ATE152103T1 - Acridinederivat als therapeutisches mittel - Google Patents

Acridinederivat als therapeutisches mittel

Info

Publication number
ATE152103T1
ATE152103T1 AT92309566T AT92309566T ATE152103T1 AT E152103 T1 ATE152103 T1 AT E152103T1 AT 92309566 T AT92309566 T AT 92309566T AT 92309566 T AT92309566 T AT 92309566T AT E152103 T1 ATE152103 T1 AT E152103T1
Authority
AT
Austria
Prior art keywords
therapeutic agent
acridine derivative
compound
acridine
derivative
Prior art date
Application number
AT92309566T
Other languages
English (en)
Inventor
Cyrus John Ohnmacht
Road Murphy
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919122305A external-priority patent/GB9122305D0/en
Priority claimed from GB929213538A external-priority patent/GB9213538D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Application granted granted Critical
Publication of ATE152103T1 publication Critical patent/ATE152103T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/06Anti-spasmodics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT92309566T 1991-10-21 1992-10-20 Acridinederivat als therapeutisches mittel ATE152103T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919122305A GB9122305D0 (en) 1991-10-21 1991-10-21 Therapeutic agents
GB929213538A GB9213538D0 (en) 1992-06-25 1992-06-25 Therapeutic agent

Publications (1)

Publication Number Publication Date
ATE152103T1 true ATE152103T1 (de) 1997-05-15

Family

ID=26299722

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92309566T ATE152103T1 (de) 1991-10-21 1992-10-20 Acridinederivat als therapeutisches mittel

Country Status (18)

Country Link
US (1) US5258390A (de)
EP (1) EP0539153B1 (de)
JP (1) JP3157924B2 (de)
KR (1) KR930007907A (de)
AT (1) ATE152103T1 (de)
AU (1) AU659500B2 (de)
CA (1) CA2080950A1 (de)
CZ (1) CZ317592A3 (de)
DE (2) DE69223736T2 (de)
FI (1) FI924744A (de)
GB (1) GB9220570D0 (de)
HU (1) HUT65626A (de)
IL (1) IL103478A0 (de)
MY (1) MY106661A (de)
NO (1) NO178696C (de)
NZ (1) NZ244822A (de)
PL (1) PL169716B1 (de)
TW (1) TW223061B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9214120D0 (en) * 1991-07-25 1992-08-12 Ici Plc Therapeutic amides
CA2080949A1 (en) * 1991-10-21 1993-04-22 Cyrus John Ohnmacht Therapeutic agents
GB9318935D0 (en) * 1992-10-20 1993-10-27 Zeneca Ltd Heterocyclic derivatives
US5455253A (en) * 1992-10-20 1995-10-03 Zeneca Limited Heterocyclic derivatives
GB9310069D0 (en) * 1993-05-17 1993-06-30 Zeneca Ltd Heterocyclic compounds
GB9407432D0 (en) * 1994-04-14 1994-06-08 Zeneca Ltd Heterocyclic derivative
WO1996027375A2 (en) 1995-03-03 1996-09-12 Algos Pharmaceutical Corporation Use of dextromethorphan or dextrorphan for the treatment of urinary incontinence
GB9707695D0 (en) * 1996-08-07 1997-06-04 Hoffmann La Roche Tricyclic dione derivatives
US7030096B1 (en) * 1997-02-13 2006-04-18 Albert Einstein College Of Medicine Of Yeshiva University Method of enhancing relaxation of penile smooth muscle by introduction of DNA encoding maxi-K potassium channel protein
US6191140B1 (en) 1998-10-28 2001-02-20 Abbott Laboratories Pyrano, piperidino, and thiopyrano compounds and methods of use
US6642222B2 (en) 1998-10-28 2003-11-04 Abbott Laboratories Pyrano, piperidino, and thiopyrano compounds and methods of use
EP1131322A2 (de) * 1998-10-28 2001-09-12 Abbott Laboratories Dihydropyridin verbindungen und ihre verwendung als kalium kanal öffner
US6518279B2 (en) 1999-03-04 2003-02-11 Abbott Laboratories Cyclopentanone dihydropyridine compounds useful as potassium channel openers
TWI287984B (en) * 2000-10-17 2007-10-11 Wyeth Corp Pharmaceutical composition for modulating bladder function
US20020183395A1 (en) 2001-04-04 2002-12-05 Wyeth Methods for treating hyperactive gastric motility
EP1688141A1 (de) 2005-01-31 2006-08-09 elbion AG Verwendung von Flupirtine zur Behandlung der hyperaktiven Blase und damit zusammenhängender Erkrankungen und zur Behandlung des Reizdarmsyndroms
EP1896112A4 (de) * 2005-06-07 2011-04-27 A M S Res Corp Injektionsführsystem und verfahren
JP2009526079A (ja) 2006-02-10 2009-07-16 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ カリウムチャンネル開放物質としての新規な三環式ジヒドロピラジン

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3454577A (en) * 1965-11-09 1969-07-08 Hoffmann La Roche 4-(1,2,3,4,5,6,7,8 - octahydro - 1,8 - dioxo-9-acridanyl) - benzenesulfonamide and derivatives
DE2003148A1 (de) * 1970-01-24 1971-07-29 Bayer Ag Neue 1,4-Dihydropyridinderivate
DE2018738A1 (en) * 1970-04-18 1971-10-28 Farbenfabriken Bayer Ag, 5090 Leverkusen Hydrogenated pyridines, quinolines andacridi
US4021434A (en) * 1972-01-22 1977-05-03 Yamanouchi Pharmaceutical Co., Ltd. Sodium β-[2,6-dimethyl-3,5-bis(ethoxycarbonyl)-4-(3-nitrophenyl)-1,4-dihydropyridine-1-yl]ethyl sulfate
DE2242106A1 (de) * 1972-08-26 1974-03-21 Agfa Gevaert Ag Lichtempfindliches photographisches material
DE2718130C2 (de) * 1977-04-23 1979-05-17 Du Pont De Nemours (Deutschland) Gmbh, 4000 Duesseldorf lichtempfindliches Aufzeichnungsmaterial
US4546186A (en) * 1983-12-14 1985-10-08 American Home Products Corporation 1,4,5,6,7,8-Hexahydro-2-methyl-5-oxo-4-(2-thiazolyl)-3-quinoline carboxylic acid 2-methyl(phenylmethyl)amino ethyl ester and pharmaceutically acceptable salts

Also Published As

Publication number Publication date
DE69219271D1 (de) 1997-05-28
EP0539153B1 (de) 1997-04-23
US5258390A (en) 1993-11-02
PL296229A1 (en) 1993-10-04
DE69223736T2 (de) 1998-05-07
MY106661A (en) 1995-07-31
DE69223736D1 (de) 1998-02-05
CZ317592A3 (en) 1993-05-12
EP0539153A1 (de) 1993-04-28
NZ244822A (en) 1994-10-26
NO924066L (no) 1993-04-22
JPH05201986A (ja) 1993-08-10
NO924066D0 (no) 1992-10-20
NO178696C (no) 1996-05-15
GB9220570D0 (en) 1992-11-11
TW223061B (en) 1994-05-01
FI924744A (fi) 1993-04-22
AU2713992A (en) 1993-04-22
PL169716B1 (pl) 1996-08-30
AU659500B2 (en) 1995-05-18
JP3157924B2 (ja) 2001-04-23
KR930007907A (ko) 1993-05-20
HUT65626A (en) 1994-07-28
IL103478A0 (en) 1993-03-15
NO178696B (no) 1996-02-05
FI924744A0 (fi) 1992-10-20
HU9203288D0 (en) 1992-12-28
CA2080950A1 (en) 1993-04-22
DE69219271T2 (de) 1997-08-07

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties