DE69130221D1 - Oligosaccharidoxazolines, konjugate von oligosacchariden und verfahren zu ihrer herstellung - Google Patents

Oligosaccharidoxazolines, konjugate von oligosacchariden und verfahren zu ihrer herstellung

Info

Publication number
DE69130221D1
DE69130221D1 DE69130221T DE69130221T DE69130221D1 DE 69130221 D1 DE69130221 D1 DE 69130221D1 DE 69130221 T DE69130221 T DE 69130221T DE 69130221 T DE69130221 T DE 69130221T DE 69130221 D1 DE69130221 D1 DE 69130221D1
Authority
DE
Germany
Prior art keywords
oligosaccharidoxazolines
oligosaccharides
conjugates
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69130221T
Other languages
English (en)
Other versions
DE69130221T2 (de
Inventor
Marcelo Colon
Jeffrey Davis
James Rasmussen
Marianne Borowski
Barbara Wan
Shirish Hirani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genzyme Corp
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Application granted granted Critical
Publication of DE69130221D1 publication Critical patent/DE69130221D1/de
Publication of DE69130221T2 publication Critical patent/DE69130221T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/06Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69130221T 1990-05-25 1991-05-24 Oligosaccharidoxazolines, konjugate von oligosacchariden und verfahren zu ihrer herstellung Expired - Fee Related DE69130221T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/529,343 US5241072A (en) 1990-05-25 1990-05-25 Oligosaccharide oxazolines, oligosaccharide conjugates and methods of preparation thereof
PCT/US1991/003687 WO1991018911A2 (en) 1990-05-25 1991-05-24 Oligosaccharide oxazolines, oligosaccharide conjugates and methods of preparation thereof

Publications (2)

Publication Number Publication Date
DE69130221D1 true DE69130221D1 (de) 1998-10-22
DE69130221T2 DE69130221T2 (de) 1999-01-21

Family

ID=24109524

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69132586T Expired - Fee Related DE69132586T2 (de) 1990-05-25 1991-05-24 Konjugate von Oligosacchariden und Verfahren zu ihrer Herstellung
DE0860442T Pending DE860442T1 (de) 1990-05-25 1991-05-24 Oligosaccharidoxazolines, Konjugate von Oligosacchariden und Verfahren zu ihrer Herstellung
DE69130221T Expired - Fee Related DE69130221T2 (de) 1990-05-25 1991-05-24 Oligosaccharidoxazolines, konjugate von oligosacchariden und verfahren zu ihrer herstellung

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69132586T Expired - Fee Related DE69132586T2 (de) 1990-05-25 1991-05-24 Konjugate von Oligosacchariden und Verfahren zu ihrer Herstellung
DE0860442T Pending DE860442T1 (de) 1990-05-25 1991-05-24 Oligosaccharidoxazolines, Konjugate von Oligosacchariden und Verfahren zu ihrer Herstellung

Country Status (6)

Country Link
US (2) US5241072A (de)
EP (2) EP0535052B1 (de)
JP (1) JP3217059B2 (de)
CA (1) CA2081665C (de)
DE (3) DE69132586T2 (de)
WO (1) WO1991018911A2 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5718893A (en) * 1984-04-15 1998-02-17 Foster; Preston F. Use of G-CSF to reduce acute rejection
JP2794678B2 (ja) 1991-08-26 1998-09-10 株式会社 半導体エネルギー研究所 絶縁ゲイト型半導体装置およびその作製方法
US5485019A (en) 1992-02-05 1996-01-16 Semiconductor Energy Laboratory Co., Ltd. Semiconductor device and method for forming the same
DE4204315A1 (de) * 1992-02-13 1993-08-19 Consortium Elektrochem Ind Cyclodextringlycoside und verfahren zu ihrer herstellung
US6624450B1 (en) 1992-03-27 2003-09-23 Semiconductor Energy Laboratory Co., Ltd. Semiconductor device and method for forming the same
FR2693907B1 (fr) * 1992-07-23 1994-09-02 Rhone Poulenc Rorer Sa Procédé d'administration de solutions de facteur de stimulation des colonies granulocytaires.
EP0601417A3 (de) * 1992-12-11 1998-07-01 Hoechst Aktiengesellschaft Physiologisch verträglicher und physiologisch abbaubarer, Kohlenhydratrezeptorblocker auf Polymerbasis, ein Verfahren zu seiner Herstellung und seine Verwendung
US5536495A (en) * 1994-04-15 1996-07-16 Foster; Preston F. Use of G-CSF to reduce acute rejection
CN1309423C (zh) * 1999-11-12 2007-04-11 马克西根控股公司 干扰素γ偶联物
SK8292002A3 (en) * 1999-11-12 2002-12-03 Maxygen Holdings Ltd A conjugate exhibiting interferon gamma activity, nucleotide sequence encoding for a polypeptide fraction of conjugate, an expression vector and a host cell containing nucleotide sequence, pharmaceutical composition comprising the same and use thereof
AU782635B2 (en) * 1999-11-12 2005-08-18 Maxygen Holdings Ltd. Interferon gamma conjugates
KR100840092B1 (ko) * 2000-09-29 2008-06-19 후지 세이유 가부시키가이샤 혈중 중성 지방 저감용 조성물
KR20040008120A (ko) * 2001-02-20 2004-01-28 다카라 바이오 가부시키가이샤 수식제
US7038015B2 (en) 2001-04-06 2006-05-02 Maxygen Holdings, Ltd. Interferon gamma polypeptide variants
US6958388B2 (en) 2001-04-06 2005-10-25 Maxygen, Aps Interferon gamma polypeptide variants
EP1428015A4 (de) 2001-08-16 2008-09-17 Analiza Inc Verfahren zur löslichkeitsmessung
ES2342713T3 (es) * 2001-11-12 2010-07-13 Analiza, Inc. Caracterizacion de moleculas.
US7299805B2 (en) 2002-06-07 2007-11-27 Marctec, Llc Scaffold and method for implanting cells
EP1539814A2 (de) 2002-07-03 2005-06-15 Maxygen Holdings Ltd. c/o Close Brothers (Cayman) Limited Ungekürzte interferon-gamma-polypeptidvarianten
US8099242B2 (en) 2003-06-12 2012-01-17 Analiza, Inc. Systems and methods for characterization of molecules
US7220407B2 (en) 2003-10-27 2007-05-22 Amgen Inc. G-CSF therapy as an adjunct to reperfusion therapy in the treatment of acute myocardial infarction
EP1817047B1 (de) 2004-11-05 2012-02-08 Northwestern University Verwendung von scf und g-scf bei der behandlung von hirnischämie und neurologischen störungen
ATE545031T1 (de) * 2005-12-19 2012-02-15 Analiza Inc Verfahren unter beteiligung von datenmustern, wie etwa spektralen biomarkern
WO2014025961A1 (en) 2012-08-10 2014-02-13 Analiza, Inc. Methods and devices for analyzing species to determine diseases
US9678076B2 (en) 2014-06-24 2017-06-13 Analiza, Inc. Methods and devices for determining a disease state
CA2956188A1 (en) * 2014-08-08 2016-02-11 Glycovaxyn Ag Modified host cells for use in bioconjugate production
JP2022129250A (ja) * 2021-02-24 2022-09-05 学校法人 中央大学 ポリオキサゾリン結合アルブミン、人工血漿増量剤及び出血ショックの蘇生液
EP4423506A1 (de) 2021-10-28 2024-09-04 Cleveland Diagnostics, Inc. Partitionierungssysteme und verfahren zur bestimmung mehrerer krebsarten

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8203925D0 (sv) * 1982-06-23 1982-06-23 Svenska Sockerfabriks Ab New and novel glycosides, glycoconjugates and processes for their preparation
NZ214503A (en) * 1984-12-20 1990-02-26 Merck & Co Inc Covalently-modified neutral bacterial polysaccharides, stable covalent conjugates of such polysaccharides and immunogenic proteins, and methods of preparing such polysaccharides and conjugates
DK17685D0 (da) * 1985-01-14 1985-01-14 Hans Goeran Magnusson Glycosidderivater
DE3505150A1 (de) * 1985-02-15 1986-08-21 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von zuckerketalen
US4785084A (en) * 1986-07-31 1988-11-15 The General Hospital Corporation Method of preparing peracetyl oxazolines
JPH01502266A (ja) * 1986-12-11 1989-08-10 ジェンジム・コーポレーション 1―アミノ―1―デオキシオリゴ糖とその誘導体の製造

Also Published As

Publication number Publication date
EP0535052A1 (de) 1993-04-07
EP0535052B1 (de) 1998-09-16
WO1991018911A2 (en) 1991-12-12
US5659015A (en) 1997-08-19
CA2081665A1 (en) 1991-11-26
US5241072A (en) 1993-08-31
DE860442T1 (de) 1999-04-22
CA2081665C (en) 2002-01-01
DE69132586D1 (de) 2001-05-23
DE69130221T2 (de) 1999-01-21
WO1991018911A3 (en) 1992-05-14
JPH05507487A (ja) 1993-10-28
EP0860442B1 (de) 2001-04-18
JP3217059B2 (ja) 2001-10-09
EP0860442A1 (de) 1998-08-26
DE69132586T2 (de) 2002-04-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee