DE69128636T2 - Multidimensionales on-line chromatographiesystem mit grosser injektionskapazität für die überkritische fluidchromatographie - Google Patents
Multidimensionales on-line chromatographiesystem mit grosser injektionskapazität für die überkritische fluidchromatographieInfo
- Publication number
- DE69128636T2 DE69128636T2 DE69128636T DE69128636T DE69128636T2 DE 69128636 T2 DE69128636 T2 DE 69128636T2 DE 69128636 T DE69128636 T DE 69128636T DE 69128636 T DE69128636 T DE 69128636T DE 69128636 T2 DE69128636 T2 DE 69128636T2
- Authority
- DE
- Germany
- Prior art keywords
- supercritical fluid
- chromatograph
- fraction
- inlet column
- multidimensional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
- G01N2030/062—Preparation extracting sample from raw material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
- G01N30/12—Preparation by evaporation
- G01N2030/126—Preparation by evaporation evaporating sample
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/462—Flow patterns using more than one column with serial coupling of separation columns with different eluents or with eluents in different states
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Sampling And Sample Adjustment (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/594,403 US5139681A (en) | 1990-10-09 | 1990-10-09 | On-line multidimensional chromatographic system with large volume injection handling for supercritical fluid chromatography |
PCT/US1991/007437 WO1992005852A1 (en) | 1990-10-09 | 1991-10-08 | On-line multidimensional chromatographic system with large volume injection handling for supercritical fluid chromatography |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69128636D1 DE69128636D1 (de) | 1998-02-12 |
DE69128636T2 true DE69128636T2 (de) | 1998-04-23 |
Family
ID=24378721
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69128636T Expired - Fee Related DE69128636T2 (de) | 1990-10-09 | 1991-10-08 | Multidimensionales on-line chromatographiesystem mit grosser injektionskapazität für die überkritische fluidchromatographie |
Country Status (7)
Country | Link |
---|---|
US (1) | US5139681A (de) |
EP (1) | EP0552314B1 (de) |
JP (1) | JPH06502495A (de) |
AT (1) | ATE161743T1 (de) |
CA (1) | CA2093637A1 (de) |
DE (1) | DE69128636T2 (de) |
WO (1) | WO1992005852A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5372716A (en) * | 1991-02-28 | 1994-12-13 | Suprex Corporation | Supercritical fluid extraction coupled to analytical chromatography system |
US5458783A (en) * | 1992-08-13 | 1995-10-17 | Suprex Corporation | Supercritical fluid extraction coupled to analytical chromatography system |
US5346622A (en) * | 1993-03-04 | 1994-09-13 | Hewlett-Packard Company | Hydrocarbon class separation and quantitation by split column effluent analysis |
ES2152153B1 (es) * | 1998-05-22 | 2001-08-16 | Consejo Superior Investigacion | Dispositivo de interfase para el acoplamiento directo de cromatografia de liquidos y cromatografia de gases. |
US6502448B1 (en) | 1999-09-07 | 2003-01-07 | Edward Rapkin | Chromatography detection system and method |
US6413428B1 (en) | 1999-09-16 | 2002-07-02 | Berger Instruments, Inc. | Apparatus and method for preparative supercritical fluid chromatography |
US6685828B2 (en) | 1999-09-16 | 2004-02-03 | Berger Instruments, Inc. | Automated sample collection in supercritical fluid chromatography |
US6632353B2 (en) | 2000-06-26 | 2003-10-14 | Berger Instruments, Inc. | Rapid sample collection in supercritical fluid chromatography |
DE10255231B4 (de) * | 2002-11-26 | 2006-02-02 | Uhde High Pressure Technologies Gmbh | Hochdruckvorrichtung zum Verschließen eines Druckbehälters im Reinraum |
US7735352B2 (en) * | 2006-05-16 | 2010-06-15 | Alliant Techsystems Inc. | Multi-dimensional portable gas chromatograph system |
US8215922B2 (en) | 2008-06-24 | 2012-07-10 | Aurora Sfc Systems, Inc. | Compressible fluid pumping system for dynamically compensating compressible fluids over large pressure ranges |
US9163618B2 (en) | 2008-06-24 | 2015-10-20 | Agilent Technologies, Inc. | Automated conversion between SFC and HPLC |
US8419936B2 (en) | 2010-03-23 | 2013-04-16 | Agilent Technologies, Inc. | Low noise back pressure regulator for supercritical fluid chromatography |
WO2013086281A1 (en) * | 2011-12-09 | 2013-06-13 | Waters Technologies Corporation | Select valve for liquid chromatography systems |
EP2823280B1 (de) * | 2012-03-08 | 2023-04-26 | Waters Technologies Corporation | Einführung von proben in superkritische flüssigkeitschromatographiesysteme |
JP6232067B2 (ja) * | 2012-08-31 | 2017-11-15 | 西安奥▲嵐▼科技▲開▼▲発▼有限▲責▼任公司 | タンパク質分離用多次元の液体クロマトグラフィーの分離システム及分離方法 |
RU2678921C2 (ru) | 2014-10-27 | 2019-02-04 | Ф. Хоффманн-Ля Рош Аг | Системы и способы двумерной хроматографии rplc-sfc |
US11307181B1 (en) | 2018-07-14 | 2022-04-19 | Sielc Technologies Corporation | HPLC system with mixed-mode columns for measuring charged analytes in complex mixtures |
CN110208401B (zh) * | 2019-05-24 | 2021-11-02 | 岛津企业管理(中国)有限公司 | 固相脱水萃取-超临界流体色谱-质谱在线分析系统及方法 |
CN113533540A (zh) * | 2020-04-13 | 2021-10-22 | 株式会社岛津制作所 | 使用超临界流体的分析系统以及分析方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2036525B2 (de) * | 1970-07-23 | 1974-06-20 | Boehringer Mannheim Gmbh | Verfahren und Vorrichtung zur chromatographischen Auftrennung von Mehrstoffgemischen |
US4500432A (en) * | 1981-07-13 | 1985-02-19 | Hewlett-Packard Company | Automated sample concentrator for trace components |
US4479380A (en) * | 1982-02-26 | 1984-10-30 | Brigham Young University | Open-tubular supercritical fluid chromatography |
FR2527934A1 (fr) * | 1982-06-03 | 1983-12-09 | Elf Aquitaine | Procede de fractionnement de melanges par chromatographie d'elution avec fluide en etat supercritique et installation pour sa mise en oeuvre |
US4597943A (en) * | 1984-11-29 | 1986-07-01 | Morinaga & Co., Ltd. | Apparatus for analyzing solid sample with supercritical fluid |
CA1256714A (en) * | 1985-01-25 | 1989-07-04 | Hernan J. Cortes | On-line coupled liquid and gas chromatography system with an interface capillary tube interposed between a pair of capillary chromatographic columns |
US4935145A (en) * | 1985-01-25 | 1990-06-19 | The Dow Chemical Company | On-line coupled liquid and gas chromatography system |
US4793920A (en) * | 1985-12-11 | 1988-12-27 | Lee Scientific, Inc. | Chromatography columns with cast porous plugs and methods of fabricating same |
JPS62138753A (ja) * | 1985-12-12 | 1987-06-22 | Hitachi Ltd | 液体クロマトグラフイによる分画・分取方法および装置 |
EP0275933B1 (de) * | 1987-01-17 | 1994-07-27 | Jasco Corporation | Druckregelapparat |
US4775476A (en) * | 1987-11-02 | 1988-10-04 | The Dow Chemical Company | Method for membrane assisted liquid chromatography |
US4913821A (en) * | 1989-04-27 | 1990-04-03 | The Dow Chemical Company | Method for the determination of phenols in water |
-
1990
- 1990-10-09 US US07/594,403 patent/US5139681A/en not_active Expired - Fee Related
-
1991
- 1991-10-08 CA CA002093637A patent/CA2093637A1/en not_active Abandoned
- 1991-10-08 JP JP4500682A patent/JPH06502495A/ja active Pending
- 1991-10-08 WO PCT/US1991/007437 patent/WO1992005852A1/en active IP Right Grant
- 1991-10-08 AT AT92902592T patent/ATE161743T1/de not_active IP Right Cessation
- 1991-10-08 DE DE69128636T patent/DE69128636T2/de not_active Expired - Fee Related
- 1991-10-08 EP EP92902592A patent/EP0552314B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5139681A (en) | 1992-08-18 |
CA2093637A1 (en) | 1992-04-10 |
DE69128636D1 (de) | 1998-02-12 |
EP0552314A1 (de) | 1993-07-28 |
ATE161743T1 (de) | 1998-01-15 |
JPH06502495A (ja) | 1994-03-17 |
WO1992005852A1 (en) | 1992-04-16 |
EP0552314A4 (de) | 1995-01-25 |
EP0552314B1 (de) | 1998-01-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |