DE69223736T2 - Acridine-1,8-Dionderivate als therapeutisches Mittel - Google Patents
Acridine-1,8-Dionderivate als therapeutisches MittelInfo
- Publication number
- DE69223736T2 DE69223736T2 DE69223736T DE69223736T DE69223736T2 DE 69223736 T2 DE69223736 T2 DE 69223736T2 DE 69223736 T DE69223736 T DE 69223736T DE 69223736 T DE69223736 T DE 69223736T DE 69223736 T2 DE69223736 T2 DE 69223736T2
- Authority
- DE
- Germany
- Prior art keywords
- acridine
- therapeutic agents
- dione derivatives
- compound
- acridinedione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919122305A GB9122305D0 (en) | 1991-10-21 | 1991-10-21 | Therapeutic agents |
| GB929213538A GB9213538D0 (en) | 1992-06-25 | 1992-06-25 | Therapeutic agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69223736D1 DE69223736D1 (de) | 1998-02-05 |
| DE69223736T2 true DE69223736T2 (de) | 1998-05-07 |
Family
ID=26299722
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69223736T Expired - Fee Related DE69223736T2 (de) | 1991-10-21 | 1992-10-20 | Acridine-1,8-Dionderivate als therapeutisches Mittel |
| DE69219271T Expired - Fee Related DE69219271T2 (de) | 1991-10-21 | 1992-10-20 | Acridinederivat als therapeutisches Mittel |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69219271T Expired - Fee Related DE69219271T2 (de) | 1991-10-21 | 1992-10-20 | Acridinederivat als therapeutisches Mittel |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5258390A (de) |
| EP (1) | EP0539153B1 (de) |
| JP (1) | JP3157924B2 (de) |
| KR (1) | KR930007907A (de) |
| AT (1) | ATE152103T1 (de) |
| AU (1) | AU659500B2 (de) |
| CA (1) | CA2080950A1 (de) |
| CZ (1) | CZ317592A3 (de) |
| DE (2) | DE69223736T2 (de) |
| FI (1) | FI924744A (de) |
| GB (1) | GB9220570D0 (de) |
| HU (1) | HUT65626A (de) |
| IL (1) | IL103478A0 (de) |
| MY (1) | MY106661A (de) |
| NO (1) | NO178696C (de) |
| NZ (1) | NZ244822A (de) |
| PL (1) | PL169716B1 (de) |
| TW (1) | TW223061B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9214120D0 (en) * | 1991-07-25 | 1992-08-12 | Ici Plc | Therapeutic amides |
| CA2080949A1 (en) * | 1991-10-21 | 1993-04-22 | Cyrus John Ohnmacht | Therapeutic agents |
| GB9318935D0 (en) * | 1992-10-20 | 1993-10-27 | Zeneca Ltd | Heterocyclic derivatives |
| US5455253A (en) * | 1992-10-20 | 1995-10-03 | Zeneca Limited | Heterocyclic derivatives |
| GB9310069D0 (en) * | 1993-05-17 | 1993-06-30 | Zeneca Ltd | Heterocyclic compounds |
| GB9407432D0 (en) * | 1994-04-14 | 1994-06-08 | Zeneca Ltd | Heterocyclic derivative |
| WO1996027375A2 (en) | 1995-03-03 | 1996-09-12 | Algos Pharmaceutical Corporation | Use of dextromethorphan or dextrorphan for the treatment of urinary incontinence |
| GB9707695D0 (en) * | 1996-08-07 | 1997-06-04 | Hoffmann La Roche | Tricyclic dione derivatives |
| US7030096B1 (en) * | 1997-02-13 | 2006-04-18 | Albert Einstein College Of Medicine Of Yeshiva University | Method of enhancing relaxation of penile smooth muscle by introduction of DNA encoding maxi-K potassium channel protein |
| US6191140B1 (en) | 1998-10-28 | 2001-02-20 | Abbott Laboratories | Pyrano, piperidino, and thiopyrano compounds and methods of use |
| US6642222B2 (en) | 1998-10-28 | 2003-11-04 | Abbott Laboratories | Pyrano, piperidino, and thiopyrano compounds and methods of use |
| EP1131322A2 (de) * | 1998-10-28 | 2001-09-12 | Abbott Laboratories | Dihydropyridin verbindungen und ihre verwendung als kalium kanal öffner |
| US6518279B2 (en) | 1999-03-04 | 2003-02-11 | Abbott Laboratories | Cyclopentanone dihydropyridine compounds useful as potassium channel openers |
| TWI287984B (en) * | 2000-10-17 | 2007-10-11 | Wyeth Corp | Pharmaceutical composition for modulating bladder function |
| US20020183395A1 (en) | 2001-04-04 | 2002-12-05 | Wyeth | Methods for treating hyperactive gastric motility |
| EP1688141A1 (de) | 2005-01-31 | 2006-08-09 | elbion AG | Verwendung von Flupirtine zur Behandlung der hyperaktiven Blase und damit zusammenhängender Erkrankungen und zur Behandlung des Reizdarmsyndroms |
| EP1896112A4 (de) * | 2005-06-07 | 2011-04-27 | A M S Res Corp | Injektionsführsystem und verfahren |
| JP2009526079A (ja) | 2006-02-10 | 2009-07-16 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | カリウムチャンネル開放物質としての新規な三環式ジヒドロピラジン |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3454577A (en) * | 1965-11-09 | 1969-07-08 | Hoffmann La Roche | 4-(1,2,3,4,5,6,7,8 - octahydro - 1,8 - dioxo-9-acridanyl) - benzenesulfonamide and derivatives |
| DE2003148A1 (de) * | 1970-01-24 | 1971-07-29 | Bayer Ag | Neue 1,4-Dihydropyridinderivate |
| DE2018738A1 (en) * | 1970-04-18 | 1971-10-28 | Farbenfabriken Bayer Ag, 5090 Leverkusen | Hydrogenated pyridines, quinolines andacridi |
| US4021434A (en) * | 1972-01-22 | 1977-05-03 | Yamanouchi Pharmaceutical Co., Ltd. | Sodium β-[2,6-dimethyl-3,5-bis(ethoxycarbonyl)-4-(3-nitrophenyl)-1,4-dihydropyridine-1-yl]ethyl sulfate |
| DE2242106A1 (de) * | 1972-08-26 | 1974-03-21 | Agfa Gevaert Ag | Lichtempfindliches photographisches material |
| DE2718130C2 (de) * | 1977-04-23 | 1979-05-17 | Du Pont De Nemours (Deutschland) Gmbh, 4000 Duesseldorf | lichtempfindliches Aufzeichnungsmaterial |
| US4546186A (en) * | 1983-12-14 | 1985-10-08 | American Home Products Corporation | 1,4,5,6,7,8-Hexahydro-2-methyl-5-oxo-4-(2-thiazolyl)-3-quinoline carboxylic acid 2-methyl(phenylmethyl)amino ethyl ester and pharmaceutically acceptable salts |
-
1992
- 1992-09-30 GB GB929220570A patent/GB9220570D0/en active Pending
- 1992-10-20 KR KR1019920019226A patent/KR930007907A/ko not_active Application Discontinuation
- 1992-10-20 US US07/963,798 patent/US5258390A/en not_active Expired - Lifetime
- 1992-10-20 MY MYPI92001895A patent/MY106661A/en unknown
- 1992-10-20 TW TW081108329A patent/TW223061B/zh active
- 1992-10-20 NO NO924066A patent/NO178696C/no unknown
- 1992-10-20 CA CA002080950A patent/CA2080950A1/en not_active Abandoned
- 1992-10-20 DE DE69223736T patent/DE69223736T2/de not_active Expired - Fee Related
- 1992-10-20 AT AT92309566T patent/ATE152103T1/de not_active IP Right Cessation
- 1992-10-20 CZ CS923175A patent/CZ317592A3/cs unknown
- 1992-10-20 NZ NZ244822A patent/NZ244822A/en unknown
- 1992-10-20 DE DE69219271T patent/DE69219271T2/de not_active Expired - Fee Related
- 1992-10-20 AU AU27139/92A patent/AU659500B2/en not_active Ceased
- 1992-10-20 JP JP28186292A patent/JP3157924B2/ja not_active Expired - Fee Related
- 1992-10-20 FI FI924744A patent/FI924744A/fi not_active Application Discontinuation
- 1992-10-20 EP EP92309566A patent/EP0539153B1/de not_active Expired - Lifetime
- 1992-10-20 PL PL92296229A patent/PL169716B1/pl unknown
- 1992-10-20 HU HU9203288A patent/HUT65626A/hu unknown
- 1992-10-20 IL IL92103478A patent/IL103478A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69219271D1 (de) | 1997-05-28 |
| EP0539153B1 (de) | 1997-04-23 |
| US5258390A (en) | 1993-11-02 |
| PL296229A1 (en) | 1993-10-04 |
| MY106661A (en) | 1995-07-31 |
| DE69223736D1 (de) | 1998-02-05 |
| CZ317592A3 (en) | 1993-05-12 |
| EP0539153A1 (de) | 1993-04-28 |
| NZ244822A (en) | 1994-10-26 |
| NO924066L (no) | 1993-04-22 |
| JPH05201986A (ja) | 1993-08-10 |
| NO924066D0 (no) | 1992-10-20 |
| NO178696C (no) | 1996-05-15 |
| GB9220570D0 (en) | 1992-11-11 |
| TW223061B (en) | 1994-05-01 |
| FI924744A (fi) | 1993-04-22 |
| ATE152103T1 (de) | 1997-05-15 |
| AU2713992A (en) | 1993-04-22 |
| PL169716B1 (pl) | 1996-08-30 |
| AU659500B2 (en) | 1995-05-18 |
| JP3157924B2 (ja) | 2001-04-23 |
| KR930007907A (ko) | 1993-05-20 |
| HUT65626A (en) | 1994-07-28 |
| IL103478A0 (en) | 1993-03-15 |
| NO178696B (no) | 1996-02-05 |
| FI924744A0 (fi) | 1992-10-20 |
| HU9203288D0 (en) | 1992-12-28 |
| CA2080950A1 (en) | 1993-04-22 |
| DE69219271T2 (de) | 1997-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: ASTRAZENECA UK LTD., LONDON, GB |
|
| 8339 | Ceased/non-payment of the annual fee |