DE69223206D1 - Anti-menschliche Milchfettglobule humanisierte Antikörper - Google Patents

Anti-menschliche Milchfettglobule humanisierte Antikörper

Info

Publication number
DE69223206D1
DE69223206D1 DE69223206T DE69223206T DE69223206D1 DE 69223206 D1 DE69223206 D1 DE 69223206D1 DE 69223206 T DE69223206 T DE 69223206T DE 69223206 T DE69223206 T DE 69223206T DE 69223206 D1 DE69223206 D1 DE 69223206D1
Authority
DE
Germany
Prior art keywords
hams
derived
milk fat
human milk
humanized antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69223206T
Other languages
English (en)
Other versions
DE69223206T2 (de
Inventor
John Robert Adair
Philip R Hamann
Raymond John Owens
Terence Seward Baker
Alan Howard Lyons
Lois M Hinman
Ana T Menendez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Celltech Ltd
Original Assignee
Celltech R&D Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech R&D Ltd filed Critical Celltech R&D Ltd
Publication of DE69223206D1 publication Critical patent/DE69223206D1/de
Application granted granted Critical
Publication of DE69223206T2 publication Critical patent/DE69223206T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3015—Breast
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6851—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell
    • A61K47/6855—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a determinant of a tumour cell the tumour determinant being from breast cancer cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69223206T 1991-09-26 1992-09-24 Anti-menschliche Milchfettglobule humanisierte Antikörper Expired - Lifetime DE69223206T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919120467A GB9120467D0 (en) 1991-09-26 1991-09-26 Anti-hmfg antibodies and process for their production

Publications (2)

Publication Number Publication Date
DE69223206D1 true DE69223206D1 (de) 1998-01-02
DE69223206T2 DE69223206T2 (de) 1998-06-25

Family

ID=10701993

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69223206T Expired - Lifetime DE69223206T2 (de) 1991-09-26 1992-09-24 Anti-menschliche Milchfettglobule humanisierte Antikörper
DE69232991T Expired - Lifetime DE69232991T2 (de) 1991-09-26 1992-09-24 Anti-menschliche Milchfettglobule humanisierte Antikörper und Verfahren zu ihrer Herstellung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69232991T Expired - Lifetime DE69232991T2 (de) 1991-09-26 1992-09-24 Anti-menschliche Milchfettglobule humanisierte Antikörper und Verfahren zu ihrer Herstellung

Country Status (13)

Country Link
US (1) US6506881B1 (de)
EP (2) EP0781845B1 (de)
JP (1) JP3498957B2 (de)
AT (2) ATE160362T1 (de)
AU (1) AU666868B2 (de)
CA (1) CA2095926C (de)
DE (2) DE69223206T2 (de)
DK (1) DK0781845T3 (de)
ES (1) ES2108732T3 (de)
GB (1) GB9120467D0 (de)
IL (1) IL103269A (de)
NZ (1) NZ244468A (de)
WO (1) WO1993006231A1 (de)

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GB202210679D0 (en) 2022-07-21 2022-09-07 Dualyx Nv Binding molecules targeting il-12rb2
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Also Published As

Publication number Publication date
EP0781845A2 (de) 1997-07-02
JPH06505399A (ja) 1994-06-23
CA2095926C (en) 2002-07-16
IL103269A (en) 1998-01-04
ATE236251T1 (de) 2003-04-15
EP0534742B1 (de) 1997-11-19
AU666868B2 (en) 1996-02-29
DE69232991T2 (de) 2004-01-15
ATE160362T1 (de) 1997-12-15
DE69223206T2 (de) 1998-06-25
EP0534742A1 (de) 1993-03-31
EP0781845B1 (de) 2003-04-02
NZ244468A (en) 1994-11-25
DK0781845T3 (da) 2003-06-16
EP0781845A3 (de) 1997-07-09
GB9120467D0 (en) 1991-11-06
US6506881B1 (en) 2003-01-14
ES2108732T3 (es) 1998-01-01
AU2598392A (en) 1993-04-27
DE69232991D1 (de) 2003-05-08
IL103269A0 (en) 1993-02-21
JP3498957B2 (ja) 2004-02-23
WO1993006231A1 (en) 1993-04-01
CA2095926A1 (en) 1993-03-27

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