DE69130611T2 - Hydroxycholesterol enthaltende pharmazeutsiche zusammensetzungen und deren verwendung in medikamenten - Google Patents

Hydroxycholesterol enthaltende pharmazeutsiche zusammensetzungen und deren verwendung in medikamenten

Info

Publication number
DE69130611T2
DE69130611T2 DE69130611T DE69130611T DE69130611T2 DE 69130611 T2 DE69130611 T2 DE 69130611T2 DE 69130611 T DE69130611 T DE 69130611T DE 69130611 T DE69130611 T DE 69130611T DE 69130611 T2 DE69130611 T2 DE 69130611T2
Authority
DE
Germany
Prior art keywords
hydroxycholesterol
medications
pharmaceutical compositions
containing pharmaceutical
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69130611T
Other languages
English (en)
Other versions
DE69130611D1 (de
Inventor
Patrick Behr
Alexandre Kupferberg
Marcel Mersel
Alain Privat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Original Assignee
Centre National de la Recherche Scientifique CNRS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre National de la Recherche Scientifique CNRS filed Critical Centre National de la Recherche Scientifique CNRS
Publication of DE69130611D1 publication Critical patent/DE69130611D1/de
Application granted granted Critical
Publication of DE69130611T2 publication Critical patent/DE69130611T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/06—Hydroxylating

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Steroid Compounds (AREA)
DE69130611T 1990-07-25 1991-07-24 Hydroxycholesterol enthaltende pharmazeutsiche zusammensetzungen und deren verwendung in medikamenten Expired - Lifetime DE69130611T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9009501A FR2665179B1 (fr) 1990-07-25 1990-07-25 Procede d'hydroxylation d'un radical methylene acyclique ou cyclique en position allylique, composition pharmaceutique contenant des esters d'hydroxycholesterol et utilisation de ces compositions pour la preparation de medicaments.
PCT/FR1991/000608 WO1992001803A1 (fr) 1990-07-25 1991-07-24 Procede d'hydroxylation d'un radical methylene acyclique ou cyclique en position allylique, composition pharmaceutique contenant des derives d'hydroxycholesterol et utilisation de ces compositions pour la preparation de medicaments

Publications (2)

Publication Number Publication Date
DE69130611D1 DE69130611D1 (de) 1999-01-21
DE69130611T2 true DE69130611T2 (de) 1999-08-26

Family

ID=9399087

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69130611T Expired - Lifetime DE69130611T2 (de) 1990-07-25 1991-07-24 Hydroxycholesterol enthaltende pharmazeutsiche zusammensetzungen und deren verwendung in medikamenten

Country Status (6)

Country Link
US (1) US6423702B1 (de)
EP (1) EP0540649B1 (de)
JP (1) JP3133327B2 (de)
DE (1) DE69130611T2 (de)
FR (1) FR2665179B1 (de)
WO (1) WO1992001803A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5826678A (en) * 1997-05-08 1998-10-27 Yu; Yu-Li Fire escape parachute
JP2003238540A (ja) * 2002-02-08 2003-08-27 Bayer Ag テトラゾール誘導体及び除草剤
EP2433619A1 (de) * 2010-09-24 2012-03-28 Intsel Chimos Neuartiger Antitumorwirkstoff und therapeutische Verwendungen dafür
NL2035768A (en) * 2023-09-08 2023-09-27 Centrient Pharmaceuticals Netherlands B V Method for hydroxylation of bile acids or analogues thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1603864A (en) * 1978-05-25 1981-12-02 Nat Res Dev Microbiological oxidation processes
EP0007176A3 (de) * 1978-06-12 1980-02-20 Cetus Corporation Verfahren zur Herstellung von Epoxyden und Glykolen aus Alkenen
US4247641A (en) 1979-05-29 1981-01-27 Cetus Corporation Method for producing epoxides and glycols from alkenes
US4284723A (en) 1978-06-12 1981-08-18 Cetus Corporation Preparation of epoxides and glycols from gaseous alkenes
US4246347A (en) 1979-05-29 1981-01-20 Cetus Corporation Process for the production of fructose

Also Published As

Publication number Publication date
US6423702B1 (en) 2002-07-23
EP0540649A1 (de) 1993-05-12
FR2665179B1 (fr) 1995-03-03
JP3133327B2 (ja) 2001-02-05
JPH06500015A (ja) 1994-01-06
WO1992001803A1 (fr) 1992-02-06
DE69130611D1 (de) 1999-01-21
EP0540649B1 (de) 1998-12-09
FR2665179A1 (fr) 1992-01-31

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Legal Events

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8364 No opposition during term of opposition