DE69222636D1 - Anti-hiv protein, tap-29, aus trichosanthes, seine kodierende dna und therapeutischen anwendungen - Google Patents

Anti-hiv protein, tap-29, aus trichosanthes, seine kodierende dna und therapeutischen anwendungen

Info

Publication number
DE69222636D1
DE69222636D1 DE69222636T DE69222636T DE69222636D1 DE 69222636 D1 DE69222636 D1 DE 69222636D1 DE 69222636 T DE69222636 T DE 69222636T DE 69222636 T DE69222636 T DE 69222636T DE 69222636 D1 DE69222636 D1 DE 69222636D1
Authority
DE
Germany
Prior art keywords
protein
tap
trichosanthes
therapeutic applications
encoding dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69222636T
Other languages
English (en)
Other versions
DE69222636T2 (de
Inventor
Sylvia Lee-Huang
Philip Huang
Hao-Chia Chen
Hsiang-Fu Kung
Peter Huang
Henry Huang
Paul Huang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
New York University NYU
Abraxis Bioscience LLC
Original Assignee
US Department of Health and Human Services
American Bioscience Inc
New York University NYU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services, American Bioscience Inc, New York University NYU filed Critical US Department of Health and Human Services
Publication of DE69222636D1 publication Critical patent/DE69222636D1/de
Application granted granted Critical
Publication of DE69222636T2 publication Critical patent/DE69222636T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/16—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69222636T 1991-04-15 1992-04-15 Anti-hiv protein, tap-29, aus trichosanthes, seine kodierende dna und therapeutischen anwendungen Expired - Fee Related DE69222636T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68512691A 1991-04-15 1991-04-15
PCT/US1992/003089 WO1992018148A1 (en) 1991-04-15 1992-04-15 An anti-hiv protein, tap 29, from trichosanthes, dna coding therefor and therapeutic uses thereof

Publications (2)

Publication Number Publication Date
DE69222636D1 true DE69222636D1 (de) 1997-11-13
DE69222636T2 DE69222636T2 (de) 1998-02-05

Family

ID=24750879

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69222636T Expired - Fee Related DE69222636T2 (de) 1991-04-15 1992-04-15 Anti-hiv protein, tap-29, aus trichosanthes, seine kodierende dna und therapeutischen anwendungen

Country Status (11)

Country Link
US (1) US5532214A (de)
EP (1) EP0580782B1 (de)
JP (1) JPH06506949A (de)
AT (1) ATE159032T1 (de)
AU (1) AU672749B2 (de)
CA (1) CA2108467A1 (de)
DE (1) DE69222636T2 (de)
DK (1) DK0580782T3 (de)
ES (1) ES2111068T3 (de)
GR (1) GR3025841T3 (de)
WO (1) WO1992018148A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635384A (en) * 1990-06-11 1997-06-03 Dowelanco Ribosome-inactivating proteins, inactive precursor forms thereof, a process for making and a method of using
US5681815A (en) * 1993-06-28 1997-10-28 Sophie Chen Antiviral and antitumor agents
EP0948347A4 (de) * 1997-07-16 2000-08-30 Sophie Chen Anti-virale und anti-tumor wirkstoffe
CN1152051C (zh) 2000-08-02 2004-06-02 北京翔天牧生物科技有限公司 一种天花粉蛋白突变体及制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601680B1 (fr) * 1986-07-15 1990-06-29 Sanofi Sa Inhibiteur de la synthese proteique, procede d'isolement, utilisation et compositions pharmaceutiques en contenant
US4985541A (en) * 1987-04-10 1991-01-15 Zymogenetics, Inc. Novel cytotoxic protein
US5149528A (en) * 1987-04-10 1992-09-22 Zymogenetics, Inc. Cytotoxic protein from Trichosanthes kirilowii
US4869903A (en) * 1987-05-29 1989-09-26 Genelabs Incorporated Method of selectively inhibiting HIV
US4795739A (en) * 1987-05-29 1989-01-03 Gene Labs, Inc. Method of inhibiting HIV
US5166056A (en) * 1989-04-04 1992-11-24 Genelabs Incorporated Recombinant trichosanthin and coding sequence
JPH04504208A (ja) * 1989-04-04 1992-07-30 ジエネラブス・テクノロジーズ・インコーポレイテツド 組換えトリコサンチンおよびコード配列
US5077390A (en) * 1989-04-04 1991-12-31 Genelabs, Incorporated Purified trichosanthin and method of preparation

Also Published As

Publication number Publication date
EP0580782B1 (de) 1997-10-08
GR3025841T3 (en) 1998-04-30
JPH06506949A (ja) 1994-08-04
US5532214A (en) 1996-07-02
WO1992018148A1 (en) 1992-10-29
EP0580782A1 (de) 1994-02-02
ES2111068T3 (es) 1998-03-01
EP0580782A4 (de) 1995-04-26
AU672749B2 (en) 1996-10-17
ATE159032T1 (de) 1997-10-15
AU1973792A (en) 1992-11-17
DK0580782T3 (da) 1998-05-04
DE69222636T2 (de) 1998-02-05
CA2108467A1 (en) 1992-10-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee