 | 2004-06-03 | Isis Parmaceuticals, Inc. | Modified oligonucleotides for use in rna interference |
WO2004113496A2 (en) * | 2003-06-20 | 2004-12-29 | Isis Pharmaceuticals, Inc. | Double stranded compositions comprising a 3’-endo modified strand for use in gene modulation |
EP1636342A4 (de) * | 2003-06-20 | 2008-10-08 | Isis Pharmaceuticals Inc | Oligomere verbindungen zur verwendung bei der modulation von genen |
US8569474B2 (en) * | 2004-03-09 | 2013-10-29 | Isis Pharmaceuticals, Inc. | Double stranded constructs comprising one or more short strands hybridized to a longer strand |
US8394947B2 (en) * | 2004-06-03 | 2013-03-12 | Isis Pharmaceuticals, Inc. | Positionally modified siRNA constructs |
AU2005252662B2 (en) * | 2004-06-03 | 2011-08-18 | Isis Pharmaceuticals, Inc. | Double strand compositions comprising differentially modified strands for use in gene modulation |
US7884086B2 (en) * | 2004-09-08 | 2011-02-08 | Isis Pharmaceuticals, Inc. | Conjugates for use in hepatocyte free uptake assays |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4331677A (en) * | 1978-11-24 | 1982-05-25 | Farmitalia Carlo Erba S.P.A. | 7-Oxo-4-1-aza-bicyclo-[3,2,0]-heptane derivatives |
US4797396A (en) * | 1984-07-02 | 1989-01-10 | Merck & Co., Inc. | β-Lactam derivatives as anti-inflammatory and antidegenerative agents |
US4861768A (en) * | 1986-02-27 | 1989-08-29 | Taiho Pharmaceutical Company, Limited | 2 β-substituted thiomethylpenicillin derivatives and their preparation and use |
GB8714413D0 (en) * | 1987-06-19 | 1987-07-22 | Erba Farmitalia | 6-substituted penem esters |
JP2603082B2 (ja) * | 1987-09-07 | 1997-04-23 | 大塚化学株式会社 | ペニシラン酸誘導体の製造法 |
US4992543A (en) * | 1988-10-19 | 1991-02-12 | Pfizer Inc. | Penem derivatives |
CA2001642A1 (en) * | 1988-10-31 | 1990-04-30 | David J. Bartkovitz | Penicillanic acid derivatives |
IT1239275B (it) * | 1990-05-16 | 1993-10-01 | Menarini Farma Ind | Penem ditiocarbammati, loro uso e procedimento di fabbricazione relativi |
-
1992
- 1992-03-11 DE DE69225821T patent/DE69225821T2/de not_active Expired - Fee Related
- 1992-03-11 EP EP92104192A patent/EP0503597B1/de not_active Expired - Lifetime
-
1994
- 1994-09-30 US US08/314,307 patent/US5599925A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0503597A2 (de) | 1992-09-16 |
EP0503597A3 (en) | 1992-12-09 |
US5599925A (en) | 1997-02-04 |
DE69225821T2 (de) | 1998-11-05 |
EP0503597B1 (de) | 1998-06-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |