DE69123248D1 - Verfahren zur herstellung einer wässrigen suspension - Google Patents

Verfahren zur herstellung einer wässrigen suspension

Info

Publication number
DE69123248D1
DE69123248D1 DE69123248T DE69123248T DE69123248D1 DE 69123248 D1 DE69123248 D1 DE 69123248D1 DE 69123248 T DE69123248 T DE 69123248T DE 69123248 T DE69123248 T DE 69123248T DE 69123248 D1 DE69123248 D1 DE 69123248D1
Authority
DE
Germany
Prior art keywords
aqueous suspension
producing
pentyloxyphenyl
thiazolidine
ethoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69123248T
Other languages
English (en)
Other versions
DE69123248T2 (de
Inventor
Hisayuki Nakayama
Kazumichi Ushio
Katsuhiro Inada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd filed Critical Senju Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE69123248D1 publication Critical patent/DE69123248D1/de
Publication of DE69123248T2 publication Critical patent/DE69123248T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Lasers (AREA)
  • Lighting Device Outwards From Vehicle And Optical Signal (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DE69123248T 1991-03-27 1991-07-11 Verfahren zur herstellung einer wässrigen suspension Expired - Fee Related DE69123248T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP6290991 1991-03-27
PCT/JP1991/000932 WO1992017174A1 (en) 1991-03-27 1991-07-11 Process for preparing aqueous suspension

Publications (2)

Publication Number Publication Date
DE69123248D1 true DE69123248D1 (de) 1997-01-02
DE69123248T2 DE69123248T2 (de) 1997-03-13

Family

ID=13213855

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69123248T Expired - Fee Related DE69123248T2 (de) 1991-03-27 1991-07-11 Verfahren zur herstellung einer wässrigen suspension

Country Status (14)

Country Link
US (1) US5366985A (de)
EP (1) EP0531529B1 (de)
KR (1) KR0181973B1 (de)
AT (1) ATE145328T1 (de)
AU (2) AU650889B2 (de)
CA (1) CA2083842A1 (de)
DE (1) DE69123248T2 (de)
DK (1) DK0531529T3 (de)
ES (1) ES2094227T3 (de)
FI (1) FI100694B (de)
NO (1) NO301215B1 (de)
RU (1) RU2098094C1 (de)
TW (1) TW207500B (de)
WO (1) WO1992017174A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1284030B1 (it) * 1996-06-18 1998-05-08 Solchem Italiana Spa Metodo per la produzione di sospensioni acquose stabili, utili nelle composizioni farmaceutiche
DE69837664T2 (de) 1997-05-14 2008-01-03 Senju Pharmaceutical Co., Ltd. Wässrige suspensionspräparationen mit exzellenter redispersibilität
US6858230B1 (en) * 1999-04-12 2005-02-22 Shionogi & Co., Ltd. Process for producing medicinal composition of basic hydrophobic medicinal compound
CA2839847C (en) * 2003-06-13 2016-03-15 Masood A. Chowhan Ophthalmic compositions containing a synergistic combination of two polymers
US7947295B2 (en) 2003-06-13 2011-05-24 Alcon, Inc. Ophthalmic compositions containing a synergistic combination of two polymers
TWI363626B (en) 2004-11-15 2012-05-11 Otsuka Pharma Co Ltd Aqueous ophthalmic suspension of crystalline rebamipide
WO2007058935A2 (en) * 2005-11-14 2007-05-24 Bausch & Lomb Incorporated Ophthalmic composition for dry eye therapy
TW200808375A (en) * 2006-05-12 2008-02-16 Otsuka Pharma Co Ltd Hydrogel suspension and manufacturing process thereof
TWI415629B (zh) * 2006-10-26 2013-11-21 Otsuka Pharma Co Ltd 含有瑞巴匹特之水性醫藥懸浮物及其製造方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6610081A (en) * 1980-01-24 1981-07-30 Senju Pharmaceutical Co., Ltd. Thiazolidine derivatives
JPS6143114A (ja) * 1984-08-03 1986-03-01 Takeda Chem Ind Ltd 虹彩・毛様体疾患治療用眼局所投与剤
US5192535A (en) * 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions

Also Published As

Publication number Publication date
FI925353A (fi) 1992-11-25
US5366985A (en) 1994-11-22
CA2083842A1 (en) 1992-09-28
DK0531529T3 (da) 1997-04-21
FI100694B (fi) 1998-02-13
NO924549L (no) 1992-11-25
NO924549D0 (no) 1992-11-25
FI925353A0 (fi) 1992-11-25
DE69123248T2 (de) 1997-03-13
KR0181973B1 (ko) 1999-05-01
AU650889B2 (en) 1994-07-07
EP0531529A4 (en) 1993-08-04
NO301215B1 (no) 1997-09-29
ATE145328T1 (de) 1996-12-15
EP0531529A1 (de) 1993-03-17
KR930700097A (ko) 1993-03-13
WO1992017174A1 (en) 1992-10-15
AU6188894A (en) 1994-06-30
RU2098094C1 (ru) 1997-12-10
AU661944B2 (en) 1995-08-10
AU8104791A (en) 1992-11-02
EP0531529B1 (de) 1996-11-20
ES2094227T3 (es) 1997-01-16
TW207500B (de) 1993-06-11

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee