DE69119568D1 - Verfahren und Vorrichtung zur zweidimensionalen Messung der Konzentration von biologischen Makromolekülen einer Lösung - Google Patents

Verfahren und Vorrichtung zur zweidimensionalen Messung der Konzentration von biologischen Makromolekülen einer Lösung

Info

Publication number
DE69119568D1
DE69119568D1 DE69119568T DE69119568T DE69119568D1 DE 69119568 D1 DE69119568 D1 DE 69119568D1 DE 69119568 T DE69119568 T DE 69119568T DE 69119568 T DE69119568 T DE 69119568T DE 69119568 D1 DE69119568 D1 DE 69119568D1
Authority
DE
Germany
Prior art keywords
concentration
solution
dimensional measurement
biological macromolecules
macromolecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69119568T
Other languages
English (en)
Other versions
DE69119568T2 (de
Inventor
Kotaro Oka
Koji Asano
Shozo Fujita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujitsu Ltd
Original Assignee
Fujitsu Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujitsu Ltd filed Critical Fujitsu Ltd
Application granted granted Critical
Publication of DE69119568D1 publication Critical patent/DE69119568D1/de
Publication of DE69119568T2 publication Critical patent/DE69119568T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • C—CHEMISTRY; METALLURGY
    • C30—CRYSTAL GROWTH
    • C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
    • C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/5907—Densitometers
    • G01N21/5911—Densitometers of the scanning type
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N25/00—Investigating or analyzing materials by the use of thermal means
    • G01N25/14—Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation
    • G01N25/147—Investigating or analyzing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation by cristallisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G01N21/5907—Densitometers
    • G01N2021/5957—Densitometers using an image detector type detector, e.g. CCD
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/33—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light

Landscapes

  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
DE69119568T 1990-12-18 1991-12-18 Verfahren und Vorrichtung zur zweidimensionalen Messung der Konzentration von biologischen Makromolekülen einer Lösung Expired - Fee Related DE69119568T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2403315A JP2914758B2 (ja) 1990-12-18 1990-12-18 タンパク質溶液濃度の２次元測定方法および装置

Publications (2)

Publication Number Publication Date
DE69119568D1 true DE69119568D1 (de) 1996-06-20
DE69119568T2 DE69119568T2 (de) 1996-09-19

Family

ID=18513063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69119568T Expired - Fee Related DE69119568T2 (de) 1990-12-18 1991-12-18 Verfahren und Vorrichtung zur zweidimensionalen Messung der Konzentration von biologischen Makromolekülen einer Lösung

Country Status (5)

Country Link
US (1) US5214288A (de)
EP (1) EP0491558B1 (de)
JP (1) JP2914758B2 (de)
CA (1) CA2057558C (de)
DE (1) DE69119568T2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3094880B2 (ja) * 1995-03-01 2000-10-03 住友金属工業株式会社 有機化合物の結晶化制御方法およびそれに用いる結晶化制御用固体素子
GB9509410D0 (en) * 1995-05-10 1995-07-05 Imperial College Molecular imaging
JP4020539B2 (ja) * 1999-06-29 2007-12-12 ジーイーヘルスケア バイオサイエンス株式会社 水晶発振子を用いた液滴中の溶質濃度測定方法
DE10036880A1 (de) * 2000-07-28 2002-02-07 Basf Ag Regelung einer Waschkolonne in einem Schmelzkristallisationsprozess
WO2002097404A1 (en) * 2001-05-30 2002-12-05 Sciperio, Inc. System, method, and apparatus for non-intrusively determining concentration of a solute in a solution
AU2003256469A1 (en) * 2002-07-10 2004-01-23 Uab Research Foundation Method for distinguishing between biomolecule and non-biomolecule crystals
JP4113063B2 (ja) * 2003-08-18 2008-07-02 株式会社リガク 特定高分子結晶の検出方法
JP4458513B2 (ja) 2003-08-18 2010-04-28 株式会社リガク 特定高分子結晶の評価装置
DE102004005878A1 (de) * 2004-02-05 2005-09-01 Rina-Netzwerk Rna Technologien Gmbh Verfahren zur Überwachung der Herstellung von Biomolekülkristallen
US7545495B2 (en) * 2004-04-27 2009-06-09 Abbott Laboratories Methods for visualizing crystals and distinguishing crystals from other matter within a biological sample
US20050237522A1 (en) * 2004-04-27 2005-10-27 Swift Kerry M Methods for visualizing crystals and distinguishing crystals from other matter within a biological sample
US20070088508A1 (en) * 2005-09-28 2007-04-19 Scott Childs Cocrystallization methods
ES2368798T3 (es) 2006-09-12 2011-11-22 Sulzer Chemtech Ag Procedimiento para la purificación de líquidos iónicos.
US20080225265A1 (en) * 2007-03-17 2008-09-18 Mi Research, Inc. Method and apparatus for finding macromolecule crystallization conditions

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3751167A (en) * 1971-02-23 1973-08-07 G Claus Method and apparatus for continuous monitoring of dissolved organics
DE2741068A1 (de) * 1977-09-13 1979-03-22 Arnold Dipl Phys Dr Binder Verfahren und vorrichtung zur diagnose an gewebeproben
US4192996A (en) * 1978-07-12 1980-03-11 Hewlett-Packard Company Measurement of oxygen by differential absorption of UV radiation
US4587428A (en) * 1980-09-29 1986-05-06 Arnold Binder Method and apparatus for the diagnosis of tissue samples
JPS5892841A (ja) * 1981-11-28 1983-06-02 Shimadzu Corp 濃度計
JPS62106000A (ja) * 1985-10-30 1987-05-16 Fujitsu Ltd 生体高分子結晶自動作製装置
US4845552A (en) * 1987-08-20 1989-07-04 Bruno Jaggi Quantitative light microscope using a solid state detector in the primary image plane
US4919899A (en) * 1988-02-29 1990-04-24 Herrmann Frederick T Crystal growth apparatus

Also Published As

Publication number Publication date
DE69119568T2 (de) 1996-09-19
CA2057558A1 (en) 1992-06-19
EP0491558B1 (de) 1996-05-15
JP2914758B2 (ja) 1999-07-05
EP0491558A3 (en) 1992-11-19
CA2057558C (en) 1995-01-03
US5214288A (en) 1993-05-25
EP0491558A2 (de) 1992-06-24
JPH04216441A (ja) 1992-08-06

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee