DE69128108D1 - Monoklonaler Antikörper gegen HTLV-III (Stamm MN) - Google Patents
Monoklonaler Antikörper gegen HTLV-III (Stamm MN)Info
- Publication number
- DE69128108D1 DE69128108D1 DE69128108T DE69128108T DE69128108D1 DE 69128108 D1 DE69128108 D1 DE 69128108D1 DE 69128108 T DE69128108 T DE 69128108T DE 69128108 T DE69128108 T DE 69128108T DE 69128108 D1 DE69128108 D1 DE 69128108D1
- Authority
- DE
- Germany
- Prior art keywords
- htlv
- iiimn
- binding
- monoclonal antibody
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 3
- 102000003886 Glycoproteins Human genes 0.000 abstract 2
- 108090000288 Glycoproteins Proteins 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 239000002245 particle Substances 0.000 abstract 2
- 230000003612 virological effect Effects 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000017960 syncytium formation Effects 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17507590 | 1990-07-02 | ||
JP2188300A JP2989862B2 (ja) | 1990-07-02 | 1990-07-16 | モノクローナル抗体 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69128108D1 true DE69128108D1 (de) | 1997-12-11 |
DE69128108T2 DE69128108T2 (de) | 1998-03-26 |
Family
ID=26496454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69128108T Expired - Fee Related DE69128108T2 (de) | 1990-07-02 | 1991-07-01 | Monoklonaler Antikörper gegen HTLV-III (Stamm MN) |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0465979B1 (de) |
JP (1) | JP2989862B2 (de) |
AT (1) | ATE159983T1 (de) |
AU (1) | AU641026B2 (de) |
DE (1) | DE69128108T2 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2128222C1 (ru) * | 1991-08-22 | 1999-03-27 | Ниссин Сокухин Кабусики Кайся | Мышиное моноклональное антитело nm01, гибридомная клеточная линия, фрагмент мышиного могоклонального антитела (варианты) |
US5558865A (en) * | 1991-08-22 | 1996-09-24 | Nissin Shokuhin Kabushiki Kaisha | HIV immunotherapeutics |
DK0678523T3 (da) * | 1993-01-14 | 2005-01-10 | Chemo Sero Therapeut Res Inst | Rekombinant anti-HIV antistof og fremstilling deraf |
KR100266554B1 (ko) * | 1993-01-14 | 2000-09-15 | 사꼬 미쓰오 | 재조합항-hiv항체및그의제조방법 |
US7048935B2 (en) | 1995-04-27 | 2006-05-23 | The United States Of America As Represented By The Department Of Health And Human Services | Cyanovirin conjugates and matrix-anchored cyanovirin and related compositions and methods of use |
US6987096B1 (en) | 1995-04-27 | 2006-01-17 | The United States Of America As Represented By The Department Of Health And Human Services | Antiviral proteins and peptides, DNA coding sequences therefor, and uses thereof |
US6193982B1 (en) | 1995-04-27 | 2001-02-27 | The United States Of America As Represented By The Department Of Health & Human Services | Anti-cyanovirin antibody with an internal image of gp120, a method of use thereof, and a method of using a cyanovirin to induce an immune response to gp120 |
US6780847B2 (en) | 1995-04-27 | 2004-08-24 | The United States Of America As Represented By The Department Of Health And Human Services | Glycosylation-resistant cyanovirins and related conjugates, compositions, nucleic acids, vectors, host cells, methods of production and methods of using nonglycosylated cyanovirins |
US6428790B1 (en) | 1995-04-27 | 2002-08-06 | The United States Of America As Represented By The Secretary Department Of Health And Human Services | Cyanovirin conjugates and matrix-anchored cyanovirin and related compositions and methods of use |
US5843882A (en) | 1995-04-27 | 1998-12-01 | The United States Of America As Represented By The Department Of Health And Human Services | Antiviral proteins and peptides |
JP4307841B2 (ja) | 2001-03-22 | 2009-08-05 | アメリカ合衆国 | グリコシル化抵抗性シアノビリン及び関連コンジュゲート、組成物、核酸、ベクター、宿主細胞、非グリコシル化シアノビリンの製造方法及び使用方法 |
CN102066418A (zh) | 2007-11-19 | 2011-05-18 | 国立大学法人熊本大学 | 抗hiv单克隆抗体 |
CN114667281A (zh) | 2019-10-29 | 2022-06-24 | 国立大学法人熊本大学 | 具有抗hiv活性的cd4模拟物化合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3853779T2 (de) * | 1987-05-29 | 1995-09-07 | Baylor College Medicine | Hiv-1 neutralisierende monoklonale antikörper. |
EP0339504A3 (de) * | 1988-04-26 | 1990-09-12 | The Du Pont Merck Pharmaceutical Company | Menschliches immunoinsuffizientes Virus (HIV) env-codiertes Peptid, welches im Stande ist, die HIV hemmenden Antikörper bei Säugetieren hervorzurufen |
EP0436634A1 (de) * | 1988-10-03 | 1991-07-17 | Repligen Corporation | Hiv-proteine und peptide und deren verwendung zur diagnose, prophylaxe und therapie von aids |
WO1990015078A1 (en) * | 1989-06-05 | 1990-12-13 | Scott Charles F Jr | HUMAN MONOCLONAL ANTIBODIES TO HIV-1MN gp 120 |
-
1990
- 1990-07-16 JP JP2188300A patent/JP2989862B2/ja not_active Expired - Fee Related
-
1991
- 1991-07-01 AT AT91110884T patent/ATE159983T1/de not_active IP Right Cessation
- 1991-07-01 EP EP91110884A patent/EP0465979B1/de not_active Expired - Lifetime
- 1991-07-01 AU AU80107/91A patent/AU641026B2/en not_active Ceased
- 1991-07-01 DE DE69128108T patent/DE69128108T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU641026B2 (en) | 1993-09-09 |
DE69128108T2 (de) | 1998-03-26 |
JP2989862B2 (ja) | 1999-12-13 |
ATE159983T1 (de) | 1997-11-15 |
JPH04152893A (ja) | 1992-05-26 |
EP0465979A1 (de) | 1992-01-15 |
EP0465979B1 (de) | 1997-11-05 |
AU8010791A (en) | 1992-01-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Ljunggren et al. | Antibody-dependent cellular cytotoxicity-inducing antibodies against human immunodeficiency virus. Presence at different clinical stages. | |
Nara et al. | Persistent infection of chimpanzees with human immunodeficiency virus: serological responses and properties of reisolated viruses | |
Nara et al. | Purified envelope glycoproteins from human immunodeficiency virus type 1 variants induce individual, type-specific neutralizing antibodies | |
DE69128108D1 (de) | Monoklonaler Antikörper gegen HTLV-III (Stamm MN) | |
AU632475B2 (en) | Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals | |
DE3853779D1 (de) | Hiv-1 neutralisierende monoklonale antikörper. | |
Cavacini et al. | Binding and neutralization activity of human IgG1 and IgG3 from serum of HIV-infected individuals | |
CA2091263A1 (en) | Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus | |
DE69332911D1 (de) | Rekombinanter humanisierter Antikörper gegen menschlichen Immunschwächevirus | |
EP0470184A4 (en) | Antibodies specific for cd4-binding domain of hiv | |
DE3855134D1 (de) | Monoklonale menschliche antikörper gegen hiv-i | |
EP1016671A3 (de) | Menschliche, monoklonale Antikörper gegen das transmembrane Glycoprotein (gp41) des HIV-1, und verwandte Peptide | |
CA2192512A1 (en) | Nm03 antibody materials and methods | |
KR930702509A (ko) | 사람 면역결핍 바이러스(hiv)면역치료제 | |
Broliden et al. | Identification of amino acids in the V3 region of gp120 critical for virus neutralization by human HIV-1-specific antibodies. | |
AU659839B2 (en) | Human immunodeficiency virus-related immune preparation | |
CA2046016A1 (en) | Hiv monoclonal antibody | |
CA2160696A1 (en) | Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus | |
ATE128733T1 (de) | Monoklonale antikörper gegen hiv gp120. | |
Mathiesen et al. | Fine analysis of intrathecally synthesized anti-HIV IgG1-4 by peptide mapping | |
LONDOS-GAGLIARDI et al. | Antibodies directed against a variable and neutralizable region of the HTLV-I envelope surface glycoprotein. | |
ATE137801T1 (de) | Gegen hiv 1 gp48 spezifische antikörper | |
ATE136789T1 (de) | Antigene eines transmembranen hüllenglycoproteins eines menschlichen retrovirus des typs hiv-2 und immunologisch verwandte antigene | |
AU627540B2 (en) | Drug for the treatment or prevention by passive immunization, of the hiv-infection and process for preparation thereof | |
Broliden | The specificity and function of HIV antibody response. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |