DE69109286D1 - Pharmazeutische zusammensetzung. - Google Patents

Pharmazeutische zusammensetzung.

Info

Publication number
DE69109286D1
DE69109286D1 DE69109286T DE69109286T DE69109286D1 DE 69109286 D1 DE69109286 D1 DE 69109286D1 DE 69109286 T DE69109286 T DE 69109286T DE 69109286 T DE69109286 T DE 69109286T DE 69109286 D1 DE69109286 D1 DE 69109286D1
Authority
DE
Germany
Prior art keywords
pharmaceutical composition
core
prostaglandin
coating
nsaid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69109286T
Other languages
English (en)
Other versions
DE69109286T2 (de
Inventor
Rene Gimet
Jean-Charles Jinot
Christian Magnet
Isabelle Maroteaux
Francoise Nevoux
Roger Scoyer
Barbara Struthers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GD Searle LLC
Original Assignee
GD Searle LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24063571&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69109286(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by GD Searle LLC filed Critical GD Searle LLC
Application granted granted Critical
Publication of DE69109286D1 publication Critical patent/DE69109286D1/de
Publication of DE69109286T2 publication Critical patent/DE69109286T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DE69109286T 1990-05-03 1991-05-01 Pharmazeutische zusammensetzung. Expired - Lifetime DE69109286T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51835390A 1990-05-03 1990-05-03
PCT/US1991/002980 WO1991016895A1 (en) 1990-05-03 1991-05-01 Pharmaceutical composition

Publications (2)

Publication Number Publication Date
DE69109286D1 true DE69109286D1 (de) 1995-06-01
DE69109286T2 DE69109286T2 (de) 1995-09-28

Family

ID=24063571

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69109286T Expired - Lifetime DE69109286T2 (de) 1990-05-03 1991-05-01 Pharmazeutische zusammensetzung.

Country Status (15)

Country Link
US (2) US5601843A (de)
EP (1) EP0527887B1 (de)
AT (1) ATE121625T1 (de)
AU (1) AU7876491A (de)
CA (1) CA2082944C (de)
DE (1) DE69109286T2 (de)
DK (1) DK0527887T3 (de)
ES (1) ES2071312T3 (de)
GR (1) GR3015939T3 (de)
IE (1) IE68596B1 (de)
IL (1) IL98033A (de)
NZ (1) NZ238024A (de)
PT (1) PT97562B (de)
WO (1) WO1991016895A1 (de)
ZA (1) ZA913353B (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69109286T2 (de) * 1990-05-03 1995-09-28 Searle & Co Pharmazeutische zusammensetzung.
FI93924C (fi) * 1991-09-17 1995-06-26 Martti Lauri Antero Marvola Menetelmä säädellysti lääkeainetta vapauttavan valmisteen valmistamiseksi
US5324746A (en) * 1993-02-12 1994-06-28 Mckee Rex N Method of treating damaged mucosal and epithelial tissues with misoprostol
DE4341442C2 (de) * 1993-12-04 1998-11-05 Lohmann Therapie Syst Lts Vorrichtung zur kontrollierten Freisetzung von Wirkstoffen sowie ihre Verwendung
EP0853481A1 (de) * 1995-09-27 1998-07-22 Merck Frosst Canada Inc. Zusammensetzungen zur behandlung von entzündungen, die gewisse prostaglandine und ein cyclooxygenase-2 hemmer enthalten
US6623759B2 (en) * 1996-06-28 2003-09-23 Astrazeneca Ab Stable drug form for oral administration with benzimidazole derivatives as active ingredient and process for the preparation thereof
KR20010021625A (ko) 1997-07-09 2001-03-15 추후보정 개선된 남성발기 기능장애 치료방법 및 그 조성물
US6103765A (en) 1997-07-09 2000-08-15 Androsolutions, Inc. Methods for treating male erectile dysfunction
CA2241342C (en) * 1998-06-15 2000-02-08 Bernard Charles Sherman Pharmaceutical tablets comprising an nsaid and a prostaglandin
GB9814215D0 (en) * 1998-07-01 1998-09-02 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
US6319519B2 (en) 1998-07-07 2001-11-20 Norton Healthcare Ltd. Anti-inflammatory pharmaceutical formulations
US6514525B2 (en) 1998-09-10 2003-02-04 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
US6387410B1 (en) 1998-09-10 2002-05-14 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
GB9819685D0 (en) * 1998-09-10 1998-11-04 Norton Healthcare Ltd Anti-inflammatory pharmaceutical formulations
SE9803761D0 (sv) * 1998-11-04 1998-11-04 Synphora Ab Method to avoid increased iridial pigmentation during prostaglandin treatment
US7429407B2 (en) * 1998-12-30 2008-09-30 Aeromatic Fielder Ag Process for coating small bodies, including tablets
CA2259727A1 (en) * 1999-01-18 2000-07-18 Bernard Charles Sherman A two-layer pharmaceutical tablet comprising an nsaid and misoprostol
US6183779B1 (en) * 1999-03-22 2001-02-06 Pharmascience Inc. Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin
CA2277407A1 (en) * 1999-07-14 2001-01-14 Bernard Charles Sherman Pharmaceutical tablet comprising an nsaid and misoprostol
CA2387288A1 (en) * 1999-10-01 2001-04-12 Norton Healthcare Ltd. Anti-inflammatory pharmaceutical formulations
US6761895B2 (en) * 2000-04-17 2004-07-13 Yamanouchi Pharmaceutical Co., Ltd. Drug delivery system for averting pharmacokinetic drug interaction and method thereof
WO2003079972A2 (en) 2002-02-22 2003-10-02 New River Parmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
WO2004064815A1 (en) * 2003-01-21 2004-08-05 Smartrix Technologies Inc. Oral dosage formulation
DE602004007315D1 (de) * 2003-03-03 2007-08-16 Personnes A Responsibilite Lim Stabilisierte pharmazeutische Zusammensetzung enthaltend einen NSAID und einen Prostaglandin
WO2004091579A1 (en) * 2003-04-16 2004-10-28 Pharmacia Corporation Stabilized prostaglandin formulation
US7241746B2 (en) 2003-08-06 2007-07-10 Regena Therapeutics, Lc Method and composition for treating periodontal disease
US20050163847A1 (en) * 2004-01-21 2005-07-28 Andrx Pharmaceuticals, Llc Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and an antiulcerative drug
US20060024368A1 (en) * 2004-07-30 2006-02-02 Reza Fassihi Compressed composite delivery system for release-rate modulation of bioactives
US20060073202A1 (en) * 2004-10-05 2006-04-06 Rocca Jose G Dual component medicament delivery system
US20080020040A1 (en) * 2006-07-18 2008-01-24 Horizon Therapeutics, Inc. Unit dose form for administration of ibuprofen
US20080021078A1 (en) * 2006-07-18 2008-01-24 Horizon Therapeutics, Inc. Methods and medicaments for administration of ibuprofen
US8067451B2 (en) 2006-07-18 2011-11-29 Horizon Pharma Usa, Inc. Methods and medicaments for administration of ibuprofen
US8067033B2 (en) 2007-11-30 2011-11-29 Horizon Pharma Usa, Inc. Stable compositions of famotidine and ibuprofen
US20150224056A1 (en) * 2006-07-18 2015-08-13 Horizon Pharma Usa, Inc. Pharmaceutical compositions of ibuprofen and famotidine
EP2063873A2 (de) * 2006-08-31 2009-06-03 Horizon Therapeutics, Inc. Nsaid-dosierungseinheitsformulierungen mit h2-rezeptor-antagonisten und verfahren zu ihrer verwendung
US8574625B2 (en) 2007-05-30 2013-11-05 Wockhardt Ltd. Tablet dosage form
KR20110079641A (ko) 2008-09-09 2011-07-07 아스트라제네카 아베 제약 조성물을 이를 필요로 하는 환자에게 전달하는 방법
EP2210595A1 (de) 2009-01-14 2010-07-28 LEK Pharmaceuticals d.d. Aktive Beschichtung von pharmazeutischen Dosierungsformen
EA021112B1 (ru) * 2009-06-25 2015-04-30 Поузен Инк. Способ лечения боли и/или воспаления у пациента, нуждающегося в аспириновой терапии
SG176724A1 (en) 2009-06-25 2012-01-30 Astrazeneca Ab Method for treating a patient at risk for developing an nsaid-associated ulcer
US9539214B2 (en) 2011-12-28 2017-01-10 Pozen Inc. Compositions and methods for delivery of omeprazole plus acetylsalicylic acid
US20190117669A1 (en) * 2016-04-11 2019-04-25 University Of Utah Research Foundation Methods for Treating NSAID-Induced Cardiovascular, Cerebrovascular, or Renovascular Adverse Events

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2135881A (en) * 1983-03-02 1984-09-12 Erba Farmitalia Method and pharmaceutical compositions for inhibiting or reducing gastrointestinal side effects of non-steroidal anti-inflammatory drugs
IT1190400B (it) * 1985-10-04 1988-02-16 Istituto Biochimico Italiano Derivati dell'acido 19,20-bis,nor-prostanoico ad attivita' antiulcera e anoressivca,procedimento per la loro preparazione e composizioni farmaceutiche
US4707495A (en) * 1985-10-28 1987-11-17 Ortho Pharmaceutical Peptic ulcer treatment method
US4975283A (en) * 1985-12-12 1990-12-04 Bristol-Myers Squibb Company Stabilized enteric coated aspirin granules and process for preparation
DE3603576A1 (de) * 1986-02-06 1987-08-13 Code Kaffee Handel Verwendung von gerbstoffen und/oder chlorogensaeure sowie nahrungs-, genuss- und/oder arzneimittel mit gerbstoff- und/oder chlorogensaeurezusatz
JPH01139528A (ja) * 1987-11-24 1989-06-01 Showa Denko Kk 抗潰瘍剤
DE69109286T2 (de) * 1990-05-03 1995-09-28 Searle & Co Pharmazeutische zusammensetzung.

Also Published As

Publication number Publication date
ES2071312T3 (es) 1995-06-16
US5698225A (en) 1997-12-16
IE911486A1 (en) 1991-11-06
ZA913353B (en) 1993-04-28
PT97562B (pt) 1998-08-31
IE68596B1 (en) 1996-06-26
DE69109286T2 (de) 1995-09-28
AU7876491A (en) 1991-11-27
NZ238024A (en) 1993-08-26
ATE121625T1 (de) 1995-05-15
CA2082944A1 (en) 1991-11-04
IL98033A0 (en) 1992-06-21
WO1991016895A1 (en) 1991-11-14
US5601843A (en) 1997-02-11
IL98033A (en) 1995-07-31
DK0527887T3 (da) 1995-07-03
EP0527887A1 (de) 1993-02-24
EP0527887B1 (de) 1995-04-26
CA2082944C (en) 1998-11-24
GR3015939T3 (en) 1995-07-31
PT97562A (pt) 1992-02-28

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